GOLGA8A

 

Full name: golgin A8 family member A Alias Symbol: GM88|GOLGIN-67
Type: protein-coding gene Cytoband: 15q14
Entrez ID: 23015 HGNC ID: HGNC:31972 Ensembl Gene: ENSG00000175265 OMIM ID: 616180
Drug and gene relationship at DGIdb

 

Expression of GOLGA8A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GOLGA8A 23015 208798_x_at 0.1924 0.7140
GSE20347 GOLGA8A 23015 208798_x_at 0.5114 0.1887
GSE23400 GOLGA8A 23015 208798_x_at 0.4309 0.0015
GSE26886 GOLGA8A 23015 208798_x_at -0.1170 0.7721
GSE29001 GOLGA8A 23015 208798_x_at 0.2383 0.6069
GSE38129 GOLGA8A 23015 208798_x_at 0.2776 0.3930
GSE45670 GOLGA8A 23015 208798_x_at -0.2788 0.2368
GSE53622 GOLGA8A 23015 32156 -0.3580 0.0000
GSE53624 GOLGA8A 23015 32156 -0.4755 0.0000
GSE63941 GOLGA8A 23015 208798_x_at -0.4628 0.5823
GSE77861 GOLGA8A 23015 208798_x_at 0.4552 0.4006
GSE97050 GOLGA8A 23015 A_23_P37623 0.0607 0.7895
SRP007169 GOLGA8A 23015 RNAseq 1.3329 0.0154
SRP008496 GOLGA8A 23015 RNAseq 1.8189 0.0000
SRP064894 GOLGA8A 23015 RNAseq -0.0953 0.7584
SRP133303 GOLGA8A 23015 RNAseq 0.0808 0.6834
SRP159526 GOLGA8A 23015 RNAseq 0.1694 0.5667
SRP193095 GOLGA8A 23015 RNAseq 0.4134 0.0446
SRP219564 GOLGA8A 23015 RNAseq -0.4238 0.2847
TCGA GOLGA8A 23015 RNAseq -0.0300 0.7275

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by GOLGA8A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GOLGA8A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GOLGA8A 23015 3 6 21
GSE20123 GOLGA8A 23015 3 6 21
GSE43470 GOLGA8A 23015 4 4 35
GSE46452 GOLGA8A 23015 3 7 49
GSE47630 GOLGA8A 23015 8 11 21
GSE54993 GOLGA8A 23015 4 6 60
GSE54994 GOLGA8A 23015 5 8 40
GSE60625 GOLGA8A 23015 4 0 7
GSE74703 GOLGA8A 23015 4 3 29
GSE74704 GOLGA8A 23015 2 5 13
TCGA GOLGA8A 23015 14 17 65

Total number of gains: 54; Total number of losses: 73; Total Number of normals: 361.  


 

Somatic mutations of GOLGA8A:

 

Generating mutation plots.

 

Highly correlated genes for GOLGA8A:

 

Showing top 20/173 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GOLGA8AANKRD170.744517303
GOLGA8ATRAPPC100.741753404
GOLGA8AAKAP17A0.740999404
GOLGA8ARFX10.740806303
GOLGA8ARAPGEF10.732554303
GOLGA8AFAM193A0.727261303
GOLGA8AZNF4510.726938404
GOLGA8ALRP5L0.719426303
GOLGA8AZNF3970.712675303
GOLGA8AERGIC10.703302303
GOLGA8ASLC25A190.701186303
GOLGA8AUSP210.700401404
GOLGA8AHEXA0.696234403
GOLGA8AIMPDH10.694481303
GOLGA8AZNF5670.69082303
GOLGA8ATRMT2A0.687973303
GOLGA8AZNF2510.679813303
GOLGA8AZFYVE270.675832403
GOLGA8AGNA110.674939303
GOLGA8AANKRD270.672126403

For details and further investigation, click here