| Full name: retinoic acid early transcript 1E | Alias Symbol: LETAL|bA350J20.7|ULBP4 | ||
| Type: protein-coding gene | Cytoband: 6q25.1 | ||
| Entrez ID: 135250 | HGNC ID: HGNC:16793 | Ensembl Gene: ENSG00000164520 | OMIM ID: 609243 |
| Drug and gene relationship at DGIdb | |||
RAET1E involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04650 | Natural killer cell mediated cytotoxicity |
Expression of RAET1E:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAET1E | 135250 | 1552777_a_at | -1.7984 | 0.0481 | |
| GSE26886 | RAET1E | 135250 | 1552777_a_at | -2.4852 | 0.0000 | |
| GSE45670 | RAET1E | 135250 | 1552777_a_at | -1.1003 | 0.0108 | |
| GSE53622 | RAET1E | 135250 | 82674 | -2.1835 | 0.0000 | |
| GSE53624 | RAET1E | 135250 | 82674 | -2.5907 | 0.0000 | |
| GSE63941 | RAET1E | 135250 | 1552777_a_at | 0.3772 | 0.3948 | |
| GSE77861 | RAET1E | 135250 | 1552777_a_at | -1.4670 | 0.0011 | |
| GSE97050 | RAET1E | 135250 | A_33_P3279847 | -0.2887 | 0.3432 | |
| SRP008496 | RAET1E | 135250 | RNAseq | -3.5956 | 0.0003 | |
| SRP064894 | RAET1E | 135250 | RNAseq | -3.7039 | 0.0000 | |
| SRP133303 | RAET1E | 135250 | RNAseq | -3.1383 | 0.0000 | |
| SRP159526 | RAET1E | 135250 | RNAseq | -5.5394 | 0.0000 | |
| SRP193095 | RAET1E | 135250 | RNAseq | -3.7282 | 0.0000 | |
| TCGA | RAET1E | 135250 | RNAseq | 0.2420 | 0.5824 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by RAET1E expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAET1E:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAET1E | 135250 | 2 | 4 | 24 | |
| GSE20123 | RAET1E | 135250 | 2 | 3 | 25 | |
| GSE43470 | RAET1E | 135250 | 4 | 0 | 39 | |
| GSE46452 | RAET1E | 135250 | 3 | 10 | 46 | |
| GSE47630 | RAET1E | 135250 | 9 | 4 | 27 | |
| GSE54993 | RAET1E | 135250 | 3 | 2 | 65 | |
| GSE54994 | RAET1E | 135250 | 8 | 8 | 37 | |
| GSE60625 | RAET1E | 135250 | 0 | 1 | 10 | |
| GSE74703 | RAET1E | 135250 | 4 | 0 | 32 | |
| GSE74704 | RAET1E | 135250 | 0 | 1 | 19 | |
| TCGA | RAET1E | 135250 | 11 | 21 | 64 |
Total number of gains: 46; Total number of losses: 54; Total Number of normals: 388.
Somatic mutations of RAET1E:
Generating mutation plots.
Highly correlated genes for RAET1E:
Showing top 20/1031 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAET1E | NCCRP1 | 0.913759 | 3 | 0 | 3 |
| RAET1E | CYSRT1 | 0.905541 | 6 | 0 | 6 |
| RAET1E | SFTA2 | 0.893266 | 4 | 0 | 4 |
| RAET1E | SPINK7 | 0.892056 | 7 | 0 | 7 |
| RAET1E | FAM163B | 0.885447 | 3 | 0 | 3 |
| RAET1E | VSIG10L | 0.880849 | 7 | 0 | 7 |
| RAET1E | GDPD3 | 0.879234 | 7 | 0 | 7 |
| RAET1E | GYS2 | 0.876218 | 6 | 0 | 6 |
| RAET1E | IL36A | 0.875895 | 7 | 0 | 7 |
| RAET1E | PRSS2 | 0.869398 | 5 | 0 | 5 |
| RAET1E | CRCT1 | 0.869143 | 7 | 0 | 7 |
| RAET1E | PPP1R3C | 0.868073 | 6 | 0 | 6 |
| RAET1E | CSTB | 0.861655 | 7 | 0 | 7 |
| RAET1E | CAPN14 | 0.855521 | 6 | 0 | 6 |
| RAET1E | SMIM5 | 0.852811 | 6 | 0 | 6 |
| RAET1E | CXCR2 | 0.851927 | 6 | 0 | 6 |
| RAET1E | TP53I3 | 0.85192 | 6 | 0 | 6 |
| RAET1E | RHCG | 0.850114 | 7 | 0 | 7 |
| RAET1E | C5orf66-AS1 | 0.849862 | 6 | 0 | 6 |
| RAET1E | HCG22 | 0.849541 | 6 | 0 | 6 |
For details and further investigation, click here
