| Full name: glycerophosphodiester phosphodiesterase domain containing 3 | Alias Symbol: MGC4171 | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 79153 | HGNC ID: HGNC:28638 | Ensembl Gene: ENSG00000102886 | OMIM ID: 616318 |
| Drug and gene relationship at DGIdb | |||
Expression of GDPD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GDPD3 | 79153 | 219722_s_at | -2.3487 | 0.0471 | |
| GSE20347 | GDPD3 | 79153 | 219722_s_at | -2.8154 | 0.0000 | |
| GSE23400 | GDPD3 | 79153 | 219722_s_at | -1.6017 | 0.0000 | |
| GSE26886 | GDPD3 | 79153 | 219722_s_at | -3.6892 | 0.0000 | |
| GSE29001 | GDPD3 | 79153 | 219722_s_at | -2.7497 | 0.0000 | |
| GSE38129 | GDPD3 | 79153 | 219722_s_at | -2.3317 | 0.0000 | |
| GSE45670 | GDPD3 | 79153 | 219722_s_at | -1.3444 | 0.0016 | |
| GSE53622 | GDPD3 | 79153 | 79836 | -3.1609 | 0.0000 | |
| GSE53624 | GDPD3 | 79153 | 79836 | -4.1760 | 0.0000 | |
| GSE63941 | GDPD3 | 79153 | 219722_s_at | 0.4507 | 0.4711 | |
| GSE77861 | GDPD3 | 79153 | 219722_s_at | -1.9578 | 0.0007 | |
| GSE97050 | GDPD3 | 79153 | A_23_P26511 | -0.8774 | 0.1313 | |
| SRP007169 | GDPD3 | 79153 | RNAseq | -5.7434 | 0.0000 | |
| SRP008496 | GDPD3 | 79153 | RNAseq | -5.2956 | 0.0000 | |
| SRP064894 | GDPD3 | 79153 | RNAseq | -2.9071 | 0.0000 | |
| SRP133303 | GDPD3 | 79153 | RNAseq | -3.4199 | 0.0000 | |
| SRP159526 | GDPD3 | 79153 | RNAseq | -2.9134 | 0.0000 | |
| SRP193095 | GDPD3 | 79153 | RNAseq | -3.1999 | 0.0000 | |
| SRP219564 | GDPD3 | 79153 | RNAseq | -2.8222 | 0.0000 | |
| TCGA | GDPD3 | 79153 | RNAseq | -0.5056 | 0.0768 |
Upregulated datasets: 0; Downregulated datasets: 17.
Survival by GDPD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GDPD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GDPD3 | 79153 | 5 | 5 | 20 | |
| GSE20123 | GDPD3 | 79153 | 5 | 4 | 21 | |
| GSE43470 | GDPD3 | 79153 | 3 | 3 | 37 | |
| GSE46452 | GDPD3 | 79153 | 38 | 1 | 20 | |
| GSE47630 | GDPD3 | 79153 | 11 | 7 | 22 | |
| GSE54993 | GDPD3 | 79153 | 2 | 5 | 63 | |
| GSE54994 | GDPD3 | 79153 | 5 | 9 | 39 | |
| GSE60625 | GDPD3 | 79153 | 4 | 0 | 7 | |
| GSE74703 | GDPD3 | 79153 | 3 | 2 | 31 | |
| GSE74704 | GDPD3 | 79153 | 3 | 2 | 15 | |
| TCGA | GDPD3 | 79153 | 20 | 11 | 65 |
Total number of gains: 99; Total number of losses: 49; Total Number of normals: 340.
Somatic mutations of GDPD3:
Generating mutation plots.
Highly correlated genes for GDPD3:
Showing top 20/1944 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GDPD3 | SCNN1B | 0.920182 | 11 | 0 | 11 |
| GDPD3 | CYSRT1 | 0.916913 | 7 | 0 | 7 |
| GDPD3 | MXD1 | 0.903361 | 11 | 0 | 11 |
| GDPD3 | GBP6 | 0.902888 | 4 | 0 | 4 |
| GDPD3 | IL36A | 0.897278 | 11 | 0 | 11 |
| GDPD3 | PADI1 | 0.889816 | 8 | 0 | 8 |
| GDPD3 | CES2 | 0.884924 | 9 | 0 | 9 |
| GDPD3 | ECM1 | 0.884824 | 12 | 0 | 12 |
| GDPD3 | CLIC3 | 0.881852 | 10 | 0 | 10 |
| GDPD3 | UPK1A | 0.881608 | 11 | 0 | 11 |
| GDPD3 | CRCT1 | 0.879472 | 12 | 0 | 12 |
| GDPD3 | RAET1E | 0.879234 | 7 | 0 | 7 |
| GDPD3 | FCHO2 | 0.87893 | 6 | 0 | 6 |
| GDPD3 | EPS8L1 | 0.877962 | 13 | 0 | 13 |
| GDPD3 | ENDOU | 0.877772 | 12 | 0 | 11 |
| GDPD3 | SLURP1 | 0.877225 | 12 | 0 | 11 |
| GDPD3 | RANBP9 | 0.873473 | 11 | 0 | 11 |
| GDPD3 | KRT78 | 0.870565 | 8 | 0 | 8 |
| GDPD3 | SLC46A2 | 0.870307 | 6 | 0 | 6 |
| GDPD3 | SNORA68 | 0.869212 | 4 | 0 | 4 |
For details and further investigation, click here
