| Full name: calcium voltage-gated channel auxiliary subunit gamma 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16p12.1 | ||
| Entrez ID: 10368 | HGNC ID: HGNC:1407 | Ensembl Gene: ENSG00000006116 | OMIM ID: 606403 |
| Drug and gene relationship at DGIdb | |||
CACNG3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04010 | MAPK signaling pathway | |
| hsa04261 | Adrenergic signaling in cardiomyocytes | |
| hsa04921 | Oxytocin signaling pathway |
Expression of CACNG3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CACNG3 | 10368 | 206384_at | -0.0318 | 0.8977 | |
| GSE20347 | CACNG3 | 10368 | 206384_at | -0.0552 | 0.4825 | |
| GSE23400 | CACNG3 | 10368 | 206384_at | -0.1893 | 0.0000 | |
| GSE26886 | CACNG3 | 10368 | 206384_at | 0.0578 | 0.7000 | |
| GSE29001 | CACNG3 | 10368 | 206384_at | -0.0965 | 0.6667 | |
| GSE38129 | CACNG3 | 10368 | 206384_at | -0.1260 | 0.2636 | |
| GSE45670 | CACNG3 | 10368 | 206384_at | 0.0049 | 0.9566 | |
| GSE53622 | CACNG3 | 10368 | 95424 | 0.1905 | 0.0795 | |
| GSE53624 | CACNG3 | 10368 | 95424 | -0.2320 | 0.0416 | |
| GSE63941 | CACNG3 | 10368 | 206384_at | 0.4010 | 0.0052 | |
| GSE77861 | CACNG3 | 10368 | 206384_at | -0.1363 | 0.2952 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CACNG3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CACNG3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CACNG3 | 10368 | 4 | 4 | 22 | |
| GSE20123 | CACNG3 | 10368 | 4 | 3 | 23 | |
| GSE43470 | CACNG3 | 10368 | 4 | 3 | 36 | |
| GSE46452 | CACNG3 | 10368 | 38 | 1 | 20 | |
| GSE47630 | CACNG3 | 10368 | 11 | 6 | 23 | |
| GSE54993 | CACNG3 | 10368 | 3 | 5 | 62 | |
| GSE54994 | CACNG3 | 10368 | 4 | 9 | 40 | |
| GSE60625 | CACNG3 | 10368 | 4 | 0 | 7 | |
| GSE74703 | CACNG3 | 10368 | 4 | 2 | 30 | |
| GSE74704 | CACNG3 | 10368 | 2 | 1 | 17 | |
| TCGA | CACNG3 | 10368 | 19 | 13 | 64 |
Total number of gains: 97; Total number of losses: 47; Total Number of normals: 344.
Somatic mutations of CACNG3:
Generating mutation plots.
Highly correlated genes for CACNG3:
Showing top 20/988 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CACNG3 | MEFV | 0.695498 | 4 | 0 | 4 |
| CACNG3 | UMOD | 0.683088 | 5 | 0 | 5 |
| CACNG3 | ECE2 | 0.680959 | 5 | 0 | 5 |
| CACNG3 | OR3A3 | 0.679215 | 4 | 0 | 4 |
| CACNG3 | CRP | 0.679193 | 6 | 0 | 6 |
| CACNG3 | SLC17A3 | 0.675542 | 4 | 0 | 4 |
| CACNG3 | ZNF460 | 0.675206 | 4 | 0 | 4 |
| CACNG3 | AGTR2 | 0.675047 | 5 | 0 | 5 |
| CACNG3 | GNRH2 | 0.672741 | 4 | 0 | 4 |
| CACNG3 | ZMAT4 | 0.672153 | 4 | 0 | 3 |
| CACNG3 | SLC22A13 | 0.668959 | 5 | 0 | 5 |
| CACNG3 | LGR5 | 0.666329 | 3 | 0 | 3 |
| CACNG3 | CCIN | 0.664453 | 5 | 0 | 4 |
| CACNG3 | SIX6 | 0.662309 | 5 | 0 | 4 |
| CACNG3 | ARSE | 0.661631 | 3 | 0 | 3 |
| CACNG3 | ATG10 | 0.661186 | 4 | 0 | 4 |
| CACNG3 | TEX13A | 0.660324 | 4 | 0 | 4 |
| CACNG3 | AQP8 | 0.659311 | 4 | 0 | 4 |
| CACNG3 | NPFFR1 | 0.658347 | 5 | 0 | 4 |
| CACNG3 | HABP2 | 0.657136 | 4 | 0 | 4 |
For details and further investigation, click here
