| Full name: methyltransferase like 9 | Alias Symbol: DREV1 | ||
| Type: protein-coding gene | Cytoband: 16p12.2 | ||
| Entrez ID: 51108 | HGNC ID: HGNC:24586 | Ensembl Gene: ENSG00000197006 | OMIM ID: 609388 |
| Drug and gene relationship at DGIdb | |||
Expression of METTL9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | METTL9 | 51108 | 217868_s_at | -0.1361 | 0.7814 | |
| GSE20347 | METTL9 | 51108 | 217868_s_at | -0.5562 | 0.0002 | |
| GSE23400 | METTL9 | 51108 | 217868_s_at | -0.1146 | 0.1195 | |
| GSE26886 | METTL9 | 51108 | 217868_s_at | -0.3863 | 0.0175 | |
| GSE29001 | METTL9 | 51108 | 217868_s_at | -0.5492 | 0.0869 | |
| GSE38129 | METTL9 | 51108 | 217868_s_at | -0.2717 | 0.0246 | |
| GSE45670 | METTL9 | 51108 | 217868_s_at | -0.1740 | 0.2341 | |
| GSE53622 | METTL9 | 51108 | 138189 | -0.4068 | 0.0000 | |
| GSE53624 | METTL9 | 51108 | 138189 | -0.4009 | 0.0000 | |
| GSE63941 | METTL9 | 51108 | 217868_s_at | -0.4119 | 0.2370 | |
| GSE77861 | METTL9 | 51108 | 217868_s_at | -0.3923 | 0.3178 | |
| GSE97050 | METTL9 | 51108 | A_24_P202139 | -0.4135 | 0.2660 | |
| SRP007169 | METTL9 | 51108 | RNAseq | -1.3435 | 0.0002 | |
| SRP008496 | METTL9 | 51108 | RNAseq | -1.0763 | 0.0000 | |
| SRP064894 | METTL9 | 51108 | RNAseq | -0.6963 | 0.0000 | |
| SRP133303 | METTL9 | 51108 | RNAseq | -0.1073 | 0.4404 | |
| SRP159526 | METTL9 | 51108 | RNAseq | -0.4243 | 0.1127 | |
| SRP193095 | METTL9 | 51108 | RNAseq | -0.7888 | 0.0000 | |
| SRP219564 | METTL9 | 51108 | RNAseq | -0.5407 | 0.1628 | |
| TCGA | METTL9 | 51108 | RNAseq | -0.0247 | 0.5713 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by METTL9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of METTL9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | METTL9 | 51108 | 6 | 3 | 21 | |
| GSE20123 | METTL9 | 51108 | 6 | 2 | 22 | |
| GSE43470 | METTL9 | 51108 | 3 | 3 | 37 | |
| GSE46452 | METTL9 | 51108 | 38 | 1 | 20 | |
| GSE47630 | METTL9 | 51108 | 11 | 6 | 23 | |
| GSE54993 | METTL9 | 51108 | 3 | 5 | 62 | |
| GSE54994 | METTL9 | 51108 | 4 | 10 | 39 | |
| GSE60625 | METTL9 | 51108 | 4 | 0 | 7 | |
| GSE74703 | METTL9 | 51108 | 3 | 2 | 31 | |
| GSE74704 | METTL9 | 51108 | 3 | 1 | 16 | |
| TCGA | METTL9 | 51108 | 19 | 13 | 64 |
Total number of gains: 100; Total number of losses: 46; Total Number of normals: 342.
Somatic mutations of METTL9:
Generating mutation plots.
Highly correlated genes for METTL9:
Showing top 20/809 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| METTL9 | EIF1B | 0.771819 | 3 | 0 | 3 |
| METTL9 | FAM83D | 0.767602 | 3 | 0 | 3 |
| METTL9 | CCDC90B | 0.73708 | 6 | 0 | 6 |
| METTL9 | AMOTL1 | 0.734466 | 3 | 0 | 3 |
| METTL9 | DPH3 | 0.733798 | 3 | 0 | 3 |
| METTL9 | SLC30A4 | 0.724882 | 3 | 0 | 3 |
| METTL9 | NSMCE1 | 0.72336 | 3 | 0 | 3 |
| METTL9 | SPRYD4 | 0.720902 | 3 | 0 | 3 |
| METTL9 | SERINC1 | 0.717486 | 4 | 0 | 4 |
| METTL9 | RIOK2 | 0.715794 | 3 | 0 | 3 |
| METTL9 | C16orf72 | 0.70959 | 3 | 0 | 3 |
| METTL9 | COPS4 | 0.70695 | 7 | 0 | 6 |
| METTL9 | ZFAND5 | 0.706053 | 3 | 0 | 3 |
| METTL9 | SENP6 | 0.705977 | 3 | 0 | 3 |
| METTL9 | KEL | 0.701282 | 3 | 0 | 3 |
| METTL9 | FRMD6 | 0.693261 | 3 | 0 | 3 |
| METTL9 | UXT | 0.691576 | 4 | 0 | 4 |
| METTL9 | ITGA2 | 0.687604 | 3 | 0 | 3 |
| METTL9 | TBC1D20 | 0.685951 | 4 | 0 | 3 |
| METTL9 | EIF4G2 | 0.685391 | 6 | 0 | 4 |
For details and further investigation, click here
