| Full name: TGF-beta activated kinase 1 (MAP3K7) binding protein 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: Xp21.2 | ||
| Entrez ID: 257397 | HGNC ID: HGNC:30681 | Ensembl Gene: ENSG00000157625 | OMIM ID: 300480 |
| Drug and gene relationship at DGIdb | |||
TAB3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04064 | NF-kappa B signaling pathway | |
| hsa04621 | NOD-like receptor signaling pathway |
Expression of TAB3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAB3 | 257397 | 227357_at | -0.4864 | 0.4408 | |
| GSE26886 | TAB3 | 257397 | 227357_at | -1.9459 | 0.0000 | |
| GSE45670 | TAB3 | 257397 | 227357_at | -0.4844 | 0.0624 | |
| GSE53622 | TAB3 | 257397 | 32536 | -1.0019 | 0.0000 | |
| GSE53624 | TAB3 | 257397 | 32536 | -1.3367 | 0.0000 | |
| GSE63941 | TAB3 | 257397 | 227357_at | -0.5564 | 0.5910 | |
| GSE77861 | TAB3 | 257397 | 227357_at | -1.1719 | 0.0071 | |
| GSE97050 | TAB3 | 257397 | A_32_P162150 | -0.6201 | 0.1920 | |
| SRP007169 | TAB3 | 257397 | RNAseq | -2.7909 | 0.0000 | |
| SRP008496 | TAB3 | 257397 | RNAseq | -2.5163 | 0.0000 | |
| SRP064894 | TAB3 | 257397 | RNAseq | -1.9638 | 0.0000 | |
| SRP133303 | TAB3 | 257397 | RNAseq | -0.6794 | 0.0025 | |
| SRP159526 | TAB3 | 257397 | RNAseq | -1.2437 | 0.0001 | |
| SRP193095 | TAB3 | 257397 | RNAseq | -1.2624 | 0.0000 | |
| SRP219564 | TAB3 | 257397 | RNAseq | -0.9679 | 0.1295 | |
| TCGA | TAB3 | 257397 | RNAseq | -0.1269 | 0.0526 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by TAB3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAB3:
No record found for this gene.
Somatic mutations of TAB3:
Generating mutation plots.
Highly correlated genes for TAB3:
Showing top 20/1727 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAB3 | C18orf25 | 0.865058 | 7 | 0 | 7 |
| TAB3 | RAB11A | 0.858455 | 7 | 0 | 7 |
| TAB3 | CA13 | 0.849831 | 3 | 0 | 3 |
| TAB3 | TJP1 | 0.844176 | 7 | 0 | 7 |
| TAB3 | USP6NL | 0.843651 | 7 | 0 | 7 |
| TAB3 | ACAA1 | 0.830662 | 4 | 0 | 4 |
| TAB3 | CCNG2 | 0.828253 | 7 | 0 | 7 |
| TAB3 | RNF141 | 0.827367 | 7 | 0 | 7 |
| TAB3 | HDHD2 | 0.82229 | 4 | 0 | 4 |
| TAB3 | SOCS6 | 0.82169 | 5 | 0 | 5 |
| TAB3 | SASH1 | 0.819073 | 7 | 0 | 7 |
| TAB3 | BLNK | 0.818929 | 7 | 0 | 7 |
| TAB3 | NPAS2 | 0.817058 | 4 | 0 | 4 |
| TAB3 | VPS4B | 0.816608 | 7 | 0 | 7 |
| TAB3 | SCP2 | 0.814928 | 7 | 0 | 7 |
| TAB3 | FRMD4B | 0.806616 | 7 | 0 | 7 |
| TAB3 | RANBP9 | 0.804031 | 7 | 0 | 7 |
| TAB3 | MAL | 0.800891 | 6 | 0 | 6 |
| TAB3 | CTTNBP2NL | 0.796803 | 7 | 0 | 7 |
| TAB3 | ABHD5 | 0.795162 | 7 | 0 | 7 |
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