| Full name: allograft inflammatory factor 1 like | Alias Symbol: IBA2|FLJ12783 | ||
| Type: protein-coding gene | Cytoband: 9q34.12-q34.13 | ||
| Entrez ID: 83543 | HGNC ID: HGNC:28904 | Ensembl Gene: ENSG00000126878 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of AIF1L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AIF1L | 83543 | 223075_s_at | -1.2663 | 0.2874 | |
| GSE26886 | AIF1L | 83543 | 223075_s_at | -4.0558 | 0.0000 | |
| GSE45670 | AIF1L | 83543 | 223075_s_at | -1.5997 | 0.0132 | |
| GSE53622 | AIF1L | 83543 | 82586 | -2.1390 | 0.0000 | |
| GSE53624 | AIF1L | 83543 | 82586 | -2.3142 | 0.0000 | |
| GSE63941 | AIF1L | 83543 | 223075_s_at | 3.0982 | 0.0001 | |
| GSE77861 | AIF1L | 83543 | 223075_s_at | -2.9096 | 0.0004 | |
| GSE97050 | AIF1L | 83543 | A_33_P3260026 | -1.3561 | 0.1998 | |
| SRP007169 | AIF1L | 83543 | RNAseq | -5.2850 | 0.0000 | |
| SRP008496 | AIF1L | 83543 | RNAseq | -5.3816 | 0.0000 | |
| SRP064894 | AIF1L | 83543 | RNAseq | -4.4089 | 0.0000 | |
| SRP133303 | AIF1L | 83543 | RNAseq | -4.5795 | 0.0000 | |
| SRP159526 | AIF1L | 83543 | RNAseq | -3.4574 | 0.0000 | |
| SRP193095 | AIF1L | 83543 | RNAseq | -4.0285 | 0.0000 | |
| SRP219564 | AIF1L | 83543 | RNAseq | -3.9108 | 0.0000 | |
| TCGA | AIF1L | 83543 | RNAseq | -0.3094 | 0.0416 |
Upregulated datasets: 1; Downregulated datasets: 12.
Survival by AIF1L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AIF1L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AIF1L | 83543 | 6 | 9 | 15 | |
| GSE20123 | AIF1L | 83543 | 6 | 9 | 15 | |
| GSE43470 | AIF1L | 83543 | 5 | 7 | 31 | |
| GSE46452 | AIF1L | 83543 | 6 | 13 | 40 | |
| GSE47630 | AIF1L | 83543 | 3 | 16 | 21 | |
| GSE54993 | AIF1L | 83543 | 3 | 3 | 64 | |
| GSE54994 | AIF1L | 83543 | 12 | 9 | 32 | |
| GSE60625 | AIF1L | 83543 | 0 | 0 | 11 | |
| GSE74703 | AIF1L | 83543 | 5 | 5 | 26 | |
| GSE74704 | AIF1L | 83543 | 3 | 7 | 10 | |
| TCGA | AIF1L | 83543 | 27 | 26 | 43 |
Total number of gains: 76; Total number of losses: 104; Total Number of normals: 308.
Somatic mutations of AIF1L:
Generating mutation plots.
Highly correlated genes for AIF1L:
Showing top 20/1121 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AIF1L | GYS2 | 0.872545 | 6 | 0 | 6 |
| AIF1L | NCCRP1 | 0.870146 | 3 | 0 | 3 |
| AIF1L | MORN3 | 0.868227 | 4 | 0 | 4 |
| AIF1L | VSIG10L | 0.867059 | 7 | 0 | 7 |
| AIF1L | CYSRT1 | 0.863656 | 6 | 0 | 6 |
| AIF1L | SFTA2 | 0.860481 | 4 | 0 | 4 |
| AIF1L | UPK1A | 0.848884 | 7 | 0 | 7 |
| AIF1L | PADI1 | 0.843212 | 5 | 0 | 5 |
| AIF1L | PSCA | 0.841593 | 4 | 0 | 4 |
| AIF1L | MFSD2B | 0.840797 | 3 | 0 | 3 |
| AIF1L | UBL3 | 0.839249 | 7 | 0 | 7 |
| AIF1L | RAET1E | 0.83764 | 7 | 0 | 7 |
| AIF1L | EPS8L2 | 0.837585 | 7 | 0 | 7 |
| AIF1L | FLG | 0.836456 | 7 | 0 | 7 |
| AIF1L | ARHGAP27 | 0.834708 | 7 | 0 | 7 |
| AIF1L | C1orf116 | 0.833949 | 8 | 0 | 8 |
| AIF1L | FAM163B | 0.833151 | 3 | 0 | 3 |
| AIF1L | GDPD3 | 0.832705 | 7 | 0 | 7 |
| AIF1L | MAL | 0.832175 | 7 | 0 | 7 |
| AIF1L | KRTAP20-1 | 0.830461 | 3 | 0 | 3 |
For details and further investigation, click here
