| Full name: protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | Alias Symbol: FLJ10883 | ||
| Type: protein-coding gene | Cytoband: 8q11.23 | ||
| Entrez ID: 115294 | HGNC ID: HGNC:30483 | Ensembl Gene: ENSG00000168300 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PCMTD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PCMTD1 | 115294 | 226119_at | -0.4509 | 0.4976 | |
| GSE26886 | PCMTD1 | 115294 | 226119_at | -0.3744 | 0.1714 | |
| GSE45670 | PCMTD1 | 115294 | 226119_at | -0.6431 | 0.0001 | |
| GSE53622 | PCMTD1 | 115294 | 124506 | -0.7639 | 0.0000 | |
| GSE53624 | PCMTD1 | 115294 | 124506 | -0.6789 | 0.0000 | |
| GSE63941 | PCMTD1 | 115294 | 232382_s_at | 0.9183 | 0.2435 | |
| GSE77861 | PCMTD1 | 115294 | 226119_at | -0.3236 | 0.2309 | |
| GSE97050 | PCMTD1 | 115294 | A_23_P357966 | -0.8345 | 0.1153 | |
| SRP007169 | PCMTD1 | 115294 | RNAseq | -1.5366 | 0.0000 | |
| SRP008496 | PCMTD1 | 115294 | RNAseq | -0.9026 | 0.0086 | |
| SRP064894 | PCMTD1 | 115294 | RNAseq | -0.1610 | 0.4497 | |
| SRP133303 | PCMTD1 | 115294 | RNAseq | -0.3403 | 0.0353 | |
| SRP159526 | PCMTD1 | 115294 | RNAseq | -0.1111 | 0.7669 | |
| SRP193095 | PCMTD1 | 115294 | RNAseq | -0.3120 | 0.0568 | |
| SRP219564 | PCMTD1 | 115294 | RNAseq | -0.4760 | 0.1891 | |
| TCGA | PCMTD1 | 115294 | RNAseq | -0.2199 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PCMTD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PCMTD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PCMTD1 | 115294 | 15 | 2 | 13 | |
| GSE20123 | PCMTD1 | 115294 | 15 | 2 | 13 | |
| GSE43470 | PCMTD1 | 115294 | 14 | 3 | 26 | |
| GSE46452 | PCMTD1 | 115294 | 21 | 3 | 35 | |
| GSE47630 | PCMTD1 | 115294 | 23 | 1 | 16 | |
| GSE54993 | PCMTD1 | 115294 | 1 | 16 | 53 | |
| GSE54994 | PCMTD1 | 115294 | 28 | 0 | 25 | |
| GSE60625 | PCMTD1 | 115294 | 0 | 4 | 7 | |
| GSE74703 | PCMTD1 | 115294 | 13 | 2 | 21 | |
| GSE74704 | PCMTD1 | 115294 | 11 | 0 | 9 | |
| TCGA | PCMTD1 | 115294 | 43 | 9 | 44 |
Total number of gains: 184; Total number of losses: 42; Total Number of normals: 262.
Somatic mutations of PCMTD1:
Generating mutation plots.
Highly correlated genes for PCMTD1:
Showing top 20/718 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PCMTD1 | FOXO3 | 0.780631 | 4 | 0 | 4 |
| PCMTD1 | MLLT3 | 0.776566 | 3 | 0 | 3 |
| PCMTD1 | PLEKHB1 | 0.764852 | 3 | 0 | 3 |
| PCMTD1 | ZNF664 | 0.760368 | 3 | 0 | 3 |
| PCMTD1 | CCDC110 | 0.745115 | 3 | 0 | 3 |
| PCMTD1 | PDCD4 | 0.740499 | 3 | 0 | 3 |
| PCMTD1 | IRAK1BP1 | 0.740066 | 3 | 0 | 3 |
| PCMTD1 | XPC | 0.730225 | 3 | 0 | 3 |
| PCMTD1 | PLCL1 | 0.729644 | 4 | 0 | 4 |
| PCMTD1 | FBXO9 | 0.72546 | 5 | 0 | 5 |
| PCMTD1 | AZIN1 | 0.724795 | 3 | 0 | 3 |
| PCMTD1 | DIS3L | 0.718718 | 3 | 0 | 3 |
| PCMTD1 | NPY1R | 0.716986 | 3 | 0 | 3 |
| PCMTD1 | CWC27 | 0.711365 | 3 | 0 | 3 |
| PCMTD1 | FAM104B | 0.710595 | 3 | 0 | 3 |
| PCMTD1 | SOCS5 | 0.709853 | 3 | 0 | 3 |
| PCMTD1 | EZH1 | 0.707942 | 6 | 0 | 6 |
| PCMTD1 | DZIP3 | 0.707679 | 3 | 0 | 3 |
| PCMTD1 | FDX1 | 0.705946 | 3 | 0 | 3 |
| PCMTD1 | EPM2AIP1 | 0.705649 | 6 | 0 | 6 |
For details and further investigation, click here
