| Full name: zinc finger FYVE-type containing 27 | Alias Symbol: FLJ32919|SPG33 | ||
| Type: protein-coding gene | Cytoband: 10q24.2 | ||
| Entrez ID: 118813 | HGNC ID: HGNC:26559 | Ensembl Gene: ENSG00000155256 | OMIM ID: 610243 |
| Drug and gene relationship at DGIdb | |||
Expression of ZFYVE27:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZFYVE27 | 118813 | 225218_at | 0.3091 | 0.3930 | |
| GSE26886 | ZFYVE27 | 118813 | 225218_at | 0.5154 | 0.0079 | |
| GSE45670 | ZFYVE27 | 118813 | 225218_at | 0.1812 | 0.0570 | |
| GSE53622 | ZFYVE27 | 118813 | 110367 | -0.0081 | 0.9530 | |
| GSE53624 | ZFYVE27 | 118813 | 7684 | 0.2799 | 0.0001 | |
| GSE63941 | ZFYVE27 | 118813 | 225218_at | 0.1031 | 0.7825 | |
| GSE77861 | ZFYVE27 | 118813 | 225218_at | 0.2672 | 0.1505 | |
| GSE97050 | ZFYVE27 | 118813 | A_23_P323924 | 0.3577 | 0.2092 | |
| SRP007169 | ZFYVE27 | 118813 | RNAseq | -0.1939 | 0.6627 | |
| SRP008496 | ZFYVE27 | 118813 | RNAseq | 0.1777 | 0.5648 | |
| SRP064894 | ZFYVE27 | 118813 | RNAseq | 0.1116 | 0.3218 | |
| SRP133303 | ZFYVE27 | 118813 | RNAseq | 0.1852 | 0.2683 | |
| SRP159526 | ZFYVE27 | 118813 | RNAseq | -0.1010 | 0.6470 | |
| SRP193095 | ZFYVE27 | 118813 | RNAseq | 0.1838 | 0.1044 | |
| SRP219564 | ZFYVE27 | 118813 | RNAseq | 0.4561 | 0.2969 | |
| TCGA | ZFYVE27 | 118813 | RNAseq | -0.1274 | 0.0221 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZFYVE27 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZFYVE27:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZFYVE27 | 118813 | 1 | 8 | 21 | |
| GSE20123 | ZFYVE27 | 118813 | 1 | 7 | 22 | |
| GSE43470 | ZFYVE27 | 118813 | 0 | 7 | 36 | |
| GSE46452 | ZFYVE27 | 118813 | 0 | 11 | 48 | |
| GSE47630 | ZFYVE27 | 118813 | 2 | 14 | 24 | |
| GSE54993 | ZFYVE27 | 118813 | 8 | 0 | 62 | |
| GSE54994 | ZFYVE27 | 118813 | 2 | 11 | 40 | |
| GSE60625 | ZFYVE27 | 118813 | 0 | 0 | 11 | |
| GSE74703 | ZFYVE27 | 118813 | 0 | 5 | 31 | |
| GSE74704 | ZFYVE27 | 118813 | 0 | 4 | 16 | |
| TCGA | ZFYVE27 | 118813 | 5 | 28 | 63 |
Total number of gains: 19; Total number of losses: 95; Total Number of normals: 374.
Somatic mutations of ZFYVE27:
Generating mutation plots.
Highly correlated genes for ZFYVE27:
Showing top 20/769 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZFYVE27 | TMTC4 | 0.895654 | 3 | 0 | 3 |
| ZFYVE27 | ZBTB39 | 0.8448 | 3 | 0 | 3 |
| ZFYVE27 | ZNF202 | 0.839356 | 3 | 0 | 3 |
| ZFYVE27 | MIA3 | 0.838285 | 3 | 0 | 3 |
| ZFYVE27 | SARS2 | 0.827851 | 3 | 0 | 3 |
| ZFYVE27 | RFNG | 0.816009 | 3 | 0 | 3 |
| ZFYVE27 | MEA1 | 0.801579 | 3 | 0 | 3 |
| ZFYVE27 | THEM4 | 0.794239 | 3 | 0 | 3 |
| ZFYVE27 | UXS1 | 0.783398 | 3 | 0 | 3 |
| ZFYVE27 | RPL7L1 | 0.77723 | 3 | 0 | 3 |
| ZFYVE27 | ZNF507 | 0.771274 | 3 | 0 | 3 |
| ZFYVE27 | FIP1L1 | 0.768859 | 3 | 0 | 3 |
| ZFYVE27 | HYLS1 | 0.766778 | 3 | 0 | 3 |
| ZFYVE27 | MTHFSD | 0.764117 | 3 | 0 | 3 |
| ZFYVE27 | TARBP1 | 0.759997 | 3 | 0 | 3 |
| ZFYVE27 | DDX11 | 0.759637 | 4 | 0 | 4 |
| ZFYVE27 | ANKRD10 | 0.758797 | 3 | 0 | 3 |
| ZFYVE27 | JMJD4 | 0.754261 | 3 | 0 | 3 |
| ZFYVE27 | DOCK6 | 0.752472 | 3 | 0 | 3 |
| ZFYVE27 | PIGC | 0.75229 | 3 | 0 | 3 |
For details and further investigation, click here
