| Full name: kelch repeat and BTB domain containing 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q22.3 | ||
| Entrez ID: 143879 | HGNC ID: HGNC:22934 | Ensembl Gene: ENSG00000182359 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KBTBD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KBTBD3 | 143879 | 228777_at | -0.1336 | 0.6401 | |
| GSE26886 | KBTBD3 | 143879 | 228777_at | 0.0536 | 0.7762 | |
| GSE45670 | KBTBD3 | 143879 | 228777_at | -0.2110 | 0.3930 | |
| GSE53622 | KBTBD3 | 143879 | 96272 | -1.4478 | 0.0000 | |
| GSE53624 | KBTBD3 | 143879 | 96272 | -1.1828 | 0.0000 | |
| GSE63941 | KBTBD3 | 143879 | 228777_at | 0.1356 | 0.8322 | |
| GSE77861 | KBTBD3 | 143879 | 228777_at | -0.1441 | 0.3835 | |
| GSE97050 | KBTBD3 | 143879 | A_23_P127557 | -0.1221 | 0.5506 | |
| SRP007169 | KBTBD3 | 143879 | RNAseq | -0.9241 | 0.0847 | |
| SRP008496 | KBTBD3 | 143879 | RNAseq | -0.8947 | 0.0221 | |
| SRP064894 | KBTBD3 | 143879 | RNAseq | -0.7308 | 0.0026 | |
| SRP133303 | KBTBD3 | 143879 | RNAseq | -0.8633 | 0.0010 | |
| SRP159526 | KBTBD3 | 143879 | RNAseq | -0.6746 | 0.0584 | |
| SRP193095 | KBTBD3 | 143879 | RNAseq | -1.2979 | 0.0000 | |
| SRP219564 | KBTBD3 | 143879 | RNAseq | -0.6558 | 0.1226 | |
| TCGA | KBTBD3 | 143879 | RNAseq | -0.5015 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by KBTBD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KBTBD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KBTBD3 | 143879 | 0 | 13 | 17 | |
| GSE20123 | KBTBD3 | 143879 | 0 | 13 | 17 | |
| GSE43470 | KBTBD3 | 143879 | 2 | 6 | 35 | |
| GSE46452 | KBTBD3 | 143879 | 3 | 26 | 30 | |
| GSE47630 | KBTBD3 | 143879 | 2 | 19 | 19 | |
| GSE54993 | KBTBD3 | 143879 | 10 | 0 | 60 | |
| GSE54994 | KBTBD3 | 143879 | 4 | 19 | 30 | |
| GSE60625 | KBTBD3 | 143879 | 0 | 3 | 8 | |
| GSE74703 | KBTBD3 | 143879 | 1 | 4 | 31 | |
| GSE74704 | KBTBD3 | 143879 | 0 | 9 | 11 | |
| TCGA | KBTBD3 | 143879 | 7 | 48 | 41 |
Total number of gains: 29; Total number of losses: 160; Total Number of normals: 299.
Somatic mutations of KBTBD3:
Generating mutation plots.
Highly correlated genes for KBTBD3:
Showing top 20/730 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KBTBD3 | ZCWPW2 | 0.804954 | 3 | 0 | 3 |
| KBTBD3 | CX3CR1 | 0.742255 | 3 | 0 | 3 |
| KBTBD3 | GNA14 | 0.739458 | 3 | 0 | 3 |
| KBTBD3 | BTD | 0.738826 | 4 | 0 | 4 |
| KBTBD3 | AGO4 | 0.736685 | 3 | 0 | 3 |
| KBTBD3 | GPRASP2 | 0.73242 | 3 | 0 | 3 |
| KBTBD3 | RGN | 0.729704 | 3 | 0 | 3 |
| KBTBD3 | PKIA | 0.729117 | 3 | 0 | 3 |
| KBTBD3 | KCTD6 | 0.724764 | 3 | 0 | 3 |
| KBTBD3 | ROR1 | 0.723777 | 3 | 0 | 3 |
| KBTBD3 | FBXL17 | 0.719959 | 3 | 0 | 3 |
| KBTBD3 | SLC4A4 | 0.71764 | 4 | 0 | 4 |
| KBTBD3 | ZNF619 | 0.717528 | 3 | 0 | 3 |
| KBTBD3 | USO1 | 0.716146 | 3 | 0 | 3 |
| KBTBD3 | HADHA | 0.714055 | 3 | 0 | 3 |
| KBTBD3 | SLAIN1 | 0.709936 | 3 | 0 | 3 |
| KBTBD3 | NR2F1 | 0.707909 | 3 | 0 | 3 |
| KBTBD3 | ANO5 | 0.704475 | 4 | 0 | 4 |
| KBTBD3 | ZFP3 | 0.699693 | 3 | 0 | 3 |
| KBTBD3 | FIG4 | 0.699661 | 3 | 0 | 3 |
For details and further investigation, click here
