| Full name: BAALC binder of MAP3K1 and KLF4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q22.3 | ||
| Entrez ID: 79870 | HGNC ID: HGNC:14333 | Ensembl Gene: ENSG00000164929 | OMIM ID: 606602 |
| Drug and gene relationship at DGIdb | |||
Expression of BAALC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BAALC | 79870 | 222780_s_at | 0.2887 | 0.5802 | |
| GSE20347 | BAALC | 79870 | 218899_s_at | 0.3032 | 0.1014 | |
| GSE23400 | BAALC | 79870 | 218899_s_at | 0.1256 | 0.1460 | |
| GSE26886 | BAALC | 79870 | 222780_s_at | 0.6252 | 0.0004 | |
| GSE29001 | BAALC | 79870 | 218899_s_at | 0.7950 | 0.1258 | |
| GSE38129 | BAALC | 79870 | 218899_s_at | 0.4536 | 0.0400 | |
| GSE45670 | BAALC | 79870 | 222780_s_at | 0.3885 | 0.2471 | |
| GSE53622 | BAALC | 79870 | 134644 | 0.4590 | 0.0012 | |
| GSE53624 | BAALC | 79870 | 134644 | 0.3132 | 0.0018 | |
| GSE63941 | BAALC | 79870 | 222780_s_at | -0.5973 | 0.3039 | |
| GSE77861 | BAALC | 79870 | 222780_s_at | 0.7084 | 0.1810 | |
| GSE97050 | BAALC | 79870 | A_33_P3282973 | -0.1341 | 0.4784 | |
| SRP064894 | BAALC | 79870 | RNAseq | 1.7355 | 0.0000 | |
| SRP133303 | BAALC | 79870 | RNAseq | 0.4807 | 0.0153 | |
| SRP159526 | BAALC | 79870 | RNAseq | 3.7748 | 0.0000 | |
| SRP193095 | BAALC | 79870 | RNAseq | 1.8652 | 0.0000 | |
| SRP219564 | BAALC | 79870 | RNAseq | 3.3425 | 0.0000 | |
| TCGA | BAALC | 79870 | RNAseq | 0.0680 | 0.8410 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by BAALC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BAALC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BAALC | 79870 | 17 | 0 | 13 | |
| GSE20123 | BAALC | 79870 | 18 | 0 | 12 | |
| GSE43470 | BAALC | 79870 | 22 | 0 | 21 | |
| GSE46452 | BAALC | 79870 | 24 | 0 | 35 | |
| GSE47630 | BAALC | 79870 | 24 | 0 | 16 | |
| GSE54993 | BAALC | 79870 | 0 | 20 | 50 | |
| GSE54994 | BAALC | 79870 | 38 | 1 | 14 | |
| GSE60625 | BAALC | 79870 | 0 | 4 | 7 | |
| GSE74703 | BAALC | 79870 | 19 | 0 | 17 | |
| GSE74704 | BAALC | 79870 | 12 | 0 | 8 | |
| TCGA | BAALC | 79870 | 59 | 1 | 36 |
Total number of gains: 233; Total number of losses: 26; Total Number of normals: 229.
Somatic mutations of BAALC:
Generating mutation plots.
Highly correlated genes for BAALC:
Showing top 20/280 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BAALC | DNAH9 | 0.808931 | 3 | 0 | 3 |
| BAALC | DEFB128 | 0.800502 | 3 | 0 | 3 |
| BAALC | DCDC1 | 0.799661 | 3 | 0 | 3 |
| BAALC | KCNH3 | 0.79895 | 3 | 0 | 3 |
| BAALC | KLF17 | 0.782642 | 3 | 0 | 3 |
| BAALC | YY2 | 0.781617 | 3 | 0 | 3 |
| BAALC | STRC | 0.780135 | 3 | 0 | 3 |
| BAALC | TMEM235 | 0.778618 | 3 | 0 | 3 |
| BAALC | FOXE3 | 0.778094 | 4 | 0 | 4 |
| BAALC | OR2A5 | 0.772368 | 3 | 0 | 3 |
| BAALC | SLC52A1 | 0.771828 | 3 | 0 | 3 |
| BAALC | KRTAP10-12 | 0.767679 | 3 | 0 | 3 |
| BAALC | FAM71F1 | 0.765904 | 3 | 0 | 3 |
| BAALC | BBC3 | 0.765337 | 3 | 0 | 3 |
| BAALC | C9orf153 | 0.761047 | 3 | 0 | 3 |
| BAALC | PLA2G2C | 0.756827 | 3 | 0 | 3 |
| BAALC | PRAMEF5 | 0.756384 | 3 | 0 | 3 |
| BAALC | OR2T27 | 0.753831 | 3 | 0 | 3 |
| BAALC | OR10AD1 | 0.751012 | 3 | 0 | 3 |
| BAALC | MRPL57 | 0.745261 | 3 | 0 | 3 |
For details and further investigation, click here
