| Full name: GrpE like 2, mitochondrial | Alias Symbol: DKFZp451C205|Mt-GrpE#2|FLJ23713 | ||
| Type: protein-coding gene | Cytoband: 5q32 | ||
| Entrez ID: 134266 | HGNC ID: HGNC:21060 | Ensembl Gene: ENSG00000164284 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of GRPEL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GRPEL2 | 134266 | 226881_at | -0.6205 | 0.6128 | |
| GSE26886 | GRPEL2 | 134266 | 226881_at | -2.9292 | 0.0000 | |
| GSE45670 | GRPEL2 | 134266 | 226881_at | -0.5082 | 0.1355 | |
| GSE53622 | GRPEL2 | 134266 | 41162 | -1.4207 | 0.0000 | |
| GSE53624 | GRPEL2 | 134266 | 41162 | -1.9795 | 0.0000 | |
| GSE63941 | GRPEL2 | 134266 | 226881_at | 0.3120 | 0.6456 | |
| GSE77861 | GRPEL2 | 134266 | 226881_at | -1.5573 | 0.0056 | |
| GSE97050 | GRPEL2 | 134266 | A_23_P404091 | -0.2706 | 0.7085 | |
| SRP007169 | GRPEL2 | 134266 | RNAseq | -3.8628 | 0.0000 | |
| SRP008496 | GRPEL2 | 134266 | RNAseq | -4.1478 | 0.0000 | |
| SRP064894 | GRPEL2 | 134266 | RNAseq | -2.7713 | 0.0000 | |
| SRP133303 | GRPEL2 | 134266 | RNAseq | -1.8370 | 0.0000 | |
| SRP159526 | GRPEL2 | 134266 | RNAseq | -1.9691 | 0.0000 | |
| SRP193095 | GRPEL2 | 134266 | RNAseq | -2.9781 | 0.0000 | |
| SRP219564 | GRPEL2 | 134266 | RNAseq | -2.7452 | 0.0011 | |
| TCGA | GRPEL2 | 134266 | RNAseq | 0.0962 | 0.2722 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by GRPEL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GRPEL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GRPEL2 | 134266 | 1 | 12 | 17 | |
| GSE20123 | GRPEL2 | 134266 | 1 | 12 | 17 | |
| GSE43470 | GRPEL2 | 134266 | 2 | 10 | 31 | |
| GSE46452 | GRPEL2 | 134266 | 0 | 27 | 32 | |
| GSE47630 | GRPEL2 | 134266 | 0 | 20 | 20 | |
| GSE54993 | GRPEL2 | 134266 | 9 | 1 | 60 | |
| GSE54994 | GRPEL2 | 134266 | 2 | 15 | 36 | |
| GSE60625 | GRPEL2 | 134266 | 0 | 0 | 11 | |
| GSE74703 | GRPEL2 | 134266 | 2 | 7 | 27 | |
| GSE74704 | GRPEL2 | 134266 | 1 | 7 | 12 | |
| TCGA | GRPEL2 | 134266 | 6 | 38 | 52 |
Total number of gains: 24; Total number of losses: 149; Total Number of normals: 315.
Somatic mutations of GRPEL2:
Generating mutation plots.
Highly correlated genes for GRPEL2:
Showing top 20/1580 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GRPEL2 | RANBP9 | 0.861282 | 7 | 0 | 7 |
| GRPEL2 | PCBP1-AS1 | 0.841297 | 3 | 0 | 3 |
| GRPEL2 | VPS4B | 0.839423 | 7 | 0 | 7 |
| GRPEL2 | SPNS2 | 0.838782 | 5 | 0 | 5 |
| GRPEL2 | IL22RA1 | 0.837827 | 4 | 0 | 4 |
| GRPEL2 | GYS2 | 0.835567 | 6 | 0 | 6 |
| GRPEL2 | PRSS27 | 0.833008 | 6 | 0 | 6 |
| GRPEL2 | CYSRT1 | 0.829882 | 6 | 0 | 6 |
| GRPEL2 | SCEL | 0.828693 | 6 | 0 | 6 |
| GRPEL2 | ECM1 | 0.828364 | 6 | 0 | 6 |
| GRPEL2 | SULT2B1 | 0.825 | 4 | 0 | 4 |
| GRPEL2 | ARHGAP27 | 0.822828 | 7 | 0 | 7 |
| GRPEL2 | SLC16A6 | 0.818636 | 7 | 0 | 7 |
| GRPEL2 | MXD1 | 0.817787 | 7 | 0 | 7 |
| GRPEL2 | ATG9B | 0.81755 | 7 | 0 | 7 |
| GRPEL2 | PHACTR4 | 0.8171 | 7 | 0 | 7 |
| GRPEL2 | FCHO2 | 0.816527 | 7 | 0 | 7 |
| GRPEL2 | ABHD5 | 0.815646 | 7 | 0 | 7 |
| GRPEL2 | WWC1 | 0.81482 | 7 | 0 | 7 |
| GRPEL2 | TMEM40 | 0.812516 | 7 | 0 | 7 |
For details and further investigation, click here
