| Full name: transmembrane protein 216 | Alias Symbol: MGC13379|HSPC244|JBTS2 | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 51259 | HGNC ID: HGNC:25018 | Ensembl Gene: ENSG00000187049 | OMIM ID: 613277 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM216:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM216 | 51259 | 223305_at | 0.1796 | 0.6021 | |
| GSE26886 | TMEM216 | 51259 | 223305_at | 0.8761 | 0.0000 | |
| GSE45670 | TMEM216 | 51259 | 223305_at | 0.1580 | 0.4936 | |
| GSE53622 | TMEM216 | 51259 | 86483 | 0.1106 | 0.2545 | |
| GSE53624 | TMEM216 | 51259 | 86483 | 0.3674 | 0.0010 | |
| GSE63941 | TMEM216 | 51259 | 223305_at | -0.1930 | 0.8956 | |
| GSE77861 | TMEM216 | 51259 | 223305_at | 0.3685 | 0.1303 | |
| GSE97050 | TMEM216 | 51259 | A_33_P3221868 | 0.1783 | 0.6481 | |
| SRP007169 | TMEM216 | 51259 | RNAseq | 0.8151 | 0.1400 | |
| SRP008496 | TMEM216 | 51259 | RNAseq | 1.0551 | 0.0021 | |
| SRP064894 | TMEM216 | 51259 | RNAseq | 0.5162 | 0.0321 | |
| SRP133303 | TMEM216 | 51259 | RNAseq | 0.2376 | 0.2898 | |
| SRP159526 | TMEM216 | 51259 | RNAseq | 0.9607 | 0.0000 | |
| SRP193095 | TMEM216 | 51259 | RNAseq | 0.0868 | 0.5884 | |
| SRP219564 | TMEM216 | 51259 | RNAseq | 0.1831 | 0.7511 | |
| TCGA | TMEM216 | 51259 | RNAseq | 0.1727 | 0.0349 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TMEM216 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM216:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM216 | 51259 | 4 | 5 | 21 | |
| GSE20123 | TMEM216 | 51259 | 4 | 5 | 21 | |
| GSE43470 | TMEM216 | 51259 | 2 | 6 | 35 | |
| GSE46452 | TMEM216 | 51259 | 8 | 4 | 47 | |
| GSE47630 | TMEM216 | 51259 | 3 | 8 | 29 | |
| GSE54993 | TMEM216 | 51259 | 3 | 0 | 67 | |
| GSE54994 | TMEM216 | 51259 | 5 | 5 | 43 | |
| GSE60625 | TMEM216 | 51259 | 0 | 3 | 8 | |
| GSE74703 | TMEM216 | 51259 | 2 | 3 | 31 | |
| GSE74704 | TMEM216 | 51259 | 3 | 3 | 14 | |
| TCGA | TMEM216 | 51259 | 15 | 10 | 71 |
Total number of gains: 49; Total number of losses: 52; Total Number of normals: 387.
Somatic mutations of TMEM216:
Generating mutation plots.
Highly correlated genes for TMEM216:
Showing top 20/975 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM216 | XPO5 | 0.784936 | 3 | 0 | 3 |
| TMEM216 | LSM7 | 0.778468 | 4 | 0 | 4 |
| TMEM216 | LSM4 | 0.774112 | 4 | 0 | 4 |
| TMEM216 | OSR2 | 0.770395 | 3 | 0 | 3 |
| TMEM216 | ATG4C | 0.764569 | 3 | 0 | 3 |
| TMEM216 | BRAT1 | 0.75254 | 3 | 0 | 3 |
| TMEM216 | EMG1 | 0.751365 | 3 | 0 | 3 |
| TMEM216 | RUNX3 | 0.74927 | 3 | 0 | 3 |
| TMEM216 | LRRC34 | 0.747452 | 4 | 0 | 4 |
| TMEM216 | RAD54L | 0.744918 | 3 | 0 | 3 |
| TMEM216 | ZFPL1 | 0.740825 | 3 | 0 | 3 |
| TMEM216 | MSTO1 | 0.737636 | 3 | 0 | 3 |
| TMEM216 | RPL35A | 0.735719 | 3 | 0 | 3 |
| TMEM216 | MAGOHB | 0.735343 | 4 | 0 | 4 |
| TMEM216 | FARSA | 0.734533 | 4 | 0 | 4 |
| TMEM216 | ZNF367 | 0.734135 | 3 | 0 | 3 |
| TMEM216 | TYW1 | 0.730403 | 3 | 0 | 3 |
| TMEM216 | KRT18 | 0.72822 | 3 | 0 | 3 |
| TMEM216 | NOP2 | 0.728128 | 4 | 0 | 4 |
| TMEM216 | IGF1R | 0.727642 | 3 | 0 | 3 |
For details and further investigation, click here
