| Full name: Rho GTPase activating protein 19 | Alias Symbol: FLJ00194|MGC14258 | ||
| Type: protein-coding gene | Cytoband: 10q24.1 | ||
| Entrez ID: 84986 | HGNC ID: HGNC:23724 | Ensembl Gene: ENSG00000213390 | OMIM ID: 611587 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ARHGAP19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARHGAP19 | 84986 | 212738_at | 0.5980 | 0.1283 | |
| GSE20347 | ARHGAP19 | 84986 | 212738_at | 0.2917 | 0.0118 | |
| GSE23400 | ARHGAP19 | 84986 | 212738_at | 0.1073 | 0.0007 | |
| GSE26886 | ARHGAP19 | 84986 | 212738_at | -0.1376 | 0.4975 | |
| GSE29001 | ARHGAP19 | 84986 | 212738_at | 0.2486 | 0.2285 | |
| GSE38129 | ARHGAP19 | 84986 | 212738_at | 0.2539 | 0.0209 | |
| GSE45670 | ARHGAP19 | 84986 | 212738_at | -0.0326 | 0.8750 | |
| GSE53622 | ARHGAP19 | 84986 | 26090 | 0.1058 | 0.1636 | |
| GSE53624 | ARHGAP19 | 84986 | 26090 | 0.2980 | 0.0012 | |
| GSE63941 | ARHGAP19 | 84986 | 212738_at | 0.6115 | 0.2306 | |
| GSE77861 | ARHGAP19 | 84986 | 212738_at | 0.0907 | 0.7235 | |
| GSE97050 | ARHGAP19 | 84986 | A_33_P3411025 | 0.2000 | 0.3270 | |
| SRP007169 | ARHGAP19 | 84986 | RNAseq | 1.2188 | 0.0124 | |
| SRP008496 | ARHGAP19 | 84986 | RNAseq | 1.4804 | 0.0001 | |
| SRP064894 | ARHGAP19 | 84986 | RNAseq | 0.1189 | 0.4306 | |
| SRP133303 | ARHGAP19 | 84986 | RNAseq | 0.1409 | 0.4422 | |
| SRP159526 | ARHGAP19 | 84986 | RNAseq | 0.0418 | 0.9186 | |
| SRP193095 | ARHGAP19 | 84986 | RNAseq | 0.0420 | 0.6919 | |
| SRP219564 | ARHGAP19 | 84986 | RNAseq | -0.3182 | 0.3540 | |
| TCGA | ARHGAP19 | 84986 | RNAseq | 0.2106 | 0.0021 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ARHGAP19 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARHGAP19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARHGAP19 | 84986 | 0 | 8 | 22 | |
| GSE20123 | ARHGAP19 | 84986 | 0 | 7 | 23 | |
| GSE43470 | ARHGAP19 | 84986 | 0 | 7 | 36 | |
| GSE46452 | ARHGAP19 | 84986 | 0 | 11 | 48 | |
| GSE47630 | ARHGAP19 | 84986 | 2 | 14 | 24 | |
| GSE54993 | ARHGAP19 | 84986 | 8 | 0 | 62 | |
| GSE54994 | ARHGAP19 | 84986 | 2 | 10 | 41 | |
| GSE60625 | ARHGAP19 | 84986 | 0 | 0 | 11 | |
| GSE74703 | ARHGAP19 | 84986 | 0 | 5 | 31 | |
| GSE74704 | ARHGAP19 | 84986 | 0 | 4 | 16 | |
| TCGA | ARHGAP19 | 84986 | 5 | 28 | 63 |
Total number of gains: 17; Total number of losses: 94; Total Number of normals: 377.
Somatic mutations of ARHGAP19:
Generating mutation plots.
Highly correlated genes for ARHGAP19:
Showing top 20/664 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARHGAP19 | DUS3L | 0.784697 | 3 | 0 | 3 |
| ARHGAP19 | CWF19L2 | 0.775239 | 3 | 0 | 3 |
| ARHGAP19 | BAG6 | 0.767942 | 3 | 0 | 3 |
| ARHGAP19 | DDX10 | 0.76301 | 3 | 0 | 3 |
| ARHGAP19 | SMAD1 | 0.747975 | 3 | 0 | 3 |
| ARHGAP19 | SPSB2 | 0.746706 | 3 | 0 | 3 |
| ARHGAP19 | GLCCI1 | 0.733279 | 3 | 0 | 3 |
| ARHGAP19 | TMEM218 | 0.722792 | 3 | 0 | 3 |
| ARHGAP19 | TIMM9 | 0.720275 | 3 | 0 | 3 |
| ARHGAP19 | MAD2L2 | 0.717275 | 4 | 0 | 4 |
| ARHGAP19 | VCPIP1 | 0.713502 | 3 | 0 | 3 |
| ARHGAP19 | RNF26 | 0.712635 | 3 | 0 | 3 |
| ARHGAP19 | MCPH1 | 0.712474 | 3 | 0 | 3 |
| ARHGAP19 | RBMX | 0.712259 | 3 | 0 | 3 |
| ARHGAP19 | METTL23 | 0.710897 | 5 | 0 | 4 |
| ARHGAP19 | TXLNA | 0.707317 | 3 | 0 | 3 |
| ARHGAP19 | ZFYVE27 | 0.704129 | 4 | 0 | 4 |
| ARHGAP19 | ZNF227 | 0.702815 | 4 | 0 | 4 |
| ARHGAP19 | IFT20 | 0.702673 | 3 | 0 | 3 |
| ARHGAP19 | MRI1 | 0.702251 | 3 | 0 | 3 |
For details and further investigation, click here
