| Full name: transmembrane protein 154 | Alias Symbol: FLJ32028 | ||
| Type: protein-coding gene | Cytoband: 4q31.3 | ||
| Entrez ID: 201799 | HGNC ID: HGNC:26489 | Ensembl Gene: ENSG00000170006 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM154:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM154 | 201799 | 238063_at | -1.2710 | 0.3095 | |
| GSE26886 | TMEM154 | 201799 | 238063_at | -2.6263 | 0.0000 | |
| GSE45670 | TMEM154 | 201799 | 238063_at | -0.4609 | 0.0738 | |
| GSE53622 | TMEM154 | 201799 | 6868 | -1.8434 | 0.0000 | |
| GSE53624 | TMEM154 | 201799 | 6868 | -1.8582 | 0.0000 | |
| GSE63941 | TMEM154 | 201799 | 238063_at | -0.0877 | 0.9332 | |
| GSE77861 | TMEM154 | 201799 | 238063_at | -1.4292 | 0.0064 | |
| GSE97050 | TMEM154 | 201799 | A_33_P3314031 | -0.1436 | 0.8834 | |
| SRP007169 | TMEM154 | 201799 | RNAseq | -0.9179 | 0.0960 | |
| SRP008496 | TMEM154 | 201799 | RNAseq | -1.2862 | 0.0024 | |
| SRP064894 | TMEM154 | 201799 | RNAseq | -2.1186 | 0.0000 | |
| SRP133303 | TMEM154 | 201799 | RNAseq | -1.1752 | 0.0000 | |
| SRP159526 | TMEM154 | 201799 | RNAseq | -2.5380 | 0.0000 | |
| SRP193095 | TMEM154 | 201799 | RNAseq | -1.5392 | 0.0000 | |
| SRP219564 | TMEM154 | 201799 | RNAseq | -2.5257 | 0.0068 | |
| TCGA | TMEM154 | 201799 | RNAseq | 0.7357 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by TMEM154 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM154:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM154 | 201799 | 0 | 14 | 16 | |
| GSE20123 | TMEM154 | 201799 | 0 | 14 | 16 | |
| GSE43470 | TMEM154 | 201799 | 0 | 14 | 29 | |
| GSE46452 | TMEM154 | 201799 | 1 | 36 | 22 | |
| GSE47630 | TMEM154 | 201799 | 0 | 23 | 17 | |
| GSE54993 | TMEM154 | 201799 | 10 | 0 | 60 | |
| GSE54994 | TMEM154 | 201799 | 1 | 13 | 39 | |
| GSE60625 | TMEM154 | 201799 | 0 | 1 | 10 | |
| GSE74703 | TMEM154 | 201799 | 0 | 12 | 24 | |
| GSE74704 | TMEM154 | 201799 | 0 | 7 | 13 | |
| TCGA | TMEM154 | 201799 | 10 | 36 | 50 |
Total number of gains: 22; Total number of losses: 170; Total Number of normals: 296.
Somatic mutations of TMEM154:
Generating mutation plots.
Highly correlated genes for TMEM154:
Showing top 20/1358 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM154 | CYSRT1 | 0.875584 | 6 | 0 | 6 |
| TMEM154 | TTC22 | 0.857461 | 7 | 0 | 7 |
| TMEM154 | CAPN14 | 0.854091 | 6 | 0 | 6 |
| TMEM154 | CRCT1 | 0.843062 | 7 | 0 | 7 |
| TMEM154 | ANXA1 | 0.840571 | 8 | 0 | 8 |
| TMEM154 | C15orf48 | 0.838058 | 7 | 0 | 7 |
| TMEM154 | EPS8L2 | 0.836385 | 7 | 0 | 7 |
| TMEM154 | IL1RN | 0.832676 | 8 | 0 | 7 |
| TMEM154 | BTBD11 | 0.830886 | 7 | 0 | 7 |
| TMEM154 | PADI1 | 0.830793 | 4 | 0 | 4 |
| TMEM154 | CWH43 | 0.830242 | 6 | 0 | 6 |
| TMEM154 | TRIP10 | 0.830192 | 6 | 0 | 6 |
| TMEM154 | C1orf116 | 0.829839 | 8 | 0 | 8 |
| TMEM154 | VSIG10L | 0.829252 | 7 | 0 | 7 |
| TMEM154 | EVPL | 0.82849 | 8 | 0 | 7 |
| TMEM154 | TIAM1 | 0.827362 | 6 | 0 | 6 |
| TMEM154 | SH3GL1 | 0.825494 | 6 | 0 | 6 |
| TMEM154 | CEACAM5 | 0.824944 | 7 | 0 | 7 |
| TMEM154 | S100A16 | 0.823957 | 8 | 0 | 7 |
| TMEM154 | MALL | 0.821688 | 9 | 0 | 8 |
For details and further investigation, click here
