| Full name: Rho GTPase activating protein 27 | Alias Symbol: CAMGAP1|FLJ43547|SH3P20 | ||
| Type: protein-coding gene | Cytoband: 17q21.31 | ||
| Entrez ID: 201176 | HGNC ID: HGNC:31813 | Ensembl Gene: ENSG00000159314 | OMIM ID: 610591 |
| Drug and gene relationship at DGIdb | |||
Expression of ARHGAP27:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARHGAP27 | 201176 | 225618_at | -0.9128 | 0.3398 | |
| GSE26886 | ARHGAP27 | 201176 | 225618_at | -2.2448 | 0.0000 | |
| GSE45670 | ARHGAP27 | 201176 | 225618_at | -1.0738 | 0.0021 | |
| GSE53622 | ARHGAP27 | 201176 | 90968 | -1.5372 | 0.0000 | |
| GSE53624 | ARHGAP27 | 201176 | 90968 | -1.8668 | 0.0000 | |
| GSE63941 | ARHGAP27 | 201176 | 225618_at | 1.2499 | 0.0016 | |
| GSE77861 | ARHGAP27 | 201176 | 225618_at | -1.0007 | 0.0197 | |
| GSE97050 | ARHGAP27 | 201176 | A_33_P3228558 | -0.3312 | 0.7043 | |
| SRP007169 | ARHGAP27 | 201176 | RNAseq | -2.5846 | 0.0000 | |
| SRP008496 | ARHGAP27 | 201176 | RNAseq | -2.9164 | 0.0000 | |
| SRP064894 | ARHGAP27 | 201176 | RNAseq | -2.1213 | 0.0000 | |
| SRP133303 | ARHGAP27 | 201176 | RNAseq | -1.9169 | 0.0000 | |
| SRP159526 | ARHGAP27 | 201176 | RNAseq | -2.3404 | 0.0000 | |
| SRP193095 | ARHGAP27 | 201176 | RNAseq | -1.9183 | 0.0000 | |
| SRP219564 | ARHGAP27 | 201176 | RNAseq | -2.1494 | 0.0048 | |
| TCGA | ARHGAP27 | 201176 | RNAseq | 0.0844 | 0.3388 |
Upregulated datasets: 1; Downregulated datasets: 12.
Survival by ARHGAP27 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARHGAP27:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARHGAP27 | 201176 | 6 | 2 | 22 | |
| GSE20123 | ARHGAP27 | 201176 | 6 | 2 | 22 | |
| GSE43470 | ARHGAP27 | 201176 | 1 | 2 | 40 | |
| GSE46452 | ARHGAP27 | 201176 | 32 | 0 | 27 | |
| GSE47630 | ARHGAP27 | 201176 | 9 | 0 | 31 | |
| GSE54993 | ARHGAP27 | 201176 | 3 | 4 | 63 | |
| GSE54994 | ARHGAP27 | 201176 | 9 | 5 | 39 | |
| GSE60625 | ARHGAP27 | 201176 | 4 | 0 | 7 | |
| GSE74703 | ARHGAP27 | 201176 | 1 | 1 | 34 | |
| GSE74704 | ARHGAP27 | 201176 | 4 | 1 | 15 | |
| TCGA | ARHGAP27 | 201176 | 26 | 7 | 63 |
Total number of gains: 101; Total number of losses: 24; Total Number of normals: 363.
Somatic mutations of ARHGAP27:
Generating mutation plots.
Highly correlated genes for ARHGAP27:
Showing top 20/1553 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARHGAP27 | SFTA2 | 0.866961 | 4 | 0 | 4 |
| ARHGAP27 | MPZL3 | 0.865932 | 8 | 0 | 8 |
| ARHGAP27 | SH3GL1 | 0.863987 | 7 | 0 | 7 |
| ARHGAP27 | IL36A | 0.86036 | 6 | 0 | 6 |
| ARHGAP27 | TTC9 | 0.858467 | 7 | 0 | 7 |
| ARHGAP27 | NIPAL1 | 0.853031 | 3 | 0 | 3 |
| ARHGAP27 | GYS2 | 0.852957 | 6 | 0 | 6 |
| ARHGAP27 | VSIG10L | 0.848194 | 6 | 0 | 6 |
| ARHGAP27 | TOM1 | 0.847638 | 7 | 0 | 7 |
| ARHGAP27 | SMIM5 | 0.847459 | 7 | 0 | 7 |
| ARHGAP27 | PADI1 | 0.847436 | 5 | 0 | 5 |
| ARHGAP27 | TMOD3 | 0.847404 | 7 | 0 | 7 |
| ARHGAP27 | RAET1E | 0.842986 | 6 | 0 | 6 |
| ARHGAP27 | USP6NL | 0.840459 | 7 | 0 | 7 |
| ARHGAP27 | PLEKHM1 | 0.839738 | 8 | 0 | 8 |
| ARHGAP27 | CHP1 | 0.837345 | 6 | 0 | 6 |
| ARHGAP27 | CCNG2 | 0.835981 | 7 | 0 | 7 |
| ARHGAP27 | EPGN | 0.835206 | 3 | 0 | 3 |
| ARHGAP27 | AIF1L | 0.834708 | 7 | 0 | 7 |
| ARHGAP27 | IKZF2 | 0.832353 | 7 | 0 | 7 |
For details and further investigation, click here
