| Full name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 18q21.1 | ||
| Entrez ID: 29906 | HGNC ID: HGNC:17827 | Ensembl Gene: ENSG00000101638 | OMIM ID: 607162 |
| Drug and gene relationship at DGIdb | |||
Expression of ST8SIA5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ST8SIA5 | 29906 | 236110_at | 0.0979 | 0.7531 | |
| GSE20347 | ST8SIA5 | 29906 | 206258_at | -0.0632 | 0.4642 | |
| GSE23400 | ST8SIA5 | 29906 | 206258_at | -0.2085 | 0.0000 | |
| GSE26886 | ST8SIA5 | 29906 | 236110_at | 0.2104 | 0.0687 | |
| GSE29001 | ST8SIA5 | 29906 | 206258_at | -0.0581 | 0.6814 | |
| GSE38129 | ST8SIA5 | 29906 | 217514_at | -0.1217 | 0.0200 | |
| GSE45670 | ST8SIA5 | 29906 | 236110_at | 0.1540 | 0.0747 | |
| GSE53622 | ST8SIA5 | 29906 | 17488 | 0.2221 | 0.0314 | |
| GSE53624 | ST8SIA5 | 29906 | 17488 | 0.3579 | 0.0013 | |
| GSE63941 | ST8SIA5 | 29906 | 236110_at | -0.1958 | 0.0625 | |
| GSE77861 | ST8SIA5 | 29906 | 236110_at | -0.0193 | 0.8962 | |
| SRP133303 | ST8SIA5 | 29906 | RNAseq | 0.0603 | 0.7433 | |
| SRP159526 | ST8SIA5 | 29906 | RNAseq | 0.5577 | 0.2360 | |
| SRP193095 | ST8SIA5 | 29906 | RNAseq | -0.1153 | 0.4334 | |
| SRP219564 | ST8SIA5 | 29906 | RNAseq | 0.2112 | 0.6330 | |
| TCGA | ST8SIA5 | 29906 | RNAseq | -1.1730 | 0.0179 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ST8SIA5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ST8SIA5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ST8SIA5 | 29906 | 1 | 8 | 21 | |
| GSE20123 | ST8SIA5 | 29906 | 1 | 8 | 21 | |
| GSE43470 | ST8SIA5 | 29906 | 0 | 4 | 39 | |
| GSE46452 | ST8SIA5 | 29906 | 1 | 26 | 32 | |
| GSE47630 | ST8SIA5 | 29906 | 5 | 20 | 15 | |
| GSE54993 | ST8SIA5 | 29906 | 8 | 1 | 61 | |
| GSE54994 | ST8SIA5 | 29906 | 3 | 14 | 36 | |
| GSE60625 | ST8SIA5 | 29906 | 0 | 4 | 7 | |
| GSE74703 | ST8SIA5 | 29906 | 0 | 3 | 33 | |
| GSE74704 | ST8SIA5 | 29906 | 0 | 6 | 14 | |
| TCGA | ST8SIA5 | 29906 | 15 | 39 | 42 |
Total number of gains: 34; Total number of losses: 133; Total Number of normals: 321.
Somatic mutations of ST8SIA5:
Generating mutation plots.
Highly correlated genes for ST8SIA5:
Showing top 20/401 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ST8SIA5 | TMCC1-AS1 | 0.714532 | 3 | 0 | 3 |
| ST8SIA5 | ADAM30 | 0.700197 | 3 | 0 | 3 |
| ST8SIA5 | LINC01432 | 0.694549 | 3 | 0 | 3 |
| ST8SIA5 | GTDC1 | 0.670984 | 3 | 0 | 3 |
| ST8SIA5 | FCN2 | 0.670412 | 4 | 0 | 4 |
| ST8SIA5 | PTPRJ | 0.668888 | 4 | 0 | 4 |
| ST8SIA5 | CDK20 | 0.667803 | 3 | 0 | 3 |
| ST8SIA5 | IL9R | 0.657991 | 4 | 0 | 4 |
| ST8SIA5 | PRAMEF10 | 0.656643 | 4 | 0 | 4 |
| ST8SIA5 | MYF5 | 0.655015 | 4 | 0 | 3 |
| ST8SIA5 | SRPK3 | 0.654035 | 4 | 0 | 4 |
| ST8SIA5 | SCTR | 0.653355 | 6 | 0 | 6 |
| ST8SIA5 | SLC39A5 | 0.652013 | 4 | 0 | 4 |
| ST8SIA5 | MYH7 | 0.651542 | 4 | 0 | 3 |
| ST8SIA5 | KCTD19 | 0.650004 | 4 | 0 | 4 |
| ST8SIA5 | HRC | 0.649446 | 3 | 0 | 3 |
| ST8SIA5 | CCDC33 | 0.645097 | 4 | 0 | 3 |
| ST8SIA5 | CECR9 | 0.644847 | 3 | 0 | 3 |
| ST8SIA5 | RORC | 0.641405 | 3 | 0 | 3 |
| ST8SIA5 | IFNA16 | 0.640851 | 4 | 0 | 3 |
For details and further investigation, click here
