| Full name: alpha-methylacyl-CoA racemase | Alias Symbol: RACE|P504S | ||
| Type: protein-coding gene | Cytoband: 5p13.2 | ||
| Entrez ID: 23600 | HGNC ID: HGNC:451 | Ensembl Gene: ENSG00000242110 | OMIM ID: 604489 |
| Drug and gene relationship at DGIdb | |||
Expression of AMACR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AMACR | 23600 | 217113_at | -0.1431 | 0.5859 | |
| GSE20347 | AMACR | 23600 | 217113_at | -0.1254 | 0.0844 | |
| GSE23400 | AMACR | 23600 | 217113_at | -0.2289 | 0.0000 | |
| GSE26886 | AMACR | 23600 | 217113_at | -0.0499 | 0.7218 | |
| GSE29001 | AMACR | 23600 | 217113_at | -0.1368 | 0.3030 | |
| GSE38129 | AMACR | 23600 | 217113_at | -0.2088 | 0.0122 | |
| GSE45670 | AMACR | 23600 | 217111_at | -0.1621 | 0.1574 | |
| GSE63941 | AMACR | 23600 | 217113_at | 0.1449 | 0.4267 | |
| GSE77861 | AMACR | 23600 | 217113_at | -0.1738 | 0.1341 | |
| GSE97050 | AMACR | 23600 | A_33_P3313245 | -0.1884 | 0.5234 | |
| SRP007169 | AMACR | 23600 | RNAseq | -3.3219 | 0.0000 | |
| SRP008496 | AMACR | 23600 | RNAseq | -3.8052 | 0.0000 | |
| SRP064894 | AMACR | 23600 | RNAseq | -1.3759 | 0.0000 | |
| SRP133303 | AMACR | 23600 | RNAseq | -0.7224 | 0.0011 | |
| SRP159526 | AMACR | 23600 | RNAseq | -1.0931 | 0.0506 | |
| SRP193095 | AMACR | 23600 | RNAseq | -1.3188 | 0.0000 | |
| SRP219564 | AMACR | 23600 | RNAseq | -1.1050 | 0.0218 | |
| TCGA | AMACR | 23600 | RNAseq | -0.3921 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by AMACR expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of AMACR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AMACR | 23600 | 11 | 0 | 19 | |
| GSE20123 | AMACR | 23600 | 11 | 0 | 19 | |
| GSE43470 | AMACR | 23600 | 15 | 3 | 25 | |
| GSE46452 | AMACR | 23600 | 6 | 21 | 32 | |
| GSE47630 | AMACR | 23600 | 6 | 12 | 22 | |
| GSE54993 | AMACR | 23600 | 5 | 4 | 61 | |
| GSE54994 | AMACR | 23600 | 26 | 2 | 25 | |
| GSE60625 | AMACR | 23600 | 0 | 0 | 11 | |
| GSE74703 | AMACR | 23600 | 12 | 2 | 22 | |
| GSE74704 | AMACR | 23600 | 10 | 0 | 10 | |
| TCGA | AMACR | 23600 | 52 | 6 | 38 |
Total number of gains: 154; Total number of losses: 50; Total Number of normals: 284.
Somatic mutations of AMACR:
Generating mutation plots.
Highly correlated genes for AMACR:
Showing top 20/880 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AMACR | SLC10A1 | 0.711244 | 5 | 0 | 5 |
| AMACR | ZNF835 | 0.710554 | 4 | 0 | 4 |
| AMACR | DGCR5 | 0.706553 | 3 | 0 | 3 |
| AMACR | MYOD1 | 0.704559 | 3 | 0 | 3 |
| AMACR | SLC6A5 | 0.701699 | 3 | 0 | 3 |
| AMACR | CEND1 | 0.701062 | 4 | 0 | 4 |
| AMACR | ST8SIA3 | 0.692314 | 4 | 0 | 3 |
| AMACR | ADAM30 | 0.688875 | 3 | 0 | 3 |
| AMACR | PDYN | 0.688263 | 5 | 0 | 5 |
| AMACR | SLC12A3 | 0.687076 | 3 | 0 | 3 |
| AMACR | IGH | 0.685216 | 4 | 0 | 4 |
| AMACR | BRINP2 | 0.684818 | 4 | 0 | 4 |
| AMACR | SLC6A11 | 0.682057 | 4 | 0 | 4 |
| AMACR | PSG7 | 0.681739 | 3 | 0 | 3 |
| AMACR | PAPPA2 | 0.681576 | 3 | 0 | 3 |
| AMACR | OTOR | 0.680873 | 4 | 0 | 3 |
| AMACR | ADAMTS13 | 0.680004 | 3 | 0 | 3 |
| AMACR | KCNQ4 | 0.679943 | 5 | 0 | 5 |
| AMACR | KLF1 | 0.678609 | 3 | 0 | 3 |
| AMACR | DCST1 | 0.676263 | 3 | 0 | 3 |
For details and further investigation, click here
