| Full name: argonaute RISC component 4 | Alias Symbol: hAGO4|KIAA1567|FLJ20033 | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 192670 | HGNC ID: HGNC:18424 | Ensembl Gene: ENSG00000134698 | OMIM ID: 607356 |
Expression of AGO4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AGO4 | 192670 | 227930_at | -0.7140 | 0.0506 | |
| GSE20347 | AGO4 | 192670 | 219190_s_at | -0.1770 | 0.0444 | |
| GSE23400 | AGO4 | 192670 | 219190_s_at | -0.1274 | 0.0004 | |
| GSE26886 | AGO4 | 192670 | 227930_at | -0.1497 | 0.7461 | |
| GSE29001 | AGO4 | 192670 | 219190_s_at | -0.8135 | 0.0003 | |
| GSE38129 | AGO4 | 192670 | 219190_s_at | -0.4380 | 0.0001 | |
| GSE45670 | AGO4 | 192670 | 227930_at | -0.4612 | 0.0158 | |
| GSE53622 | AGO4 | 192670 | 56178 | -0.8088 | 0.0000 | |
| GSE53624 | AGO4 | 192670 | 56178 | -0.7825 | 0.0000 | |
| GSE63941 | AGO4 | 192670 | 227930_at | -0.2628 | 0.6542 | |
| GSE77861 | AGO4 | 192670 | 227930_at | 0.4609 | 0.2540 | |
| SRP007169 | AGO4 | 192670 | RNAseq | 0.2397 | 0.6542 | |
| SRP008496 | AGO4 | 192670 | RNAseq | 0.9235 | 0.0145 | |
| SRP064894 | AGO4 | 192670 | RNAseq | -0.1393 | 0.4844 | |
| SRP133303 | AGO4 | 192670 | RNAseq | -0.1312 | 0.3727 | |
| SRP159526 | AGO4 | 192670 | RNAseq | -0.2675 | 0.1522 | |
| SRP193095 | AGO4 | 192670 | RNAseq | -0.2064 | 0.0519 | |
| SRP219564 | AGO4 | 192670 | RNAseq | -0.6247 | 0.0861 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AGO4 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of AGO4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AGO4 | 192670 | 2 | 5 | 23 | |
| GSE20123 | AGO4 | 192670 | 2 | 4 | 24 | |
| GSE43470 | AGO4 | 192670 | 7 | 2 | 34 | |
| GSE46452 | AGO4 | 192670 | 4 | 1 | 54 | |
| GSE47630 | AGO4 | 192670 | 8 | 3 | 29 | |
| GSE54993 | AGO4 | 192670 | 1 | 1 | 68 | |
| GSE54994 | AGO4 | 192670 | 11 | 2 | 40 | |
| GSE60625 | AGO4 | 192670 | 0 | 0 | 11 | |
| GSE74703 | AGO4 | 192670 | 6 | 1 | 29 | |
| GSE74704 | AGO4 | 192670 | 1 | 0 | 19 | |
| TCGA | AGO4 | 192670 | 11 | 19 | 66 |
Total number of gains: 53; Total number of losses: 38; Total Number of normals: 397.
Somatic mutations of AGO4:
Generating mutation plots.
Highly correlated genes for AGO4:
Showing top 20/507 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AGO4 | ZCWPW2 | 0.76897 | 3 | 0 | 3 |
| AGO4 | KBTBD3 | 0.736685 | 3 | 0 | 3 |
| AGO4 | COL28A1 | 0.694589 | 3 | 0 | 3 |
| AGO4 | ANO5 | 0.694147 | 4 | 0 | 4 |
| AGO4 | ZC3H6 | 0.675259 | 5 | 0 | 5 |
| AGO4 | ATP10B | 0.670695 | 3 | 0 | 3 |
| AGO4 | KLHL15 | 0.665621 | 5 | 0 | 4 |
| AGO4 | RAB9B | 0.659795 | 4 | 0 | 4 |
| AGO4 | BHMT2 | 0.658056 | 6 | 0 | 6 |
| AGO4 | LINC01082 | 0.65758 | 4 | 0 | 3 |
| AGO4 | PGRMC2 | 0.656019 | 8 | 0 | 7 |
| AGO4 | SHROOM3 | 0.654366 | 3 | 0 | 3 |
| AGO4 | COBL | 0.645818 | 7 | 0 | 6 |
| AGO4 | C1QTNF7 | 0.645423 | 4 | 0 | 3 |
| AGO4 | TMEM59 | 0.644812 | 4 | 0 | 4 |
| AGO4 | NFASC | 0.644693 | 5 | 0 | 4 |
| AGO4 | RAP1A | 0.643336 | 7 | 0 | 6 |
| AGO4 | MYOM1 | 0.643011 | 6 | 0 | 4 |
| AGO4 | PCMTD1 | 0.642443 | 4 | 0 | 3 |
| AGO4 | MYRIP | 0.638144 | 8 | 0 | 7 |
For details and further investigation, click here
