| Full name: CDC42 effector protein 5 | Alias Symbol: CEP5|Borg3 | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 148170 | HGNC ID: HGNC:17408 | Ensembl Gene: ENSG00000167617 | OMIM ID: 609171 |
| Drug and gene relationship at DGIdb | |||
Expression of CDC42EP5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDC42EP5 | 148170 | 227850_x_at | -0.6003 | 0.3210 | |
| GSE26886 | CDC42EP5 | 148170 | 227850_x_at | -1.6511 | 0.0052 | |
| GSE45670 | CDC42EP5 | 148170 | 227850_x_at | -0.5733 | 0.1553 | |
| GSE53622 | CDC42EP5 | 148170 | 54620 | 0.0034 | 0.9488 | |
| GSE53624 | CDC42EP5 | 148170 | 54620 | -0.0058 | 0.9272 | |
| GSE63941 | CDC42EP5 | 148170 | 227850_x_at | -2.3104 | 0.0600 | |
| GSE77861 | CDC42EP5 | 148170 | 227850_x_at | -1.5617 | 0.0264 | |
| GSE97050 | CDC42EP5 | 148170 | A_33_P3342235 | 0.2881 | 0.2429 | |
| SRP007169 | CDC42EP5 | 148170 | RNAseq | -2.2246 | 0.0000 | |
| SRP064894 | CDC42EP5 | 148170 | RNAseq | -1.0091 | 0.0306 | |
| SRP133303 | CDC42EP5 | 148170 | RNAseq | -1.1927 | 0.0007 | |
| SRP159526 | CDC42EP5 | 148170 | RNAseq | -1.2079 | 0.0000 | |
| SRP219564 | CDC42EP5 | 148170 | RNAseq | -0.2372 | 0.6237 | |
| TCGA | CDC42EP5 | 148170 | RNAseq | -0.3946 | 0.0030 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by CDC42EP5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDC42EP5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDC42EP5 | 148170 | 3 | 4 | 23 | |
| GSE20123 | CDC42EP5 | 148170 | 3 | 3 | 24 | |
| GSE43470 | CDC42EP5 | 148170 | 2 | 11 | 30 | |
| GSE46452 | CDC42EP5 | 148170 | 45 | 1 | 13 | |
| GSE47630 | CDC42EP5 | 148170 | 8 | 6 | 26 | |
| GSE54993 | CDC42EP5 | 148170 | 17 | 4 | 49 | |
| GSE54994 | CDC42EP5 | 148170 | 4 | 13 | 36 | |
| GSE60625 | CDC42EP5 | 148170 | 9 | 0 | 2 | |
| GSE74703 | CDC42EP5 | 148170 | 2 | 7 | 27 | |
| GSE74704 | CDC42EP5 | 148170 | 3 | 1 | 16 | |
| TCGA | CDC42EP5 | 148170 | 19 | 14 | 63 |
Total number of gains: 115; Total number of losses: 64; Total Number of normals: 309.
Somatic mutations of CDC42EP5:
Generating mutation plots.
Highly correlated genes for CDC42EP5:
Showing top 20/354 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDC42EP5 | AASS | 0.735957 | 3 | 0 | 3 |
| CDC42EP5 | PLAA | 0.716962 | 3 | 0 | 3 |
| CDC42EP5 | MAP4 | 0.714398 | 4 | 0 | 3 |
| CDC42EP5 | RNF125 | 0.700571 | 3 | 0 | 3 |
| CDC42EP5 | ADAMTSL5 | 0.693508 | 4 | 0 | 3 |
| CDC42EP5 | UTS2R | 0.69346 | 3 | 0 | 3 |
| CDC42EP5 | ZNF681 | 0.688055 | 3 | 0 | 3 |
| CDC42EP5 | ENTPD2 | 0.684962 | 3 | 0 | 3 |
| CDC42EP5 | GBP2 | 0.684888 | 3 | 0 | 3 |
| CDC42EP5 | TJP3 | 0.684098 | 4 | 0 | 4 |
| CDC42EP5 | NTN1 | 0.682404 | 4 | 0 | 4 |
| CDC42EP5 | PLEKHG5 | 0.678042 | 3 | 0 | 3 |
| CDC42EP5 | MAP3K8 | 0.675117 | 3 | 0 | 3 |
| CDC42EP5 | SLC11A1 | 0.672315 | 3 | 0 | 3 |
| CDC42EP5 | CAPN3 | 0.670353 | 3 | 0 | 3 |
| CDC42EP5 | PRSS36 | 0.667277 | 3 | 0 | 3 |
| CDC42EP5 | CALY | 0.665614 | 3 | 0 | 3 |
| CDC42EP5 | DUSP22 | 0.661651 | 4 | 0 | 3 |
| CDC42EP5 | FAM3B | 0.656767 | 4 | 0 | 3 |
| CDC42EP5 | COG3 | 0.654563 | 4 | 0 | 4 |
For details and further investigation, click here
