| Full name: coiled-coil domain containing 78 | Alias Symbol: FLJ34512 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 124093 | HGNC ID: HGNC:14153 | Ensembl Gene: ENSG00000162004 | OMIM ID: 614666 |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC78:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC78 | 124093 | 236745_at | 0.1803 | 0.4794 | |
| GSE26886 | CCDC78 | 124093 | 236745_at | 0.0642 | 0.4711 | |
| GSE45670 | CCDC78 | 124093 | 236745_at | 0.0880 | 0.2912 | |
| GSE53622 | CCDC78 | 124093 | 119551 | -0.4744 | 0.0000 | |
| GSE53624 | CCDC78 | 124093 | 119551 | -0.3454 | 0.0000 | |
| GSE63941 | CCDC78 | 124093 | 236745_at | 0.1254 | 0.4443 | |
| GSE77861 | CCDC78 | 124093 | 236745_at | 0.1096 | 0.3972 | |
| GSE97050 | CCDC78 | 124093 | A_33_P3246613 | -0.4153 | 0.2164 | |
| SRP133303 | CCDC78 | 124093 | RNAseq | 0.6000 | 0.0567 | |
| SRP159526 | CCDC78 | 124093 | RNAseq | 0.8781 | 0.0969 | |
| SRP193095 | CCDC78 | 124093 | RNAseq | 0.8794 | 0.0000 | |
| SRP219564 | CCDC78 | 124093 | RNAseq | 1.8003 | 0.0095 | |
| TCGA | CCDC78 | 124093 | RNAseq | 0.6118 | 0.0290 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CCDC78 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC78:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC78 | 124093 | 5 | 5 | 20 | |
| GSE20123 | CCDC78 | 124093 | 5 | 4 | 21 | |
| GSE43470 | CCDC78 | 124093 | 4 | 7 | 32 | |
| GSE46452 | CCDC78 | 124093 | 38 | 1 | 20 | |
| GSE47630 | CCDC78 | 124093 | 13 | 6 | 21 | |
| GSE54993 | CCDC78 | 124093 | 3 | 5 | 62 | |
| GSE54994 | CCDC78 | 124093 | 5 | 9 | 39 | |
| GSE60625 | CCDC78 | 124093 | 4 | 0 | 7 | |
| GSE74703 | CCDC78 | 124093 | 4 | 5 | 27 | |
| GSE74704 | CCDC78 | 124093 | 3 | 2 | 15 | |
| TCGA | CCDC78 | 124093 | 20 | 15 | 61 |
Total number of gains: 104; Total number of losses: 59; Total Number of normals: 325.
Somatic mutations of CCDC78:
Generating mutation plots.
Highly correlated genes for CCDC78:
Showing top 20/149 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC78 | GPSM1 | 0.715416 | 4 | 0 | 3 |
| CCDC78 | SFTPA2 | 0.712927 | 3 | 0 | 3 |
| CCDC78 | ATRNL1 | 0.704484 | 4 | 0 | 4 |
| CCDC78 | BET1L | 0.702557 | 3 | 0 | 3 |
| CCDC78 | ZBTB4 | 0.699534 | 3 | 0 | 3 |
| CCDC78 | IL3RA | 0.696153 | 4 | 0 | 3 |
| CCDC78 | SIX5 | 0.693707 | 3 | 0 | 3 |
| CCDC78 | REEP2 | 0.693673 | 3 | 0 | 3 |
| CCDC78 | ARHGAP33 | 0.687192 | 3 | 0 | 3 |
| CCDC78 | ZBTB16 | 0.684348 | 3 | 0 | 3 |
| CCDC78 | CLDN19 | 0.671422 | 5 | 0 | 5 |
| CCDC78 | SPSB4 | 0.667981 | 6 | 0 | 5 |
| CCDC78 | RAB3A | 0.657177 | 3 | 0 | 3 |
| CCDC78 | MXRA7 | 0.655196 | 3 | 0 | 3 |
| CCDC78 | DNAAF2 | 0.65418 | 3 | 0 | 3 |
| CCDC78 | CCDC40 | 0.653878 | 3 | 0 | 3 |
| CCDC78 | ATF5 | 0.649262 | 3 | 0 | 3 |
| CCDC78 | TCAP | 0.647967 | 4 | 0 | 3 |
| CCDC78 | IGSF1 | 0.642753 | 3 | 0 | 3 |
| CCDC78 | SFXN5 | 0.641207 | 5 | 0 | 4 |
For details and further investigation, click here
