| Full name: semaphorin 6C | Alias Symbol: KIAA1869 | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 10500 | HGNC ID: HGNC:10740 | Ensembl Gene: ENSG00000143434 | OMIM ID: 609294 |
| Drug and gene relationship at DGIdb | |||
Expression of SEMA6C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEMA6C | 10500 | 208100_x_at | -0.0436 | 0.8845 | |
| GSE20347 | SEMA6C | 10500 | 208100_x_at | -0.1855 | 0.0147 | |
| GSE23400 | SEMA6C | 10500 | 208100_x_at | -0.1731 | 0.0000 | |
| GSE26886 | SEMA6C | 10500 | 208100_x_at | 0.0090 | 0.9639 | |
| GSE29001 | SEMA6C | 10500 | 208100_x_at | -0.3889 | 0.0070 | |
| GSE38129 | SEMA6C | 10500 | 208100_x_at | -0.2690 | 0.0361 | |
| GSE45670 | SEMA6C | 10500 | 208100_x_at | -0.1478 | 0.2362 | |
| GSE53622 | SEMA6C | 10500 | 93106 | -0.1921 | 0.0000 | |
| GSE53624 | SEMA6C | 10500 | 93106 | -0.0957 | 0.1788 | |
| GSE63941 | SEMA6C | 10500 | 208100_x_at | 0.3108 | 0.0287 | |
| GSE77861 | SEMA6C | 10500 | 208100_x_at | -0.1308 | 0.3474 | |
| GSE97050 | SEMA6C | 10500 | A_33_P3284919 | -0.0657 | 0.7921 | |
| SRP007169 | SEMA6C | 10500 | RNAseq | 1.2715 | 0.0691 | |
| SRP064894 | SEMA6C | 10500 | RNAseq | 0.9062 | 0.0003 | |
| SRP133303 | SEMA6C | 10500 | RNAseq | -0.2083 | 0.4837 | |
| SRP159526 | SEMA6C | 10500 | RNAseq | 1.1127 | 0.0615 | |
| SRP193095 | SEMA6C | 10500 | RNAseq | 0.1897 | 0.2966 | |
| SRP219564 | SEMA6C | 10500 | RNAseq | 0.1233 | 0.8278 | |
| TCGA | SEMA6C | 10500 | RNAseq | -0.0446 | 0.7242 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SEMA6C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SEMA6C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEMA6C | 10500 | 14 | 0 | 16 | |
| GSE20123 | SEMA6C | 10500 | 14 | 0 | 16 | |
| GSE43470 | SEMA6C | 10500 | 6 | 1 | 36 | |
| GSE46452 | SEMA6C | 10500 | 2 | 1 | 56 | |
| GSE47630 | SEMA6C | 10500 | 14 | 0 | 26 | |
| GSE54993 | SEMA6C | 10500 | 0 | 4 | 66 | |
| GSE54994 | SEMA6C | 10500 | 15 | 0 | 38 | |
| GSE60625 | SEMA6C | 10500 | 0 | 0 | 11 | |
| GSE74703 | SEMA6C | 10500 | 6 | 1 | 29 | |
| GSE74704 | SEMA6C | 10500 | 7 | 0 | 13 | |
| TCGA | SEMA6C | 10500 | 37 | 2 | 57 |
Total number of gains: 115; Total number of losses: 9; Total Number of normals: 364.
Somatic mutations of SEMA6C:
Generating mutation plots.
Highly correlated genes for SEMA6C:
Showing top 20/664 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEMA6C | IL34 | 0.763789 | 5 | 0 | 5 |
| SEMA6C | SLC25A2 | 0.718471 | 3 | 0 | 3 |
| SEMA6C | ADAM30 | 0.687164 | 5 | 0 | 5 |
| SEMA6C | FMN2 | 0.684004 | 4 | 0 | 4 |
| SEMA6C | SIK1 | 0.683663 | 5 | 0 | 5 |
| SEMA6C | TMEM175 | 0.683107 | 3 | 0 | 3 |
| SEMA6C | SP6 | 0.682531 | 4 | 0 | 4 |
| SEMA6C | CELF3 | 0.680731 | 10 | 0 | 10 |
| SEMA6C | COL26A1 | 0.680412 | 4 | 0 | 3 |
| SEMA6C | CYP11B2 | 0.678201 | 9 | 0 | 8 |
| SEMA6C | SSH3 | 0.673856 | 4 | 0 | 4 |
| SEMA6C | C16orf86 | 0.667011 | 3 | 0 | 3 |
| SEMA6C | DBX1 | 0.666501 | 3 | 0 | 3 |
| SEMA6C | GNAT1 | 0.665642 | 6 | 0 | 5 |
| SEMA6C | TBKBP1 | 0.660317 | 9 | 0 | 8 |
| SEMA6C | MYOG | 0.656112 | 10 | 0 | 10 |
| SEMA6C | CNGB1 | 0.65315 | 8 | 0 | 8 |
| SEMA6C | RPRML | 0.650111 | 4 | 0 | 4 |
| SEMA6C | MYL10 | 0.647608 | 10 | 0 | 8 |
| SEMA6C | ARHGEF15 | 0.645914 | 6 | 0 | 6 |
For details and further investigation, click here
