| Full name: myelin protein zero like 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q23.3 | ||
| Entrez ID: 196264 | HGNC ID: HGNC:27279 | Ensembl Gene: ENSG00000160588 | OMIM ID: 611707 |
| Drug and gene relationship at DGIdb | |||
Expression of MPZL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MPZL3 | 196264 | 227747_at | -0.8502 | 0.4831 | |
| GSE26886 | MPZL3 | 196264 | 227747_at | -3.7876 | 0.0000 | |
| GSE45670 | MPZL3 | 196264 | 227747_at | -0.5756 | 0.1120 | |
| GSE53622 | MPZL3 | 196264 | 81418 | -1.7250 | 0.0000 | |
| GSE53624 | MPZL3 | 196264 | 128643 | -2.1120 | 0.0000 | |
| GSE63941 | MPZL3 | 196264 | 227747_at | 2.8394 | 0.0009 | |
| GSE77861 | MPZL3 | 196264 | 227747_at | -1.1787 | 0.0029 | |
| GSE97050 | MPZL3 | 196264 | A_24_P270033 | -1.0204 | 0.1967 | |
| SRP007169 | MPZL3 | 196264 | RNAseq | -4.4369 | 0.0000 | |
| SRP008496 | MPZL3 | 196264 | RNAseq | -3.5080 | 0.0000 | |
| SRP064894 | MPZL3 | 196264 | RNAseq | -2.6463 | 0.0000 | |
| SRP133303 | MPZL3 | 196264 | RNAseq | -1.9889 | 0.0000 | |
| SRP159526 | MPZL3 | 196264 | RNAseq | -2.8232 | 0.0000 | |
| SRP193095 | MPZL3 | 196264 | RNAseq | -2.3109 | 0.0000 | |
| SRP219564 | MPZL3 | 196264 | RNAseq | -2.9133 | 0.0019 | |
| TCGA | MPZL3 | 196264 | RNAseq | 0.0192 | 0.9207 |
Upregulated datasets: 1; Downregulated datasets: 11.
Survival by MPZL3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MPZL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MPZL3 | 196264 | 2 | 11 | 17 | |
| GSE20123 | MPZL3 | 196264 | 2 | 11 | 17 | |
| GSE43470 | MPZL3 | 196264 | 2 | 9 | 32 | |
| GSE46452 | MPZL3 | 196264 | 3 | 26 | 30 | |
| GSE47630 | MPZL3 | 196264 | 2 | 19 | 19 | |
| GSE54993 | MPZL3 | 196264 | 10 | 0 | 60 | |
| GSE54994 | MPZL3 | 196264 | 6 | 19 | 28 | |
| GSE60625 | MPZL3 | 196264 | 0 | 3 | 8 | |
| GSE74703 | MPZL3 | 196264 | 1 | 6 | 29 | |
| GSE74704 | MPZL3 | 196264 | 1 | 7 | 12 | |
| TCGA | MPZL3 | 196264 | 6 | 49 | 41 |
Total number of gains: 35; Total number of losses: 160; Total Number of normals: 293.
Somatic mutations of MPZL3:
Generating mutation plots.
Highly correlated genes for MPZL3:
Showing top 20/1461 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MPZL3 | ATG9B | 0.873571 | 7 | 0 | 7 |
| MPZL3 | ARHGAP27 | 0.865932 | 8 | 0 | 8 |
| MPZL3 | PRSS2 | 0.859895 | 4 | 0 | 4 |
| MPZL3 | RANBP9 | 0.85784 | 7 | 0 | 7 |
| MPZL3 | RAET1E | 0.849204 | 6 | 0 | 6 |
| MPZL3 | SLURP1 | 0.847566 | 6 | 0 | 6 |
| MPZL3 | NIPAL1 | 0.847335 | 3 | 0 | 3 |
| MPZL3 | VSIG10L | 0.847062 | 6 | 0 | 6 |
| MPZL3 | CLIC3 | 0.844187 | 5 | 0 | 5 |
| MPZL3 | STRN | 0.840675 | 7 | 0 | 7 |
| MPZL3 | NUAK2 | 0.839287 | 3 | 0 | 3 |
| MPZL3 | TOM1 | 0.836975 | 7 | 0 | 7 |
| MPZL3 | TTC9 | 0.829909 | 7 | 0 | 7 |
| MPZL3 | PRSS27 | 0.828518 | 7 | 0 | 7 |
| MPZL3 | ATP13A4 | 0.828456 | 7 | 0 | 7 |
| MPZL3 | RAB10 | 0.827484 | 7 | 0 | 7 |
| MPZL3 | EPHA1 | 0.825719 | 7 | 0 | 7 |
| MPZL3 | ULK3 | 0.825235 | 7 | 0 | 7 |
| MPZL3 | RAB25 | 0.822453 | 8 | 0 | 8 |
| MPZL3 | DUSP5 | 0.821638 | 7 | 0 | 7 |
For details and further investigation, click here
