| Full name: nucleolar protein with MIF4G domain 1 | Alias Symbol: SGD1|PPP1R113 | ||
| Type: protein-coding gene | Cytoband: 7q36.3 | ||
| Entrez ID: 64434 | HGNC ID: HGNC:13244 | Ensembl Gene: ENSG00000146909 | OMIM ID: 611269 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NOM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOM1 | 64434 | 229220_x_at | 0.6130 | 0.3042 | |
| GSE26886 | NOM1 | 64434 | 229220_x_at | 0.4784 | 0.0274 | |
| GSE45670 | NOM1 | 64434 | 229220_x_at | 0.2666 | 0.0774 | |
| GSE53622 | NOM1 | 64434 | 110552 | 0.0213 | 0.8424 | |
| GSE53624 | NOM1 | 64434 | 110552 | 0.3125 | 0.0000 | |
| GSE63941 | NOM1 | 64434 | 229220_x_at | 0.3049 | 0.1971 | |
| GSE77861 | NOM1 | 64434 | 229220_x_at | 0.4557 | 0.0057 | |
| GSE97050 | NOM1 | 64434 | A_33_P3378430 | -0.0925 | 0.7536 | |
| SRP007169 | NOM1 | 64434 | RNAseq | 1.9826 | 0.0004 | |
| SRP008496 | NOM1 | 64434 | RNAseq | 1.5709 | 0.0002 | |
| SRP064894 | NOM1 | 64434 | RNAseq | 0.2623 | 0.1461 | |
| SRP133303 | NOM1 | 64434 | RNAseq | 0.3177 | 0.1014 | |
| SRP159526 | NOM1 | 64434 | RNAseq | -0.1163 | 0.7175 | |
| SRP193095 | NOM1 | 64434 | RNAseq | 0.3125 | 0.0076 | |
| SRP219564 | NOM1 | 64434 | RNAseq | 0.0541 | 0.8829 | |
| TCGA | NOM1 | 64434 | RNAseq | 0.0279 | 0.6275 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by NOM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NOM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOM1 | 64434 | 4 | 3 | 23 | |
| GSE20123 | NOM1 | 64434 | 3 | 3 | 24 | |
| GSE43470 | NOM1 | 64434 | 2 | 5 | 36 | |
| GSE46452 | NOM1 | 64434 | 7 | 2 | 50 | |
| GSE47630 | NOM1 | 64434 | 6 | 9 | 25 | |
| GSE54993 | NOM1 | 64434 | 3 | 3 | 64 | |
| GSE54994 | NOM1 | 64434 | 6 | 8 | 39 | |
| GSE60625 | NOM1 | 64434 | 0 | 0 | 11 | |
| GSE74703 | NOM1 | 64434 | 2 | 4 | 30 | |
| GSE74704 | NOM1 | 64434 | 1 | 3 | 16 | |
| TCGA | NOM1 | 64434 | 27 | 25 | 44 |
Total number of gains: 61; Total number of losses: 65; Total Number of normals: 362.
Somatic mutations of NOM1:
Generating mutation plots.
Highly correlated genes for NOM1:
Showing top 20/974 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOM1 | TMEM135 | 0.836062 | 3 | 0 | 3 |
| NOM1 | PRKCI | 0.823614 | 3 | 0 | 3 |
| NOM1 | CPNE8 | 0.818588 | 3 | 0 | 3 |
| NOM1 | DCAF16 | 0.802507 | 3 | 0 | 3 |
| NOM1 | CTBP2 | 0.794186 | 4 | 0 | 4 |
| NOM1 | RAVER1 | 0.788291 | 3 | 0 | 3 |
| NOM1 | ANKRD17 | 0.787746 | 3 | 0 | 3 |
| NOM1 | ZNF140 | 0.785197 | 3 | 0 | 3 |
| NOM1 | MAP4K3 | 0.780999 | 3 | 0 | 3 |
| NOM1 | SCRN1 | 0.780202 | 3 | 0 | 3 |
| NOM1 | TMEM181 | 0.777421 | 3 | 0 | 3 |
| NOM1 | CPT1A | 0.777308 | 3 | 0 | 3 |
| NOM1 | ZNF268 | 0.776929 | 3 | 0 | 3 |
| NOM1 | FBXO33 | 0.774608 | 3 | 0 | 3 |
| NOM1 | THOC1 | 0.77303 | 3 | 0 | 3 |
| NOM1 | ZFP30 | 0.77109 | 3 | 0 | 3 |
| NOM1 | NAP1L1 | 0.766855 | 3 | 0 | 3 |
| NOM1 | DSCC1 | 0.764829 | 4 | 0 | 4 |
| NOM1 | ZBTB44 | 0.762622 | 3 | 0 | 3 |
| NOM1 | ZNF791 | 0.76004 | 3 | 0 | 3 |
For details and further investigation, click here
