| Full name: chromosome 12 open reading frame 57 | Alias Symbol: GRCC10|C10 | ||
| Type: protein-coding gene | Cytoband: 12p13.31 | ||
| Entrez ID: 113246 | HGNC ID: HGNC:29521 | Ensembl Gene: ENSG00000111678 | OMIM ID: 615140 |
| Drug and gene relationship at DGIdb | |||
Expression of C12orf57:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C12orf57 | 113246 | 224719_s_at | -0.1242 | 0.9050 | |
| GSE26886 | C12orf57 | 113246 | 224719_s_at | 1.7901 | 0.0000 | |
| GSE45670 | C12orf57 | 113246 | 224719_s_at | -0.3387 | 0.2010 | |
| GSE53622 | C12orf57 | 113246 | 118329 | 0.2388 | 0.0119 | |
| GSE53624 | C12orf57 | 113246 | 118329 | 0.4651 | 0.0000 | |
| GSE63941 | C12orf57 | 113246 | 224719_s_at | 0.2199 | 0.7232 | |
| GSE77861 | C12orf57 | 113246 | 224719_s_at | 0.7209 | 0.0402 | |
| GSE97050 | C12orf57 | 113246 | A_23_P350551 | -0.2878 | 0.2277 | |
| SRP007169 | C12orf57 | 113246 | RNAseq | 0.1788 | 0.6720 | |
| SRP008496 | C12orf57 | 113246 | RNAseq | 0.2041 | 0.5228 | |
| SRP064894 | C12orf57 | 113246 | RNAseq | 0.5876 | 0.2032 | |
| SRP133303 | C12orf57 | 113246 | RNAseq | 0.1015 | 0.2376 | |
| SRP159526 | C12orf57 | 113246 | RNAseq | 0.3666 | 0.1279 | |
| SRP193095 | C12orf57 | 113246 | RNAseq | 0.0635 | 0.6628 | |
| SRP219564 | C12orf57 | 113246 | RNAseq | 0.0781 | 0.8428 | |
| TCGA | C12orf57 | 113246 | RNAseq | 0.0005 | 0.9934 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by C12orf57 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C12orf57:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C12orf57 | 113246 | 9 | 3 | 18 | |
| GSE20123 | C12orf57 | 113246 | 9 | 3 | 18 | |
| GSE43470 | C12orf57 | 113246 | 8 | 3 | 32 | |
| GSE46452 | C12orf57 | 113246 | 10 | 1 | 48 | |
| GSE47630 | C12orf57 | 113246 | 12 | 2 | 26 | |
| GSE54993 | C12orf57 | 113246 | 1 | 10 | 59 | |
| GSE54994 | C12orf57 | 113246 | 10 | 2 | 41 | |
| GSE60625 | C12orf57 | 113246 | 0 | 1 | 10 | |
| GSE74703 | C12orf57 | 113246 | 7 | 2 | 27 | |
| GSE74704 | C12orf57 | 113246 | 5 | 3 | 12 | |
| TCGA | C12orf57 | 113246 | 40 | 6 | 50 |
Total number of gains: 111; Total number of losses: 36; Total Number of normals: 341.
Somatic mutations of C12orf57:
Generating mutation plots.
Highly correlated genes for C12orf57:
Showing top 20/999 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C12orf57 | C1orf112 | 0.806432 | 3 | 0 | 3 |
| C12orf57 | SNF8 | 0.786123 | 3 | 0 | 3 |
| C12orf57 | AIFM1 | 0.785841 | 3 | 0 | 3 |
| C12orf57 | ZSCAN21 | 0.781759 | 3 | 0 | 3 |
| C12orf57 | ADAR | 0.780432 | 3 | 0 | 3 |
| C12orf57 | FZD6 | 0.777195 | 3 | 0 | 3 |
| C12orf57 | PSMD3 | 0.776854 | 3 | 0 | 3 |
| C12orf57 | NUP107 | 0.773929 | 3 | 0 | 3 |
| C12orf57 | ZBED1 | 0.770395 | 3 | 0 | 3 |
| C12orf57 | SLC38A6 | 0.769723 | 3 | 0 | 3 |
| C12orf57 | ITPR3 | 0.767069 | 3 | 0 | 3 |
| C12orf57 | FHOD3 | 0.76703 | 3 | 0 | 3 |
| C12orf57 | CHST7 | 0.763539 | 3 | 0 | 3 |
| C12orf57 | PTGFRN | 0.760302 | 3 | 0 | 3 |
| C12orf57 | RAD23A | 0.753014 | 3 | 0 | 3 |
| C12orf57 | MSI2 | 0.752568 | 3 | 0 | 3 |
| C12orf57 | ZDHHC4 | 0.750587 | 4 | 0 | 4 |
| C12orf57 | DDX54 | 0.750005 | 3 | 0 | 3 |
| C12orf57 | DDB1 | 0.742502 | 3 | 0 | 3 |
| C12orf57 | COG2 | 0.735864 | 4 | 0 | 4 |
For details and further investigation, click here
