| Full name: crystallin beta B2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q11.23 | ||
| Entrez ID: 1415 | HGNC ID: HGNC:2398 | Ensembl Gene: ENSG00000244752 | OMIM ID: 123620 |
| Drug and gene relationship at DGIdb | |||
Expression of CRYBB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRYBB2 | 1415 | 206778_at | 0.1758 | 0.4567 | |
| GSE20347 | CRYBB2 | 1415 | 206778_at | 0.0805 | 0.4241 | |
| GSE23400 | CRYBB2 | 1415 | 206778_at | 0.0345 | 0.3855 | |
| GSE26886 | CRYBB2 | 1415 | 206778_at | 0.3075 | 0.0464 | |
| GSE29001 | CRYBB2 | 1415 | 206778_at | 0.0457 | 0.8025 | |
| GSE38129 | CRYBB2 | 1415 | 206778_at | -0.0298 | 0.7261 | |
| GSE45670 | CRYBB2 | 1415 | 206778_at | 0.0610 | 0.6005 | |
| GSE53622 | CRYBB2 | 1415 | 5367 | 0.3361 | 0.0000 | |
| GSE53624 | CRYBB2 | 1415 | 5367 | 0.2512 | 0.0237 | |
| GSE63941 | CRYBB2 | 1415 | 206778_at | -0.1611 | 0.4040 | |
| GSE77861 | CRYBB2 | 1415 | 206778_at | -0.0468 | 0.7137 | |
| GSE97050 | CRYBB2 | 1415 | A_23_P425066 | 0.1199 | 0.6159 | |
| TCGA | CRYBB2 | 1415 | RNAseq | 1.7914 | 0.0021 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CRYBB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRYBB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRYBB2 | 1415 | 4 | 6 | 20 | |
| GSE20123 | CRYBB2 | 1415 | 4 | 5 | 21 | |
| GSE43470 | CRYBB2 | 1415 | 3 | 5 | 35 | |
| GSE46452 | CRYBB2 | 1415 | 31 | 1 | 27 | |
| GSE47630 | CRYBB2 | 1415 | 8 | 5 | 27 | |
| GSE54993 | CRYBB2 | 1415 | 3 | 6 | 61 | |
| GSE54994 | CRYBB2 | 1415 | 11 | 7 | 35 | |
| GSE60625 | CRYBB2 | 1415 | 5 | 0 | 6 | |
| GSE74703 | CRYBB2 | 1415 | 3 | 4 | 29 | |
| GSE74704 | CRYBB2 | 1415 | 1 | 3 | 16 | |
| TCGA | CRYBB2 | 1415 | 26 | 14 | 56 |
Total number of gains: 99; Total number of losses: 56; Total Number of normals: 333.
Somatic mutations of CRYBB2:
Generating mutation plots.
Highly correlated genes for CRYBB2:
Showing top 20/481 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRYBB2 | XRRA1 | 0.803306 | 3 | 0 | 3 |
| CRYBB2 | CACNA1B | 0.801697 | 3 | 0 | 3 |
| CRYBB2 | ADAMTSL5 | 0.794074 | 3 | 0 | 3 |
| CRYBB2 | TRAF2 | 0.789613 | 3 | 0 | 3 |
| CRYBB2 | TNPO1 | 0.77235 | 3 | 0 | 3 |
| CRYBB2 | DNHD1 | 0.770669 | 3 | 0 | 3 |
| CRYBB2 | ATF7 | 0.764199 | 3 | 0 | 3 |
| CRYBB2 | ISM2 | 0.759186 | 3 | 0 | 3 |
| CRYBB2 | SEMA4C | 0.749623 | 3 | 0 | 3 |
| CRYBB2 | RARA | 0.746887 | 5 | 0 | 5 |
| CRYBB2 | YWHAG | 0.744614 | 3 | 0 | 3 |
| CRYBB2 | PVRIG | 0.741631 | 3 | 0 | 3 |
| CRYBB2 | SLC25A29 | 0.73793 | 3 | 0 | 3 |
| CRYBB2 | AAK1 | 0.737085 | 3 | 0 | 3 |
| CRYBB2 | RELL2 | 0.730721 | 3 | 0 | 3 |
| CRYBB2 | EVI5L | 0.730065 | 4 | 0 | 4 |
| CRYBB2 | PLIN4 | 0.729072 | 3 | 0 | 3 |
| CRYBB2 | DOC2B | 0.72868 | 3 | 0 | 3 |
| CRYBB2 | CLMN | 0.728214 | 3 | 0 | 3 |
| CRYBB2 | EXOC3L1 | 0.726235 | 3 | 0 | 3 |
For details and further investigation, click here
