| Full name: tubulin alpha 8 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q11.21 | ||
| Entrez ID: 51807 | HGNC ID: HGNC:12410 | Ensembl Gene: ENSG00000183785 | OMIM ID: 605742 |
| Drug and gene relationship at DGIdb | |||
TUBA8 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04210 | Apoptosis | |
| hsa05130 | Pathogenic Escherichia coli infection |
Expression of TUBA8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TUBA8 | 51807 | 220069_at | -0.1825 | 0.4604 | |
| GSE20347 | TUBA8 | 51807 | 220069_at | -0.0829 | 0.2449 | |
| GSE23400 | TUBA8 | 51807 | 220069_at | -0.1133 | 0.0158 | |
| GSE26886 | TUBA8 | 51807 | 220069_at | -0.1143 | 0.4001 | |
| GSE29001 | TUBA8 | 51807 | 220069_at | -0.1463 | 0.2981 | |
| GSE38129 | TUBA8 | 51807 | 220069_at | -0.2225 | 0.0392 | |
| GSE45670 | TUBA8 | 51807 | 220069_at | -0.0254 | 0.7983 | |
| GSE63941 | TUBA8 | 51807 | 220069_at | 0.0711 | 0.6724 | |
| GSE77861 | TUBA8 | 51807 | 220069_at | -0.1465 | 0.2414 | |
| GSE97050 | TUBA8 | 51807 | A_24_P160104 | -0.1185 | 0.6951 | |
| SRP064894 | TUBA8 | 51807 | RNAseq | 0.7292 | 0.0487 | |
| SRP133303 | TUBA8 | 51807 | RNAseq | 0.2106 | 0.5502 | |
| SRP159526 | TUBA8 | 51807 | RNAseq | 0.6646 | 0.1488 | |
| SRP219564 | TUBA8 | 51807 | RNAseq | 0.9154 | 0.2225 | |
| TCGA | TUBA8 | 51807 | RNAseq | -0.6124 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TUBA8 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TUBA8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TUBA8 | 51807 | 4 | 7 | 19 | |
| GSE20123 | TUBA8 | 51807 | 4 | 7 | 19 | |
| GSE43470 | TUBA8 | 51807 | 5 | 7 | 31 | |
| GSE46452 | TUBA8 | 51807 | 32 | 2 | 25 | |
| GSE47630 | TUBA8 | 51807 | 8 | 5 | 27 | |
| GSE54993 | TUBA8 | 51807 | 3 | 6 | 61 | |
| GSE54994 | TUBA8 | 51807 | 12 | 7 | 34 | |
| GSE60625 | TUBA8 | 51807 | 5 | 0 | 6 | |
| GSE74703 | TUBA8 | 51807 | 5 | 5 | 26 | |
| GSE74704 | TUBA8 | 51807 | 2 | 4 | 14 | |
| TCGA | TUBA8 | 51807 | 29 | 17 | 50 |
Total number of gains: 109; Total number of losses: 67; Total Number of normals: 312.
Somatic mutations of TUBA8:
Generating mutation plots.
Highly correlated genes for TUBA8:
Showing top 20/758 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TUBA8 | OR4D2 | 0.785448 | 3 | 0 | 3 |
| TUBA8 | IQCF3 | 0.775289 | 3 | 0 | 3 |
| TUBA8 | CDH2 | 0.766418 | 3 | 0 | 3 |
| TUBA8 | OR4D1 | 0.762424 | 3 | 0 | 3 |
| TUBA8 | OPN4 | 0.762124 | 3 | 0 | 3 |
| TUBA8 | C20orf173 | 0.758796 | 4 | 0 | 3 |
| TUBA8 | BPIFB4 | 0.728194 | 3 | 0 | 3 |
| TUBA8 | GSTM5 | 0.727876 | 4 | 0 | 4 |
| TUBA8 | ZNF491 | 0.724378 | 3 | 0 | 3 |
| TUBA8 | CPNE6 | 0.714449 | 4 | 0 | 3 |
| TUBA8 | KRTAP9-9 | 0.709879 | 3 | 0 | 3 |
| TUBA8 | FAM71F1 | 0.709843 | 4 | 0 | 4 |
| TUBA8 | RNF151 | 0.70119 | 4 | 0 | 4 |
| TUBA8 | ARVCF | 0.700435 | 5 | 0 | 5 |
| TUBA8 | MUC13 | 0.695316 | 3 | 0 | 3 |
| TUBA8 | CDC42EP2 | 0.695252 | 3 | 0 | 3 |
| TUBA8 | AGTR2 | 0.693525 | 4 | 0 | 4 |
| TUBA8 | C11orf16 | 0.691967 | 6 | 0 | 5 |
| TUBA8 | LTC4S | 0.689894 | 3 | 0 | 3 |
| TUBA8 | OR2H2 | 0.688967 | 8 | 0 | 7 |
For details and further investigation, click here
