| Full name: neurofascin | Alias Symbol: NRCAML|KIAA0756|FLJ46866|NF | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 23114 | HGNC ID: HGNC:29866 | Ensembl Gene: ENSG00000163531 | OMIM ID: 609145 |
| Drug and gene relationship at DGIdb | |||
Expression of NFASC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NFASC | 23114 | 213438_at | -1.9756 | 0.0909 | |
| GSE20347 | NFASC | 23114 | 214799_at | -0.1111 | 0.1796 | |
| GSE23400 | NFASC | 23114 | 214799_at | -0.2951 | 0.0000 | |
| GSE26886 | NFASC | 23114 | 230242_at | -0.4360 | 0.0077 | |
| GSE29001 | NFASC | 23114 | 214799_at | 0.0066 | 0.9874 | |
| GSE38129 | NFASC | 23114 | 213438_at | -1.1556 | 0.0096 | |
| GSE45670 | NFASC | 23114 | 230242_at | -0.1842 | 0.1728 | |
| GSE53622 | NFASC | 23114 | 59925 | -1.5353 | 0.0000 | |
| GSE53624 | NFASC | 23114 | 59925 | -1.0356 | 0.0000 | |
| GSE63941 | NFASC | 23114 | 213438_at | -4.8473 | 0.0005 | |
| GSE77861 | NFASC | 23114 | 230242_at | -0.1378 | 0.1593 | |
| GSE97050 | NFASC | 23114 | A_33_P3260342 | -0.4354 | 0.2703 | |
| SRP007169 | NFASC | 23114 | RNAseq | -2.3039 | 0.0003 | |
| SRP008496 | NFASC | 23114 | RNAseq | -1.5473 | 0.0003 | |
| SRP064894 | NFASC | 23114 | RNAseq | -0.6058 | 0.0602 | |
| SRP133303 | NFASC | 23114 | RNAseq | -1.1742 | 0.0024 | |
| SRP159526 | NFASC | 23114 | RNAseq | -0.8363 | 0.0000 | |
| SRP193095 | NFASC | 23114 | RNAseq | -0.1187 | 0.5751 | |
| SRP219564 | NFASC | 23114 | RNAseq | -0.0643 | 0.9265 | |
| TCGA | NFASC | 23114 | RNAseq | -0.3297 | 0.0283 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by NFASC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NFASC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NFASC | 23114 | 11 | 0 | 19 | |
| GSE20123 | NFASC | 23114 | 11 | 0 | 19 | |
| GSE43470 | NFASC | 23114 | 6 | 0 | 37 | |
| GSE46452 | NFASC | 23114 | 3 | 1 | 55 | |
| GSE47630 | NFASC | 23114 | 14 | 0 | 26 | |
| GSE54993 | NFASC | 23114 | 0 | 6 | 64 | |
| GSE54994 | NFASC | 23114 | 15 | 0 | 38 | |
| GSE60625 | NFASC | 23114 | 0 | 0 | 11 | |
| GSE74703 | NFASC | 23114 | 6 | 0 | 30 | |
| GSE74704 | NFASC | 23114 | 5 | 0 | 15 | |
| TCGA | NFASC | 23114 | 43 | 4 | 49 |
Total number of gains: 114; Total number of losses: 11; Total Number of normals: 363.
Somatic mutations of NFASC:
Generating mutation plots.
Highly correlated genes for NFASC:
Showing top 20/1126 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NFASC | MSRB3 | 0.844721 | 4 | 0 | 4 |
| NFASC | AFF3 | 0.833586 | 3 | 0 | 3 |
| NFASC | JAM3 | 0.81661 | 6 | 0 | 6 |
| NFASC | MYOCD | 0.810414 | 5 | 0 | 5 |
| NFASC | LRRN4CL | 0.805292 | 4 | 0 | 4 |
| NFASC | MRVI1 | 0.793816 | 5 | 0 | 5 |
| NFASC | PRICKLE2 | 0.79308 | 4 | 0 | 4 |
| NFASC | MAGI2-AS3 | 0.788355 | 3 | 0 | 3 |
| NFASC | FBXL3 | 0.787196 | 3 | 0 | 3 |
| NFASC | FGL2 | 0.781948 | 6 | 0 | 6 |
| NFASC | FLNC | 0.78081 | 8 | 0 | 8 |
| NFASC | NME5 | 0.774554 | 6 | 0 | 6 |
| NFASC | RCAN2 | 0.774418 | 7 | 0 | 6 |
| NFASC | HSPB2 | 0.76542 | 6 | 0 | 6 |
| NFASC | TCF21 | 0.764186 | 6 | 0 | 6 |
| NFASC | PGM5-AS1 | 0.763063 | 3 | 0 | 3 |
| NFASC | JAM2 | 0.762945 | 6 | 0 | 6 |
| NFASC | PCDH9 | 0.761491 | 6 | 0 | 6 |
| NFASC | SLC2A13 | 0.761383 | 3 | 0 | 3 |
| NFASC | LIMS2 | 0.761054 | 9 | 0 | 9 |
For details and further investigation, click here
