| Full name: adiponectin receptor 1 | Alias Symbol: PAQR1|ACDCR1 | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 51094 | HGNC ID: HGNC:24040 | Ensembl Gene: ENSG00000159346 | OMIM ID: 607945 |
| Drug and gene relationship at DGIdb | |||
ADIPOR1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04152 | AMPK signaling pathway | |
| hsa04211 | Longevity regulating pathway - mammal | |
| hsa04920 | Adipocytokine signaling pathway | |
| hsa04932 | Non-alcoholic fatty liver disease (NAFLD) |
Expression of ADIPOR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADIPOR1 | 51094 | 217748_at | 0.0346 | 0.9510 | |
| GSE20347 | ADIPOR1 | 51094 | 217748_at | -0.7321 | 0.0000 | |
| GSE23400 | ADIPOR1 | 51094 | 217748_at | -0.3181 | 0.0000 | |
| GSE26886 | ADIPOR1 | 51094 | 217748_at | -1.5925 | 0.0000 | |
| GSE29001 | ADIPOR1 | 51094 | 217748_at | -0.5507 | 0.0292 | |
| GSE38129 | ADIPOR1 | 51094 | 217748_at | -0.3897 | 0.0281 | |
| GSE45670 | ADIPOR1 | 51094 | 217748_at | -0.3149 | 0.0442 | |
| GSE53622 | ADIPOR1 | 51094 | 42071 | -0.5097 | 0.0000 | |
| GSE53624 | ADIPOR1 | 51094 | 17485 | -0.5818 | 0.0000 | |
| GSE63941 | ADIPOR1 | 51094 | 217748_at | 0.4118 | 0.2001 | |
| GSE77861 | ADIPOR1 | 51094 | 217748_at | -0.3692 | 0.0023 | |
| GSE97050 | ADIPOR1 | 51094 | A_33_P3248765 | -0.0794 | 0.8706 | |
| SRP007169 | ADIPOR1 | 51094 | RNAseq | -2.4968 | 0.0000 | |
| SRP008496 | ADIPOR1 | 51094 | RNAseq | -2.1373 | 0.0000 | |
| SRP064894 | ADIPOR1 | 51094 | RNAseq | -1.2101 | 0.0000 | |
| SRP133303 | ADIPOR1 | 51094 | RNAseq | -0.5509 | 0.0037 | |
| SRP159526 | ADIPOR1 | 51094 | RNAseq | -0.5889 | 0.1022 | |
| SRP193095 | ADIPOR1 | 51094 | RNAseq | -0.8584 | 0.0000 | |
| SRP219564 | ADIPOR1 | 51094 | RNAseq | -0.9409 | 0.0647 | |
| TCGA | ADIPOR1 | 51094 | RNAseq | 0.0254 | 0.5473 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by ADIPOR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADIPOR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADIPOR1 | 51094 | 11 | 0 | 19 | |
| GSE20123 | ADIPOR1 | 51094 | 11 | 0 | 19 | |
| GSE43470 | ADIPOR1 | 51094 | 6 | 0 | 37 | |
| GSE46452 | ADIPOR1 | 51094 | 3 | 1 | 55 | |
| GSE47630 | ADIPOR1 | 51094 | 14 | 0 | 26 | |
| GSE54993 | ADIPOR1 | 51094 | 0 | 6 | 64 | |
| GSE54994 | ADIPOR1 | 51094 | 15 | 0 | 38 | |
| GSE60625 | ADIPOR1 | 51094 | 0 | 0 | 11 | |
| GSE74703 | ADIPOR1 | 51094 | 6 | 0 | 30 | |
| GSE74704 | ADIPOR1 | 51094 | 5 | 0 | 15 | |
| TCGA | ADIPOR1 | 51094 | 44 | 4 | 48 |
Total number of gains: 115; Total number of losses: 11; Total Number of normals: 362.
Somatic mutations of ADIPOR1:
Generating mutation plots.
Highly correlated genes for ADIPOR1:
Showing top 20/1402 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADIPOR1 | TMEM234 | 0.762355 | 3 | 0 | 3 |
| ADIPOR1 | FAM214A | 0.756955 | 5 | 0 | 5 |
| ADIPOR1 | C5orf66-AS1 | 0.755772 | 5 | 0 | 5 |
| ADIPOR1 | SNORA68 | 0.752241 | 3 | 0 | 3 |
| ADIPOR1 | VSIG10L | 0.74603 | 5 | 0 | 5 |
| ADIPOR1 | KLB | 0.741668 | 5 | 0 | 5 |
| ADIPOR1 | FAM83G | 0.737415 | 3 | 0 | 3 |
| ADIPOR1 | WDR26 | 0.734312 | 12 | 0 | 12 |
| ADIPOR1 | GRPEL2 | 0.7339 | 7 | 0 | 7 |
| ADIPOR1 | RASSF5 | 0.733779 | 8 | 0 | 7 |
| ADIPOR1 | ULK3 | 0.731252 | 7 | 0 | 7 |
| ADIPOR1 | ZNF431 | 0.727088 | 5 | 0 | 5 |
| ADIPOR1 | S100A16 | 0.723024 | 8 | 0 | 7 |
| ADIPOR1 | SH3GL1 | 0.722907 | 11 | 0 | 11 |
| ADIPOR1 | SCNN1B | 0.722689 | 9 | 0 | 9 |
| ADIPOR1 | MPZL3 | 0.719877 | 8 | 0 | 7 |
| ADIPOR1 | NUAK2 | 0.717199 | 3 | 0 | 3 |
| ADIPOR1 | TAB3 | 0.716234 | 7 | 0 | 7 |
| ADIPOR1 | TMEM154 | 0.716089 | 6 | 0 | 6 |
| ADIPOR1 | PRSS27 | 0.715278 | 6 | 0 | 5 |
For details and further investigation, click here
