| Full name: fibronectin type III domain containing 8 | Alias Symbol: DKFZp434H2215 | ||
| Type: protein-coding gene | Cytoband: 17q12 | ||
| Entrez ID: 54752 | HGNC ID: HGNC:25286 | Ensembl Gene: ENSG00000073598 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FNDC8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FNDC8 | 54752 | 220499_at | -0.0983 | 0.6252 | |
| GSE20347 | FNDC8 | 54752 | 220499_at | -0.0540 | 0.4985 | |
| GSE23400 | FNDC8 | 54752 | 220499_at | -0.2347 | 0.0000 | |
| GSE26886 | FNDC8 | 54752 | 220499_at | 0.4392 | 0.0055 | |
| GSE29001 | FNDC8 | 54752 | 220499_at | -0.2256 | 0.1797 | |
| GSE38129 | FNDC8 | 54752 | 220499_at | -0.1393 | 0.0463 | |
| GSE45670 | FNDC8 | 54752 | 220499_at | -0.0157 | 0.9045 | |
| GSE63941 | FNDC8 | 54752 | 220499_at | 0.2929 | 0.0329 | |
| GSE77861 | FNDC8 | 54752 | 220499_at | -0.0733 | 0.5539 | |
| GSE97050 | FNDC8 | 54752 | A_23_P66552 | 0.0486 | 0.8949 | |
| TCGA | FNDC8 | 54752 | RNAseq | 0.3848 | 0.1343 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FNDC8 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of FNDC8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FNDC8 | 54752 | 5 | 1 | 24 | |
| GSE20123 | FNDC8 | 54752 | 5 | 1 | 24 | |
| GSE43470 | FNDC8 | 54752 | 1 | 2 | 40 | |
| GSE46452 | FNDC8 | 54752 | 34 | 0 | 25 | |
| GSE47630 | FNDC8 | 54752 | 7 | 1 | 32 | |
| GSE54993 | FNDC8 | 54752 | 3 | 3 | 64 | |
| GSE54994 | FNDC8 | 54752 | 8 | 6 | 39 | |
| GSE60625 | FNDC8 | 54752 | 4 | 0 | 7 | |
| GSE74703 | FNDC8 | 54752 | 1 | 1 | 34 | |
| GSE74704 | FNDC8 | 54752 | 3 | 1 | 16 | |
| TCGA | FNDC8 | 54752 | 20 | 9 | 67 |
Total number of gains: 91; Total number of losses: 25; Total Number of normals: 372.
Somatic mutations of FNDC8:
Generating mutation plots.
Highly correlated genes for FNDC8:
Showing top 20/854 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FNDC8 | GGN | 0.734717 | 3 | 0 | 3 |
| FNDC8 | NFAM1 | 0.733916 | 3 | 0 | 3 |
| FNDC8 | CNTF | 0.711539 | 3 | 0 | 3 |
| FNDC8 | CA8 | 0.711057 | 3 | 0 | 3 |
| FNDC8 | TMCC3 | 0.710567 | 3 | 0 | 3 |
| FNDC8 | EDA2R | 0.705441 | 5 | 0 | 4 |
| FNDC8 | CABIN1 | 0.700104 | 3 | 0 | 3 |
| FNDC8 | HEYL | 0.695598 | 7 | 0 | 7 |
| FNDC8 | NR1H2 | 0.695071 | 3 | 0 | 3 |
| FNDC8 | ADAM30 | 0.693891 | 5 | 0 | 5 |
| FNDC8 | CACNB1 | 0.689622 | 5 | 0 | 5 |
| FNDC8 | SERPINA6 | 0.686764 | 4 | 0 | 4 |
| FNDC8 | CACNA1S | 0.685029 | 3 | 0 | 3 |
| FNDC8 | TNFRSF4 | 0.684864 | 5 | 0 | 4 |
| FNDC8 | SLC6A5 | 0.684633 | 3 | 0 | 3 |
| FNDC8 | SORBS3 | 0.677987 | 3 | 0 | 3 |
| FNDC8 | MTAP | 0.676103 | 4 | 0 | 4 |
| FNDC8 | CCR10 | 0.675284 | 4 | 0 | 3 |
| FNDC8 | COPE | 0.670954 | 3 | 0 | 3 |
| FNDC8 | GUCY2D | 0.670523 | 3 | 0 | 3 |
For details and further investigation, click here
