| Full name: docking protein 7 | Alias Symbol: FLJ33718|FLJ39137|Dok-7 | ||
| Type: protein-coding gene | Cytoband: 4p16.3 | ||
| Entrez ID: 285489 | HGNC ID: HGNC:26594 | Ensembl Gene: ENSG00000175920 | OMIM ID: 610285 |
| Drug and gene relationship at DGIdb | |||
Expression of DOK7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DOK7 | 285489 | 240633_at | -0.1635 | 0.4943 | |
| GSE26886 | DOK7 | 285489 | 240633_at | 0.7275 | 0.0423 | |
| GSE45670 | DOK7 | 285489 | 240633_at | -0.0060 | 0.9806 | |
| GSE53622 | DOK7 | 285489 | 33101 | -0.1422 | 0.5956 | |
| GSE53624 | DOK7 | 285489 | 33101 | -0.6204 | 0.0011 | |
| GSE63941 | DOK7 | 285489 | 240633_at | 1.1051 | 0.1354 | |
| GSE77861 | DOK7 | 285489 | 240633_at | -0.0095 | 0.9477 | |
| GSE97050 | DOK7 | 285489 | A_33_P3318368 | -0.1645 | 0.4558 | |
| SRP133303 | DOK7 | 285489 | RNAseq | -0.8512 | 0.0064 | |
| SRP219564 | DOK7 | 285489 | RNAseq | 0.8648 | 0.1270 | |
| TCGA | DOK7 | 285489 | RNAseq | -1.2468 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DOK7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DOK7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DOK7 | 285489 | 0 | 17 | 13 | |
| GSE20123 | DOK7 | 285489 | 0 | 17 | 13 | |
| GSE43470 | DOK7 | 285489 | 0 | 18 | 25 | |
| GSE46452 | DOK7 | 285489 | 1 | 36 | 22 | |
| GSE47630 | DOK7 | 285489 | 1 | 19 | 20 | |
| GSE54993 | DOK7 | 285489 | 10 | 0 | 60 | |
| GSE54994 | DOK7 | 285489 | 3 | 12 | 38 | |
| GSE60625 | DOK7 | 285489 | 0 | 0 | 11 | |
| GSE74703 | DOK7 | 285489 | 0 | 14 | 22 | |
| GSE74704 | DOK7 | 285489 | 0 | 9 | 11 | |
| TCGA | DOK7 | 285489 | 7 | 47 | 42 |
Total number of gains: 22; Total number of losses: 189; Total Number of normals: 277.
Somatic mutations of DOK7:
Generating mutation plots.
Highly correlated genes for DOK7:
Showing top 20/177 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DOK7 | TPO | 0.839007 | 3 | 0 | 3 |
| DOK7 | FGFR4 | 0.816271 | 3 | 0 | 3 |
| DOK7 | FGF18 | 0.807612 | 3 | 0 | 3 |
| DOK7 | ORM1 | 0.805031 | 3 | 0 | 3 |
| DOK7 | FOXA3 | 0.801039 | 3 | 0 | 3 |
| DOK7 | SLC30A2 | 0.796936 | 3 | 0 | 3 |
| DOK7 | SYCE3 | 0.792916 | 3 | 0 | 3 |
| DOK7 | GRIN1 | 0.774341 | 3 | 0 | 3 |
| DOK7 | SCN1B | 0.763279 | 3 | 0 | 3 |
| DOK7 | OPTC | 0.746329 | 4 | 0 | 4 |
| DOK7 | CFC1 | 0.745959 | 3 | 0 | 3 |
| DOK7 | EMID1 | 0.740041 | 3 | 0 | 3 |
| DOK7 | OR2H2 | 0.738875 | 3 | 0 | 3 |
| DOK7 | MYL4 | 0.738495 | 3 | 0 | 3 |
| DOK7 | PGPEP1 | 0.737852 | 4 | 0 | 3 |
| DOK7 | REG3A | 0.734083 | 3 | 0 | 3 |
| DOK7 | LRRN4 | 0.733494 | 4 | 0 | 4 |
| DOK7 | F2RL3 | 0.732685 | 4 | 0 | 4 |
| DOK7 | C7orf61 | 0.728974 | 3 | 0 | 3 |
| DOK7 | CHD5 | 0.728533 | 3 | 0 | 3 |
For details and further investigation, click here
