| Full name: family with sequence similarity 89 member A | Alias Symbol: MGC15887 | ||
| Type: protein-coding gene | Cytoband: 1q42.2 | ||
| Entrez ID: 375061 | HGNC ID: HGNC:25057 | Ensembl Gene: ENSG00000182118 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of FAM89A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | FAM89A | 375061 | 24374 | 1.6540 | 0.0000 | |
| GSE53624 | FAM89A | 375061 | 24374 | 1.9564 | 0.0000 | |
| GSE97050 | FAM89A | 375061 | A_24_P418408 | 1.1513 | 0.0620 | |
| SRP007169 | FAM89A | 375061 | RNAseq | 2.3623 | 0.0002 | |
| SRP008496 | FAM89A | 375061 | RNAseq | 2.8016 | 0.0000 | |
| SRP064894 | FAM89A | 375061 | RNAseq | 1.7985 | 0.0000 | |
| SRP133303 | FAM89A | 375061 | RNAseq | 1.7458 | 0.0000 | |
| SRP159526 | FAM89A | 375061 | RNAseq | 2.3967 | 0.0002 | |
| SRP193095 | FAM89A | 375061 | RNAseq | 2.0043 | 0.0000 | |
| SRP219564 | FAM89A | 375061 | RNAseq | 0.8250 | 0.1731 | |
| TCGA | FAM89A | 375061 | RNAseq | 0.5973 | 0.0000 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by FAM89A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM89A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM89A | 375061 | 11 | 0 | 19 | |
| GSE20123 | FAM89A | 375061 | 11 | 0 | 19 | |
| GSE43470 | FAM89A | 375061 | 8 | 1 | 34 | |
| GSE46452 | FAM89A | 375061 | 4 | 2 | 53 | |
| GSE47630 | FAM89A | 375061 | 15 | 0 | 25 | |
| GSE54993 | FAM89A | 375061 | 0 | 6 | 64 | |
| GSE54994 | FAM89A | 375061 | 17 | 0 | 36 | |
| GSE60625 | FAM89A | 375061 | 0 | 0 | 11 | |
| GSE74703 | FAM89A | 375061 | 8 | 1 | 27 | |
| GSE74704 | FAM89A | 375061 | 5 | 0 | 15 | |
| TCGA | FAM89A | 375061 | 44 | 4 | 48 |
Total number of gains: 123; Total number of losses: 14; Total Number of normals: 351.
Somatic mutations of FAM89A:
Generating mutation plots.
Highly correlated genes for FAM89A:
Showing top 20/687 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM89A | SHC1 | 0.839467 | 3 | 0 | 3 |
| FAM89A | MET | 0.832353 | 3 | 0 | 3 |
| FAM89A | MTHFD1L | 0.828658 | 3 | 0 | 3 |
| FAM89A | FJX1 | 0.817853 | 3 | 0 | 3 |
| FAM89A | LRP12 | 0.808349 | 3 | 0 | 3 |
| FAM89A | PTDSS1 | 0.804696 | 3 | 0 | 3 |
| FAM89A | ITPR3 | 0.803124 | 3 | 0 | 3 |
| FAM89A | DDX39A | 0.801673 | 3 | 0 | 3 |
| FAM89A | ZNF469 | 0.800058 | 3 | 0 | 3 |
| FAM89A | WDHD1 | 0.796616 | 3 | 0 | 3 |
| FAM89A | MMP3 | 0.796531 | 3 | 0 | 3 |
| FAM89A | ANLN | 0.795868 | 3 | 0 | 3 |
| FAM89A | ANGPT2 | 0.787477 | 3 | 0 | 3 |
| FAM89A | SERPINE1 | 0.786792 | 3 | 0 | 3 |
| FAM89A | TFRC | 0.784171 | 3 | 0 | 3 |
| FAM89A | ESM1 | 0.782715 | 3 | 0 | 3 |
| FAM89A | ACTL6A | 0.780665 | 3 | 0 | 3 |
| FAM89A | ILF2 | 0.778117 | 3 | 0 | 3 |
| FAM89A | IFI16 | 0.77795 | 3 | 0 | 3 |
| FAM89A | SLC26A6 | 0.777943 | 3 | 0 | 3 |
For details and further investigation, click here
