| Full name: microtubule associated serine/threonine kinase 3 | Alias Symbol: KIAA0561 | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 23031 | HGNC ID: HGNC:19036 | Ensembl Gene: ENSG00000099308 | OMIM ID: 612258 |
| Drug and gene relationship at DGIdb | |||
Expression of MAST3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAST3 | 23031 | 213045_at | 0.3753 | 0.4212 | |
| GSE20347 | MAST3 | 23031 | 213045_at | 0.0330 | 0.7610 | |
| GSE23400 | MAST3 | 23031 | 213045_at | 0.0039 | 0.9173 | |
| GSE26886 | MAST3 | 23031 | 213045_at | 0.2124 | 0.2015 | |
| GSE29001 | MAST3 | 23031 | 213045_at | 0.3762 | 0.0738 | |
| GSE38129 | MAST3 | 23031 | 213045_at | -0.0250 | 0.8553 | |
| GSE45670 | MAST3 | 23031 | 213045_at | 0.1702 | 0.2444 | |
| GSE53622 | MAST3 | 23031 | 74624 | -0.2686 | 0.0002 | |
| GSE53624 | MAST3 | 23031 | 74624 | -0.5762 | 0.0000 | |
| GSE63941 | MAST3 | 23031 | 213045_at | -0.6680 | 0.0646 | |
| GSE77861 | MAST3 | 23031 | 213045_at | 0.0103 | 0.9364 | |
| GSE97050 | MAST3 | 23031 | A_23_P426196 | -0.0434 | 0.8728 | |
| SRP007169 | MAST3 | 23031 | RNAseq | 0.2338 | 0.6913 | |
| SRP064894 | MAST3 | 23031 | RNAseq | 0.5799 | 0.0019 | |
| SRP133303 | MAST3 | 23031 | RNAseq | -0.3115 | 0.0540 | |
| SRP159526 | MAST3 | 23031 | RNAseq | -0.0882 | 0.7885 | |
| SRP193095 | MAST3 | 23031 | RNAseq | 0.2737 | 0.2153 | |
| SRP219564 | MAST3 | 23031 | RNAseq | 0.3497 | 0.1514 | |
| TCGA | MAST3 | 23031 | RNAseq | -0.1096 | 0.0763 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MAST3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MAST3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAST3 | 23031 | 4 | 4 | 22 | |
| GSE20123 | MAST3 | 23031 | 3 | 2 | 25 | |
| GSE43470 | MAST3 | 23031 | 2 | 6 | 35 | |
| GSE46452 | MAST3 | 23031 | 47 | 1 | 11 | |
| GSE47630 | MAST3 | 23031 | 4 | 8 | 28 | |
| GSE54993 | MAST3 | 23031 | 15 | 4 | 51 | |
| GSE54994 | MAST3 | 23031 | 6 | 13 | 34 | |
| GSE60625 | MAST3 | 23031 | 9 | 0 | 2 | |
| GSE74703 | MAST3 | 23031 | 2 | 4 | 30 | |
| GSE74704 | MAST3 | 23031 | 0 | 2 | 18 | |
| TCGA | MAST3 | 23031 | 17 | 9 | 70 |
Total number of gains: 109; Total number of losses: 53; Total Number of normals: 326.
Somatic mutations of MAST3:
Generating mutation plots.
Highly correlated genes for MAST3:
Showing top 20/91 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAST3 | SHISA8 | 0.700811 | 3 | 0 | 3 |
| MAST3 | PSMB9 | 0.695987 | 3 | 0 | 3 |
| MAST3 | TRAF3IP3 | 0.678797 | 3 | 0 | 3 |
| MAST3 | IL27RA | 0.673419 | 5 | 0 | 4 |
| MAST3 | S1PR4 | 0.666619 | 3 | 0 | 3 |
| MAST3 | FERMT3 | 0.663841 | 4 | 0 | 4 |
| MAST3 | MCF2L | 0.649064 | 4 | 0 | 4 |
| MAST3 | CD27 | 0.646933 | 3 | 0 | 3 |
| MAST3 | POLD1 | 0.638192 | 5 | 0 | 4 |
| MAST3 | ACTR1B | 0.637628 | 3 | 0 | 3 |
| MAST3 | PODXL | 0.629369 | 3 | 0 | 3 |
| MAST3 | PPM1F | 0.625239 | 5 | 0 | 4 |
| MAST3 | APBA2 | 0.624192 | 4 | 0 | 4 |
| MAST3 | FBLN7 | 0.6233 | 4 | 0 | 3 |
| MAST3 | BATF | 0.622582 | 6 | 0 | 4 |
| MAST3 | CD72 | 0.621676 | 6 | 0 | 5 |
| MAST3 | BTK | 0.620757 | 4 | 0 | 3 |
| MAST3 | RGS22 | 0.618906 | 3 | 0 | 3 |
| MAST3 | EMC10 | 0.609696 | 4 | 0 | 3 |
| MAST3 | GPATCH3 | 0.606524 | 3 | 0 | 3 |
For details and further investigation, click here
