| Full name: hormonally up-regulated Neu-associated kinase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 21q22.11 | ||
| Entrez ID: 30811 | HGNC ID: HGNC:13326 | Ensembl Gene: ENSG00000142149 | OMIM ID: 606532 |
| Drug and gene relationship at DGIdb | |||
Expression of HUNK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HUNK | 30811 | 1555935_s_at | 0.1812 | 0.8121 | |
| GSE20347 | HUNK | 30811 | 219535_at | 0.0177 | 0.8199 | |
| GSE23400 | HUNK | 30811 | 219535_at | -0.1210 | 0.0001 | |
| GSE26886 | HUNK | 30811 | 1555935_s_at | 0.2545 | 0.2302 | |
| GSE29001 | HUNK | 30811 | 219535_at | -0.0104 | 0.9584 | |
| GSE38129 | HUNK | 30811 | 219535_at | -0.0878 | 0.3374 | |
| GSE45670 | HUNK | 30811 | 219535_at | -0.1395 | 0.1725 | |
| GSE53622 | HUNK | 30811 | 49835 | 0.2144 | 0.1219 | |
| GSE53624 | HUNK | 30811 | 49835 | 0.5038 | 0.0000 | |
| GSE63941 | HUNK | 30811 | 1555935_s_at | -1.2522 | 0.0089 | |
| GSE77861 | HUNK | 30811 | 219535_at | -0.0865 | 0.5253 | |
| SRP007169 | HUNK | 30811 | RNAseq | 1.2366 | 0.1207 | |
| SRP064894 | HUNK | 30811 | RNAseq | 0.5227 | 0.0559 | |
| SRP133303 | HUNK | 30811 | RNAseq | 0.5284 | 0.0153 | |
| SRP159526 | HUNK | 30811 | RNAseq | 2.1682 | 0.0004 | |
| SRP193095 | HUNK | 30811 | RNAseq | 0.2618 | 0.0426 | |
| SRP219564 | HUNK | 30811 | RNAseq | 0.7469 | 0.2272 | |
| TCGA | HUNK | 30811 | RNAseq | -0.1099 | 0.5586 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by HUNK expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HUNK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HUNK | 30811 | 2 | 10 | 18 | |
| GSE20123 | HUNK | 30811 | 2 | 10 | 18 | |
| GSE43470 | HUNK | 30811 | 2 | 9 | 32 | |
| GSE46452 | HUNK | 30811 | 1 | 21 | 37 | |
| GSE47630 | HUNK | 30811 | 6 | 17 | 17 | |
| GSE54993 | HUNK | 30811 | 9 | 1 | 60 | |
| GSE54994 | HUNK | 30811 | 1 | 9 | 43 | |
| GSE60625 | HUNK | 30811 | 0 | 0 | 11 | |
| GSE74703 | HUNK | 30811 | 2 | 6 | 28 | |
| GSE74704 | HUNK | 30811 | 1 | 6 | 13 | |
| TCGA | HUNK | 30811 | 8 | 37 | 51 |
Total number of gains: 34; Total number of losses: 126; Total Number of normals: 328.
Somatic mutations of HUNK:
Generating mutation plots.
Highly correlated genes for HUNK:
Showing top 20/524 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HUNK | RASGRP2 | 0.72532 | 3 | 0 | 3 |
| HUNK | SARDH | 0.722814 | 3 | 0 | 3 |
| HUNK | ESR2 | 0.718204 | 3 | 0 | 3 |
| HUNK | ZP2 | 0.714676 | 3 | 0 | 3 |
| HUNK | ARMC4 | 0.714434 | 4 | 0 | 4 |
| HUNK | DNMT3L | 0.711237 | 4 | 0 | 4 |
| HUNK | GALNT8 | 0.70361 | 3 | 0 | 3 |
| HUNK | TCL6 | 0.697984 | 3 | 0 | 3 |
| HUNK | HTR1A | 0.696886 | 3 | 0 | 3 |
| HUNK | PTH | 0.687526 | 3 | 0 | 3 |
| HUNK | SLC2A2 | 0.686453 | 3 | 0 | 3 |
| HUNK | SEMA3D | 0.685101 | 3 | 0 | 3 |
| HUNK | RHAG | 0.683308 | 5 | 0 | 4 |
| HUNK | OR3A2 | 0.681372 | 4 | 0 | 3 |
| HUNK | UNC5C | 0.678232 | 3 | 0 | 3 |
| HUNK | MAPK4 | 0.677564 | 3 | 0 | 3 |
| HUNK | BTN1A1 | 0.676952 | 4 | 0 | 4 |
| HUNK | OR10H1 | 0.673707 | 3 | 0 | 3 |
| HUNK | LZTS1 | 0.672549 | 3 | 0 | 3 |
| HUNK | IL9R | 0.665616 | 4 | 0 | 4 |
For details and further investigation, click here
