| Full name: chromosome 1 open reading frame 116 | Alias Symbol: SARG|FLJ36507|MGC2742|MGC4309 | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 79098 | HGNC ID: HGNC:28667 | Ensembl Gene: ENSG00000182795 | OMIM ID: 611680 |
| Drug and gene relationship at DGIdb | |||
Expression of C1orf116:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C1orf116 | 79098 | 228865_at | -1.8171 | 0.2335 | |
| GSE20347 | C1orf116 | 79098 | 219476_at | -2.9678 | 0.0000 | |
| GSE23400 | C1orf116 | 79098 | 219476_at | -2.2384 | 0.0000 | |
| GSE26886 | C1orf116 | 79098 | 219476_at | -3.2335 | 0.0000 | |
| GSE29001 | C1orf116 | 79098 | 219476_at | -2.7378 | 0.0000 | |
| GSE38129 | C1orf116 | 79098 | 219476_at | -2.1763 | 0.0001 | |
| GSE45670 | C1orf116 | 79098 | 219476_at | -1.2315 | 0.0071 | |
| GSE53622 | C1orf116 | 79098 | 36944 | -2.6016 | 0.0000 | |
| GSE53624 | C1orf116 | 79098 | 36944 | -3.0449 | 0.0000 | |
| GSE63941 | C1orf116 | 79098 | 219476_at | 3.9535 | 0.0012 | |
| GSE77861 | C1orf116 | 79098 | 228865_at | -1.9824 | 0.0002 | |
| GSE97050 | C1orf116 | 79098 | A_23_P897 | -0.5908 | 0.6297 | |
| SRP007169 | C1orf116 | 79098 | RNAseq | -3.5967 | 0.0000 | |
| SRP008496 | C1orf116 | 79098 | RNAseq | -3.5413 | 0.0000 | |
| SRP064894 | C1orf116 | 79098 | RNAseq | -3.8261 | 0.0000 | |
| SRP133303 | C1orf116 | 79098 | RNAseq | -2.7132 | 0.0000 | |
| SRP159526 | C1orf116 | 79098 | RNAseq | -4.2089 | 0.0000 | |
| SRP193095 | C1orf116 | 79098 | RNAseq | -2.4894 | 0.0000 | |
| SRP219564 | C1orf116 | 79098 | RNAseq | -3.6363 | 0.0020 | |
| TCGA | C1orf116 | 79098 | RNAseq | -0.4285 | 0.0303 |
Upregulated datasets: 1; Downregulated datasets: 16.
Survival by C1orf116 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C1orf116:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C1orf116 | 79098 | 11 | 0 | 19 | |
| GSE20123 | C1orf116 | 79098 | 11 | 0 | 19 | |
| GSE43470 | C1orf116 | 79098 | 8 | 0 | 35 | |
| GSE46452 | C1orf116 | 79098 | 3 | 1 | 55 | |
| GSE47630 | C1orf116 | 79098 | 14 | 0 | 26 | |
| GSE54993 | C1orf116 | 79098 | 0 | 6 | 64 | |
| GSE54994 | C1orf116 | 79098 | 14 | 0 | 39 | |
| GSE60625 | C1orf116 | 79098 | 0 | 0 | 11 | |
| GSE74703 | C1orf116 | 79098 | 8 | 0 | 28 | |
| GSE74704 | C1orf116 | 79098 | 5 | 0 | 15 | |
| TCGA | C1orf116 | 79098 | 45 | 3 | 48 |
Total number of gains: 119; Total number of losses: 10; Total Number of normals: 359.
Somatic mutations of C1orf116:
Generating mutation plots.
Highly correlated genes for C1orf116:
Showing top 20/1522 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C1orf116 | MALL | 0.869778 | 12 | 0 | 12 |
| C1orf116 | IL18 | 0.857817 | 11 | 0 | 11 |
| C1orf116 | EPS8L1 | 0.850018 | 13 | 0 | 13 |
| C1orf116 | EPS8L2 | 0.846358 | 11 | 0 | 11 |
| C1orf116 | HOPX | 0.846178 | 12 | 0 | 12 |
| C1orf116 | PADI1 | 0.843308 | 9 | 0 | 9 |
| C1orf116 | GBP6 | 0.842975 | 4 | 0 | 4 |
| C1orf116 | PPL | 0.842302 | 13 | 0 | 13 |
| C1orf116 | FCHO2 | 0.841749 | 6 | 0 | 6 |
| C1orf116 | VSIG2 | 0.841357 | 7 | 0 | 7 |
| C1orf116 | CHP1 | 0.839333 | 10 | 0 | 10 |
| C1orf116 | GYS2 | 0.838575 | 10 | 0 | 10 |
| C1orf116 | CLIC3 | 0.837692 | 10 | 0 | 10 |
| C1orf116 | UPK3B | 0.837262 | 3 | 0 | 3 |
| C1orf116 | CWH43 | 0.834984 | 10 | 0 | 10 |
| C1orf116 | AIF1L | 0.833949 | 8 | 0 | 8 |
| C1orf116 | SERPINB1 | 0.832191 | 12 | 0 | 12 |
| C1orf116 | TMEM154 | 0.829839 | 8 | 0 | 8 |
| C1orf116 | PDCD6IP | 0.827033 | 10 | 0 | 10 |
| C1orf116 | TTC9 | 0.826006 | 11 | 0 | 11 |
For details and further investigation, click here
