| Full name: dihydropyrimidinase like 4 | Alias Symbol: ULIP4|DRP-4 | ||
| Type: protein-coding gene | Cytoband: 10q26.3 | ||
| Entrez ID: 10570 | HGNC ID: HGNC:3016 | Ensembl Gene: ENSG00000151640 | OMIM ID: 608407 |
| Drug and gene relationship at DGIdb | |||
Expression of DPYSL4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DPYSL4 | 10570 | 205492_s_at | -0.0240 | 0.9245 | |
| GSE20347 | DPYSL4 | 10570 | 214301_s_at | -0.0660 | 0.5194 | |
| GSE23400 | DPYSL4 | 10570 | 214301_s_at | -0.2189 | 0.0000 | |
| GSE26886 | DPYSL4 | 10570 | 214301_s_at | 0.0419 | 0.7279 | |
| GSE29001 | DPYSL4 | 10570 | 205492_s_at | -0.0917 | 0.4648 | |
| GSE38129 | DPYSL4 | 10570 | 214301_s_at | -0.1305 | 0.1260 | |
| GSE45670 | DPYSL4 | 10570 | 214301_s_at | 0.0002 | 0.9984 | |
| GSE53622 | DPYSL4 | 10570 | 19925 | -0.0751 | 0.2822 | |
| GSE53624 | DPYSL4 | 10570 | 19925 | 0.0304 | 0.6795 | |
| GSE63941 | DPYSL4 | 10570 | 214301_s_at | 0.0815 | 0.6361 | |
| GSE77861 | DPYSL4 | 10570 | 214301_s_at | -0.0819 | 0.6128 | |
| GSE97050 | DPYSL4 | 10570 | A_33_P3410296 | 0.0283 | 0.9107 | |
| SRP133303 | DPYSL4 | 10570 | RNAseq | 0.7818 | 0.1659 | |
| SRP159526 | DPYSL4 | 10570 | RNAseq | 2.7225 | 0.0017 | |
| SRP219564 | DPYSL4 | 10570 | RNAseq | 0.3732 | 0.6283 | |
| TCGA | DPYSL4 | 10570 | RNAseq | 0.0530 | 0.8932 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DPYSL4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DPYSL4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DPYSL4 | 10570 | 2 | 8 | 20 | |
| GSE20123 | DPYSL4 | 10570 | 2 | 9 | 19 | |
| GSE43470 | DPYSL4 | 10570 | 1 | 9 | 33 | |
| GSE46452 | DPYSL4 | 10570 | 1 | 11 | 47 | |
| GSE47630 | DPYSL4 | 10570 | 4 | 13 | 23 | |
| GSE54993 | DPYSL4 | 10570 | 7 | 1 | 62 | |
| GSE54994 | DPYSL4 | 10570 | 1 | 9 | 43 | |
| GSE60625 | DPYSL4 | 10570 | 0 | 0 | 11 | |
| GSE74703 | DPYSL4 | 10570 | 0 | 6 | 30 | |
| GSE74704 | DPYSL4 | 10570 | 2 | 4 | 14 | |
| TCGA | DPYSL4 | 10570 | 7 | 28 | 61 |
Total number of gains: 27; Total number of losses: 98; Total Number of normals: 363.
Somatic mutations of DPYSL4:
Generating mutation plots.
Highly correlated genes for DPYSL4:
Showing top 20/1086 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DPYSL4 | ARHGAP30 | 0.78938 | 3 | 0 | 3 |
| DPYSL4 | GPHB5 | 0.762858 | 3 | 0 | 3 |
| DPYSL4 | C19orf81 | 0.749088 | 3 | 0 | 3 |
| DPYSL4 | ABCC6 | 0.743975 | 4 | 0 | 4 |
| DPYSL4 | CIB3 | 0.735258 | 3 | 0 | 3 |
| DPYSL4 | ARSA | 0.729529 | 3 | 0 | 3 |
| DPYSL4 | DHH | 0.726511 | 3 | 0 | 3 |
| DPYSL4 | DCAF12L2 | 0.721911 | 3 | 0 | 3 |
| DPYSL4 | CCL26 | 0.720572 | 3 | 0 | 3 |
| DPYSL4 | OPTC | 0.720271 | 3 | 0 | 3 |
| DPYSL4 | KCNT1 | 0.713967 | 4 | 0 | 4 |
| DPYSL4 | SCN1B | 0.713319 | 4 | 0 | 4 |
| DPYSL4 | HAAO | 0.711959 | 7 | 0 | 6 |
| DPYSL4 | ABCA4 | 0.710993 | 4 | 0 | 4 |
| DPYSL4 | CALML6 | 0.708208 | 3 | 0 | 3 |
| DPYSL4 | SP8 | 0.707907 | 3 | 0 | 3 |
| DPYSL4 | RASL10A | 0.707591 | 5 | 0 | 4 |
| DPYSL4 | RNF123 | 0.707484 | 4 | 0 | 4 |
| DPYSL4 | GALNT8 | 0.706026 | 5 | 0 | 5 |
| DPYSL4 | RGL4 | 0.704814 | 4 | 0 | 3 |
For details and further investigation, click here
