| Full name: myosin VIIA and Rab interacting protein | Alias Symbol: DKFZp586F1018|exophilin-8|MyRIP|SLAC2-C|SLAC2C | ||
| Type: protein-coding gene | Cytoband: 3p22.1 | ||
| Entrez ID: 25924 | HGNC ID: HGNC:19156 | Ensembl Gene: ENSG00000170011 | OMIM ID: 611790 |
| Drug and gene relationship at DGIdb | |||
Expression of MYRIP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYRIP | 25924 | 214156_at | -1.6738 | 0.0151 | |
| GSE20347 | MYRIP | 25924 | 214156_at | -0.4498 | 0.0000 | |
| GSE23400 | MYRIP | 25924 | 214156_at | -0.0824 | 0.0000 | |
| GSE26886 | MYRIP | 25924 | 214156_at | -0.4912 | 0.0113 | |
| GSE29001 | MYRIP | 25924 | 214156_at | -0.4438 | 0.0006 | |
| GSE38129 | MYRIP | 25924 | 214156_at | -1.1111 | 0.0000 | |
| GSE45670 | MYRIP | 25924 | 214156_at | -1.7864 | 0.0000 | |
| GSE53622 | MYRIP | 25924 | 91755 | -3.7136 | 0.0000 | |
| GSE53624 | MYRIP | 25924 | 91755 | -3.5439 | 0.0000 | |
| GSE63941 | MYRIP | 25924 | 214156_at | 0.3251 | 0.5594 | |
| GSE77861 | MYRIP | 25924 | 214156_at | -0.0970 | 0.2445 | |
| GSE97050 | MYRIP | 25924 | A_23_P326760 | -0.6397 | 0.1560 | |
| SRP064894 | MYRIP | 25924 | RNAseq | -1.6331 | 0.0015 | |
| SRP133303 | MYRIP | 25924 | RNAseq | -2.2907 | 0.0000 | |
| SRP159526 | MYRIP | 25924 | RNAseq | -1.7789 | 0.0360 | |
| SRP193095 | MYRIP | 25924 | RNAseq | -0.3604 | 0.2938 | |
| SRP219564 | MYRIP | 25924 | RNAseq | -1.3724 | 0.0741 | |
| TCGA | MYRIP | 25924 | RNAseq | -2.9298 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by MYRIP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MYRIP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYRIP | 25924 | 0 | 19 | 11 | |
| GSE20123 | MYRIP | 25924 | 0 | 19 | 11 | |
| GSE43470 | MYRIP | 25924 | 0 | 20 | 23 | |
| GSE46452 | MYRIP | 25924 | 2 | 17 | 40 | |
| GSE47630 | MYRIP | 25924 | 2 | 24 | 14 | |
| GSE54993 | MYRIP | 25924 | 7 | 2 | 61 | |
| GSE54994 | MYRIP | 25924 | 0 | 34 | 19 | |
| GSE60625 | MYRIP | 25924 | 5 | 0 | 6 | |
| GSE74703 | MYRIP | 25924 | 0 | 16 | 20 | |
| GSE74704 | MYRIP | 25924 | 0 | 13 | 7 | |
| TCGA | MYRIP | 25924 | 1 | 71 | 24 |
Total number of gains: 17; Total number of losses: 235; Total Number of normals: 236.
Somatic mutations of MYRIP:
Generating mutation plots.
Highly correlated genes for MYRIP:
Showing top 20/1428 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYRIP | CCL14 | 0.837851 | 3 | 0 | 3 |
| MYRIP | PLCXD3 | 0.821801 | 5 | 0 | 5 |
| MYRIP | ABCA8 | 0.817259 | 10 | 0 | 10 |
| MYRIP | ASPA | 0.816051 | 10 | 0 | 10 |
| MYRIP | RSPO1 | 0.808498 | 4 | 0 | 4 |
| MYRIP | XKR4 | 0.793326 | 5 | 0 | 5 |
| MYRIP | STARD9 | 0.786401 | 3 | 0 | 3 |
| MYRIP | C1QTNF7 | 0.785533 | 6 | 0 | 6 |
| MYRIP | ITM2A | 0.784093 | 11 | 0 | 11 |
| MYRIP | CCL23 | 0.783217 | 3 | 0 | 3 |
| MYRIP | RAB9B | 0.781839 | 5 | 0 | 5 |
| MYRIP | CFD | 0.781773 | 9 | 0 | 9 |
| MYRIP | LIFR | 0.776124 | 6 | 0 | 6 |
| MYRIP | F10 | 0.775985 | 9 | 0 | 9 |
| MYRIP | IL34 | 0.774873 | 3 | 0 | 3 |
| MYRIP | CCDC159 | 0.774521 | 3 | 0 | 3 |
| MYRIP | SLC16A4 | 0.765414 | 6 | 0 | 6 |
| MYRIP | PLAC9 | 0.763386 | 5 | 0 | 5 |
| MYRIP | SORCS1 | 0.762056 | 5 | 0 | 5 |
| MYRIP | CLEC3B | 0.759799 | 4 | 0 | 3 |
For details and further investigation, click here
