| Full name: mal, T cell differentiation protein | Alias Symbol: MVP17|VIP17 | ||
| Type: protein-coding gene | Cytoband: 2q11.1 | ||
| Entrez ID: 4118 | HGNC ID: HGNC:6817 | Ensembl Gene: ENSG00000172005 | OMIM ID: 188860 |
| Drug and gene relationship at DGIdb | |||
Expression of MAL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAL | 4118 | 204777_s_at | -4.7155 | 0.0274 | |
| GSE20347 | MAL | 4118 | 204777_s_at | -5.6677 | 0.0000 | |
| GSE23400 | MAL | 4118 | 204777_s_at | -4.8818 | 0.0000 | |
| GSE26886 | MAL | 4118 | 204777_s_at | -8.9163 | 0.0000 | |
| GSE29001 | MAL | 4118 | 204777_s_at | -5.3341 | 0.0000 | |
| GSE38129 | MAL | 4118 | 204777_s_at | -4.9391 | 0.0000 | |
| GSE45670 | MAL | 4118 | 204777_s_at | -1.8871 | 0.0526 | |
| GSE53622 | MAL | 4118 | 8994 | -4.7053 | 0.0000 | |
| GSE53624 | MAL | 4118 | 8994 | -4.7867 | 0.0000 | |
| GSE63941 | MAL | 4118 | 204777_s_at | 0.2057 | 0.3311 | |
| GSE77861 | MAL | 4118 | 204777_s_at | -4.3088 | 0.0275 | |
| GSE97050 | MAL | 4118 | A_23_P17134 | -3.8366 | 0.0454 | |
| SRP007169 | MAL | 4118 | RNAseq | -11.0396 | 0.0000 | |
| SRP008496 | MAL | 4118 | RNAseq | -8.7857 | 0.0000 | |
| SRP064894 | MAL | 4118 | RNAseq | -5.6045 | 0.0000 | |
| SRP133303 | MAL | 4118 | RNAseq | -7.2171 | 0.0000 | |
| SRP159526 | MAL | 4118 | RNAseq | -7.7709 | 0.0000 | |
| SRP193095 | MAL | 4118 | RNAseq | -6.1738 | 0.0000 | |
| SRP219564 | MAL | 4118 | RNAseq | -5.4849 | 0.0000 | |
| TCGA | MAL | 4118 | RNAseq | -1.1718 | 0.0201 |
Upregulated datasets: 0; Downregulated datasets: 18.
Survival by MAL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MAL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAL | 4118 | 8 | 1 | 21 | |
| GSE20123 | MAL | 4118 | 8 | 1 | 21 | |
| GSE43470 | MAL | 4118 | 3 | 2 | 38 | |
| GSE46452 | MAL | 4118 | 2 | 3 | 54 | |
| GSE47630 | MAL | 4118 | 7 | 0 | 33 | |
| GSE54993 | MAL | 4118 | 0 | 6 | 64 | |
| GSE54994 | MAL | 4118 | 11 | 0 | 42 | |
| GSE60625 | MAL | 4118 | 0 | 3 | 8 | |
| GSE74703 | MAL | 4118 | 3 | 1 | 32 | |
| GSE74704 | MAL | 4118 | 5 | 0 | 15 | |
| TCGA | MAL | 4118 | 35 | 5 | 56 |
Total number of gains: 82; Total number of losses: 22; Total Number of normals: 384.
Somatic mutations of MAL:
Generating mutation plots.
Highly correlated genes for MAL:
Showing top 20/1621 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAL | CRNN | 0.951024 | 12 | 0 | 12 |
| MAL | TMPRSS11B | 0.939487 | 8 | 0 | 8 |
| MAL | KRT4 | 0.904926 | 12 | 0 | 12 |
| MAL | PRSS27 | 0.900837 | 8 | 0 | 8 |
| MAL | SPINK7 | 0.891392 | 8 | 0 | 8 |
| MAL | TGM3 | 0.887538 | 12 | 0 | 12 |
| MAL | SPINK5 | 0.877191 | 13 | 0 | 12 |
| MAL | KRT13 | 0.874534 | 12 | 0 | 12 |
| MAL | SLURP1 | 0.873946 | 13 | 0 | 13 |
| MAL | VSIG10L | 0.871872 | 7 | 0 | 7 |
| MAL | CLCA4 | 0.870282 | 13 | 0 | 12 |
| MAL | C5orf66-AS1 | 0.868394 | 6 | 0 | 6 |
| MAL | ENDOU | 0.868018 | 11 | 0 | 11 |
| MAL | ECM1 | 0.867174 | 12 | 0 | 12 |
| MAL | CLIC3 | 0.863204 | 10 | 0 | 10 |
| MAL | NCR1 | 0.862124 | 3 | 0 | 3 |
| MAL | CYSRT1 | 0.858847 | 7 | 0 | 7 |
| MAL | SCEL | 0.855303 | 13 | 0 | 12 |
| MAL | FAM214A | 0.85363 | 6 | 0 | 6 |
| MAL | EPS8L2 | 0.852868 | 11 | 0 | 11 |
For details and further investigation, click here
