| Full name: angiotensin II receptor type 2 | Alias Symbol: AT2|MRX88 | ||
| Type: protein-coding gene | Cytoband: Xq23 | ||
| Entrez ID: 186 | HGNC ID: HGNC:338 | Ensembl Gene: ENSG00000180772 | OMIM ID: 300034 |
| Drug and gene relationship at DGIdb | |||
AGTR2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04261 | Adrenergic signaling in cardiomyocytes |
Expression of AGTR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AGTR2 | 186 | 222321_at | -0.0767 | 0.7041 | |
| GSE20347 | AGTR2 | 186 | 222321_at | 0.0052 | 0.9412 | |
| GSE23400 | AGTR2 | 186 | 222321_at | -0.0412 | 0.2886 | |
| GSE26886 | AGTR2 | 186 | 222321_at | 0.1027 | 0.2810 | |
| GSE29001 | AGTR2 | 186 | 207293_s_at | -0.0163 | 0.9207 | |
| GSE38129 | AGTR2 | 186 | 222321_at | -0.0981 | 0.1444 | |
| GSE45670 | AGTR2 | 186 | 222321_at | 0.0471 | 0.6541 | |
| GSE53622 | AGTR2 | 186 | 101919 | -0.3813 | 0.0004 | |
| GSE53624 | AGTR2 | 186 | 101919 | -0.2955 | 0.0040 | |
| GSE63941 | AGTR2 | 186 | 222321_at | 0.3905 | 0.0057 | |
| GSE77861 | AGTR2 | 186 | 222321_at | -0.0546 | 0.5527 | |
| TCGA | AGTR2 | 186 | RNAseq | -1.5746 | 0.2452 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AGTR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AGTR2:
No record found for this gene.
Somatic mutations of AGTR2:
Generating mutation plots.
Highly correlated genes for AGTR2:
Showing top 20/789 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AGTR2 | SERPIND1 | 0.767526 | 3 | 0 | 3 |
| AGTR2 | RFPL2 | 0.72416 | 3 | 0 | 3 |
| AGTR2 | NPY | 0.705194 | 3 | 0 | 3 |
| AGTR2 | FGF4 | 0.700384 | 4 | 0 | 3 |
| AGTR2 | IL9R | 0.697947 | 3 | 0 | 3 |
| AGTR2 | TUBA8 | 0.693525 | 4 | 0 | 4 |
| AGTR2 | GUCY2D | 0.692516 | 3 | 0 | 3 |
| AGTR2 | AMELY | 0.691807 | 5 | 0 | 4 |
| AGTR2 | KRT38 | 0.689609 | 3 | 0 | 3 |
| AGTR2 | GALR1 | 0.68795 | 4 | 0 | 3 |
| AGTR2 | MASP2 | 0.685356 | 4 | 0 | 4 |
| AGTR2 | KIR2DL5A | 0.678973 | 4 | 0 | 4 |
| AGTR2 | MSH4 | 0.677613 | 4 | 0 | 3 |
| AGTR2 | CACNG3 | 0.675047 | 5 | 0 | 5 |
| AGTR2 | PRAMEF10 | 0.673708 | 4 | 0 | 3 |
| AGTR2 | S100G | 0.672751 | 3 | 0 | 3 |
| AGTR2 | GIP | 0.661435 | 6 | 0 | 6 |
| AGTR2 | SCGB1D1 | 0.660173 | 3 | 0 | 3 |
| AGTR2 | C8B | 0.655678 | 5 | 0 | 4 |
| AGTR2 | CRP | 0.653749 | 4 | 0 | 3 |
For details and further investigation, click here
