| Full name: 1-acylglycerol-3-phosphate O-acyltransferase 2 | Alias Symbol: LPAAT-beta | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 10555 | HGNC ID: HGNC:325 | Ensembl Gene: ENSG00000169692 | OMIM ID: 603100 |
| Drug and gene relationship at DGIdb | |||
Expression of AGPAT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AGPAT2 | 10555 | 32837_at | -0.2778 | 0.3765 | |
| GSE20347 | AGPAT2 | 10555 | 32837_at | -0.4755 | 0.0000 | |
| GSE23400 | AGPAT2 | 10555 | 32837_at | -0.2031 | 0.0007 | |
| GSE26886 | AGPAT2 | 10555 | 32837_at | -0.4677 | 0.0119 | |
| GSE29001 | AGPAT2 | 10555 | 32837_at | -0.3890 | 0.0050 | |
| GSE38129 | AGPAT2 | 10555 | 32837_at | -0.2407 | 0.0389 | |
| GSE45670 | AGPAT2 | 10555 | 32837_at | 0.0297 | 0.8361 | |
| GSE53622 | AGPAT2 | 10555 | 67021 | -0.4467 | 0.0000 | |
| GSE53624 | AGPAT2 | 10555 | 67021 | -0.4342 | 0.0000 | |
| GSE63941 | AGPAT2 | 10555 | 32837_at | 1.2086 | 0.0027 | |
| GSE77861 | AGPAT2 | 10555 | 32837_at | -0.0308 | 0.8694 | |
| GSE97050 | AGPAT2 | 10555 | A_33_P3360540 | -0.1685 | 0.6253 | |
| SRP007169 | AGPAT2 | 10555 | RNAseq | -1.4171 | 0.0001 | |
| SRP008496 | AGPAT2 | 10555 | RNAseq | -1.6124 | 0.0000 | |
| SRP064894 | AGPAT2 | 10555 | RNAseq | 0.5913 | 0.1509 | |
| SRP133303 | AGPAT2 | 10555 | RNAseq | -0.0360 | 0.8574 | |
| SRP159526 | AGPAT2 | 10555 | RNAseq | -0.3368 | 0.0551 | |
| SRP193095 | AGPAT2 | 10555 | RNAseq | -0.5964 | 0.0064 | |
| SRP219564 | AGPAT2 | 10555 | RNAseq | -0.1793 | 0.6874 | |
| TCGA | AGPAT2 | 10555 | RNAseq | 0.0833 | 0.3132 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by AGPAT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AGPAT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AGPAT2 | 10555 | 4 | 7 | 19 | |
| GSE20123 | AGPAT2 | 10555 | 4 | 7 | 19 | |
| GSE43470 | AGPAT2 | 10555 | 3 | 7 | 33 | |
| GSE46452 | AGPAT2 | 10555 | 6 | 13 | 40 | |
| GSE47630 | AGPAT2 | 10555 | 6 | 15 | 19 | |
| GSE54993 | AGPAT2 | 10555 | 3 | 3 | 64 | |
| GSE54994 | AGPAT2 | 10555 | 12 | 8 | 33 | |
| GSE60625 | AGPAT2 | 10555 | 0 | 0 | 11 | |
| GSE74703 | AGPAT2 | 10555 | 3 | 5 | 28 | |
| GSE74704 | AGPAT2 | 10555 | 2 | 5 | 13 | |
| TCGA | AGPAT2 | 10555 | 28 | 23 | 45 |
Total number of gains: 71; Total number of losses: 93; Total Number of normals: 324.
Somatic mutations of AGPAT2:
Generating mutation plots.
Highly correlated genes for AGPAT2:
Showing top 20/580 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AGPAT2 | LRSAM1 | 0.783219 | 3 | 0 | 3 |
| AGPAT2 | RNF32 | 0.772797 | 3 | 0 | 3 |
| AGPAT2 | FBF1 | 0.722984 | 3 | 0 | 3 |
| AGPAT2 | ARHGAP30 | 0.710322 | 4 | 0 | 3 |
| AGPAT2 | KCNT1 | 0.708724 | 4 | 0 | 3 |
| AGPAT2 | FAM171A2 | 0.698855 | 4 | 0 | 3 |
| AGPAT2 | MPDU1 | 0.693471 | 3 | 0 | 3 |
| AGPAT2 | CLEC18C | 0.692451 | 3 | 0 | 3 |
| AGPAT2 | SP8 | 0.686165 | 3 | 0 | 3 |
| AGPAT2 | MFSD2B | 0.684829 | 3 | 0 | 3 |
| AGPAT2 | SLC25A47 | 0.683249 | 4 | 0 | 3 |
| AGPAT2 | MAT1A | 0.677919 | 4 | 0 | 3 |
| AGPAT2 | TTLL9 | 0.673733 | 4 | 0 | 3 |
| AGPAT2 | FAM163B | 0.670071 | 3 | 0 | 3 |
| AGPAT2 | DNAH6 | 0.667458 | 6 | 0 | 5 |
| AGPAT2 | MBD6 | 0.667311 | 3 | 0 | 3 |
| AGPAT2 | ADAMTS13 | 0.665026 | 3 | 0 | 3 |
| AGPAT2 | ABHD11 | 0.66335 | 3 | 0 | 3 |
| AGPAT2 | TPRN | 0.660904 | 6 | 0 | 5 |
| AGPAT2 | SLC25A5-AS1 | 0.659628 | 3 | 0 | 3 |
For details and further investigation, click here
