| Full name: complement C8 beta chain | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p32.2 | ||
| Entrez ID: 732 | HGNC ID: HGNC:1353 | Ensembl Gene: ENSG00000021852 | OMIM ID: 120960 |
| Drug and gene relationship at DGIdb | |||
Expression of C8B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C8B | 732 | 206979_at | -0.1458 | 0.6391 | |
| GSE20347 | C8B | 732 | 206979_at | -0.0903 | 0.4276 | |
| GSE23400 | C8B | 732 | 206979_at | -0.1682 | 0.0000 | |
| GSE26886 | C8B | 732 | 206979_at | -0.1112 | 0.4065 | |
| GSE29001 | C8B | 732 | 206979_at | -0.2722 | 0.0787 | |
| GSE38129 | C8B | 732 | 206979_at | -0.2200 | 0.0151 | |
| GSE45670 | C8B | 732 | 206979_at | 0.0797 | 0.5509 | |
| GSE53622 | C8B | 732 | 90938 | 0.0854 | 0.5379 | |
| GSE53624 | C8B | 732 | 90938 | 0.2079 | 0.0907 | |
| GSE63941 | C8B | 732 | 206979_at | -0.0345 | 0.8601 | |
| GSE77861 | C8B | 732 | 206979_at | -0.1308 | 0.2091 | |
| TCGA | C8B | 732 | RNAseq | 1.6059 | 0.3903 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C8B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C8B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C8B | 732 | 3 | 5 | 22 | |
| GSE20123 | C8B | 732 | 3 | 4 | 23 | |
| GSE43470 | C8B | 732 | 6 | 1 | 36 | |
| GSE46452 | C8B | 732 | 2 | 1 | 56 | |
| GSE47630 | C8B | 732 | 8 | 4 | 28 | |
| GSE54993 | C8B | 732 | 0 | 0 | 70 | |
| GSE54994 | C8B | 732 | 9 | 2 | 42 | |
| GSE60625 | C8B | 732 | 0 | 0 | 11 | |
| GSE74703 | C8B | 732 | 5 | 1 | 30 | |
| GSE74704 | C8B | 732 | 2 | 0 | 18 | |
| TCGA | C8B | 732 | 10 | 18 | 68 |
Total number of gains: 48; Total number of losses: 36; Total Number of normals: 404.
Somatic mutations of C8B:
Generating mutation plots.
Highly correlated genes for C8B:
Showing top 20/813 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C8B | SCGB1D1 | 0.743416 | 3 | 0 | 3 |
| C8B | FOXP3 | 0.70846 | 3 | 0 | 3 |
| C8B | PTPRN2 | 0.705406 | 4 | 0 | 3 |
| C8B | P2RX6 | 0.696997 | 4 | 0 | 4 |
| C8B | SPX | 0.686773 | 5 | 0 | 5 |
| C8B | KRTAP13-1 | 0.685644 | 3 | 0 | 3 |
| C8B | MAML3 | 0.685161 | 3 | 0 | 3 |
| C8B | SENCR | 0.676867 | 3 | 0 | 3 |
| C8B | HEYL | 0.676377 | 4 | 0 | 4 |
| C8B | ART1 | 0.669873 | 6 | 0 | 5 |
| C8B | SSTR4 | 0.667472 | 6 | 0 | 5 |
| C8B | AOC2 | 0.667226 | 3 | 0 | 3 |
| C8B | C5AR2 | 0.66454 | 5 | 0 | 4 |
| C8B | GIP | 0.663267 | 4 | 0 | 3 |
| C8B | GRPR | 0.660222 | 6 | 0 | 5 |
| C8B | KCNC4 | 0.657572 | 4 | 0 | 3 |
| C8B | GRIK3 | 0.65742 | 4 | 0 | 4 |
| C8B | AGTR2 | 0.655678 | 5 | 0 | 4 |
| C8B | CHST4 | 0.654266 | 6 | 0 | 5 |
| C8B | GRM2 | 0.653252 | 4 | 0 | 3 |
For details and further investigation, click here
