| Full name: transmembrane protein 218 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q24.2 | ||
| Entrez ID: 219854 | HGNC ID: HGNC:27344 | Ensembl Gene: ENSG00000150433 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM218:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM218 | 219854 | 226073_at | -0.1707 | 0.4893 | |
| GSE26886 | TMEM218 | 219854 | 226073_at | -0.6518 | 0.0038 | |
| GSE45670 | TMEM218 | 219854 | 226073_at | 0.0218 | 0.9109 | |
| GSE53622 | TMEM218 | 219854 | 58395 | -0.1192 | 0.1240 | |
| GSE53624 | TMEM218 | 219854 | 58395 | -0.1902 | 0.0787 | |
| GSE63941 | TMEM218 | 219854 | 226073_at | -0.4671 | 0.2644 | |
| GSE77861 | TMEM218 | 219854 | 226073_at | -0.0672 | 0.8117 | |
| GSE97050 | TMEM218 | 219854 | A_23_P1676 | 0.0783 | 0.7484 | |
| SRP007169 | TMEM218 | 219854 | RNAseq | -0.2879 | 0.4965 | |
| SRP008496 | TMEM218 | 219854 | RNAseq | -0.0039 | 0.9895 | |
| SRP064894 | TMEM218 | 219854 | RNAseq | -0.1444 | 0.3704 | |
| SRP133303 | TMEM218 | 219854 | RNAseq | -0.5461 | 0.0001 | |
| SRP159526 | TMEM218 | 219854 | RNAseq | -0.4643 | 0.1272 | |
| SRP193095 | TMEM218 | 219854 | RNAseq | -0.5792 | 0.0000 | |
| SRP219564 | TMEM218 | 219854 | RNAseq | -0.3889 | 0.3681 | |
| TCGA | TMEM218 | 219854 | RNAseq | -0.1203 | 0.1050 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM218 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM218:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM218 | 219854 | 0 | 13 | 17 | |
| GSE20123 | TMEM218 | 219854 | 0 | 13 | 17 | |
| GSE43470 | TMEM218 | 219854 | 2 | 7 | 34 | |
| GSE46452 | TMEM218 | 219854 | 3 | 26 | 30 | |
| GSE47630 | TMEM218 | 219854 | 2 | 19 | 19 | |
| GSE54993 | TMEM218 | 219854 | 10 | 0 | 60 | |
| GSE54994 | TMEM218 | 219854 | 5 | 19 | 29 | |
| GSE60625 | TMEM218 | 219854 | 0 | 3 | 8 | |
| GSE74703 | TMEM218 | 219854 | 1 | 5 | 30 | |
| GSE74704 | TMEM218 | 219854 | 0 | 9 | 11 | |
| TCGA | TMEM218 | 219854 | 6 | 50 | 40 |
Total number of gains: 29; Total number of losses: 164; Total Number of normals: 295.
Somatic mutations of TMEM218:
Generating mutation plots.
Highly correlated genes for TMEM218:
Showing top 20/522 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM218 | AP3M1 | 0.852184 | 3 | 0 | 3 |
| TMEM218 | SP1 | 0.817139 | 3 | 0 | 3 |
| TMEM218 | DUSP16 | 0.794008 | 3 | 0 | 3 |
| TMEM218 | WDR77 | 0.793825 | 3 | 0 | 3 |
| TMEM218 | PRDX3 | 0.790907 | 3 | 0 | 3 |
| TMEM218 | TMEM62 | 0.790703 | 4 | 0 | 4 |
| TMEM218 | PAIP2B | 0.788089 | 3 | 0 | 3 |
| TMEM218 | DCTD | 0.777104 | 4 | 0 | 4 |
| TMEM218 | NR2C1 | 0.77632 | 3 | 0 | 3 |
| TMEM218 | KIAA2026 | 0.774683 | 3 | 0 | 3 |
| TMEM218 | NFXL1 | 0.773709 | 3 | 0 | 3 |
| TMEM218 | NCOR1 | 0.771894 | 4 | 0 | 4 |
| TMEM218 | ACOX1 | 0.769774 | 3 | 0 | 3 |
| TMEM218 | PPM1L | 0.769558 | 3 | 0 | 3 |
| TMEM218 | ZNF416 | 0.769204 | 3 | 0 | 3 |
| TMEM218 | SMARCA2 | 0.768254 | 3 | 0 | 3 |
| TMEM218 | NOTCH2 | 0.766474 | 3 | 0 | 3 |
| TMEM218 | SCOC | 0.766326 | 3 | 0 | 3 |
| TMEM218 | ARIH1 | 0.766115 | 3 | 0 | 3 |
| TMEM218 | CCDC6 | 0.765823 | 3 | 0 | 3 |
For details and further investigation, click here
