| Full name: claudin 19 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p34.2 | ||
| Entrez ID: 149461 | HGNC ID: HGNC:2040 | Ensembl Gene: ENSG00000164007 | OMIM ID: 610036 |
| Drug and gene relationship at DGIdb | |||
CLDN19 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04530 | Tight junction |
Expression of CLDN19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CLDN19 | 149461 | 1554804_a_at | -0.0420 | 0.9035 | |
| GSE26886 | CLDN19 | 149461 | 1554804_a_at | 0.4646 | 0.1435 | |
| GSE45670 | CLDN19 | 149461 | 1554804_a_at | -0.0262 | 0.7492 | |
| GSE53622 | CLDN19 | 149461 | 88268 | -0.2896 | 0.0026 | |
| GSE53624 | CLDN19 | 149461 | 88268 | -0.4451 | 0.0000 | |
| GSE63941 | CLDN19 | 149461 | 1554804_a_at | 0.5942 | 0.0044 | |
| GSE77861 | CLDN19 | 149461 | 1554804_a_at | 0.0312 | 0.7861 | |
| GSE97050 | CLDN19 | 149461 | A_33_P3299739 | -0.1577 | 0.5161 | |
| SRP133303 | CLDN19 | 149461 | RNAseq | 0.7705 | 0.1754 | |
| TCGA | CLDN19 | 149461 | RNAseq | -0.4248 | 0.6069 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CLDN19 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CLDN19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLDN19 | 149461 | 4 | 3 | 23 | |
| GSE20123 | CLDN19 | 149461 | 3 | 2 | 25 | |
| GSE43470 | CLDN19 | 149461 | 7 | 2 | 34 | |
| GSE46452 | CLDN19 | 149461 | 3 | 1 | 55 | |
| GSE47630 | CLDN19 | 149461 | 9 | 2 | 29 | |
| GSE54993 | CLDN19 | 149461 | 0 | 2 | 68 | |
| GSE54994 | CLDN19 | 149461 | 14 | 2 | 37 | |
| GSE60625 | CLDN19 | 149461 | 0 | 0 | 11 | |
| GSE74703 | CLDN19 | 149461 | 6 | 1 | 29 | |
| GSE74704 | CLDN19 | 149461 | 1 | 0 | 19 | |
| TCGA | CLDN19 | 149461 | 13 | 16 | 67 |
Total number of gains: 60; Total number of losses: 31; Total Number of normals: 397.
Somatic mutations of CLDN19:
Generating mutation plots.
Highly correlated genes for CLDN19:
Showing top 20/297 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLDN19 | C12orf40 | 0.751736 | 3 | 0 | 3 |
| CLDN19 | TMEM151A | 0.74754 | 4 | 0 | 4 |
| CLDN19 | AGXT | 0.747242 | 3 | 0 | 3 |
| CLDN19 | ARHGAP33 | 0.741276 | 3 | 0 | 3 |
| CLDN19 | MARK4 | 0.731986 | 3 | 0 | 3 |
| CLDN19 | RIBC1 | 0.708579 | 3 | 0 | 3 |
| CLDN19 | TTC34 | 0.696839 | 3 | 0 | 3 |
| CLDN19 | KRTAP9-1 | 0.694507 | 3 | 0 | 3 |
| CLDN19 | KCNH3 | 0.693052 | 4 | 0 | 4 |
| CLDN19 | IFNL2 | 0.691818 | 4 | 0 | 4 |
| CLDN19 | RPH3A | 0.690949 | 3 | 0 | 3 |
| CLDN19 | ELFN1-AS1 | 0.689604 | 3 | 0 | 3 |
| CLDN19 | HMX1 | 0.689159 | 6 | 0 | 5 |
| CLDN19 | CNOT3 | 0.682689 | 3 | 0 | 3 |
| CLDN19 | CCL16 | 0.681009 | 4 | 0 | 3 |
| CLDN19 | CCDC169 | 0.680408 | 3 | 0 | 3 |
| CLDN19 | ENTPD2 | 0.673039 | 4 | 0 | 4 |
| CLDN19 | CCDC78 | 0.671422 | 5 | 0 | 5 |
| CLDN19 | MAPK4 | 0.667207 | 4 | 0 | 3 |
| CLDN19 | KRTAP4-8 | 0.66383 | 3 | 0 | 3 |
For details and further investigation, click here
