| Full name: IQ motif and Sec7 domain 2 | Alias Symbol: KIAA0522|BRAG1|IQ-ArfGEF | ||
| Type: protein-coding gene | Cytoband: Xp11.22 | ||
| Entrez ID: 23096 | HGNC ID: HGNC:29059 | Ensembl Gene: ENSG00000124313 | OMIM ID: 300522 |
| Drug and gene relationship at DGIdb | |||
Expression of IQSEC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IQSEC2 | 23096 | 229840_at | -0.0171 | 0.9599 | |
| GSE20347 | IQSEC2 | 23096 | 214819_at | -0.0510 | 0.5409 | |
| GSE23400 | IQSEC2 | 23096 | 214819_at | -0.1241 | 0.0023 | |
| GSE26886 | IQSEC2 | 23096 | 214819_at | 0.5277 | 0.0006 | |
| GSE29001 | IQSEC2 | 23096 | 214819_at | -0.2056 | 0.2653 | |
| GSE38129 | IQSEC2 | 23096 | 214819_at | -0.1182 | 0.1074 | |
| GSE45670 | IQSEC2 | 23096 | 214819_at | 0.0445 | 0.6196 | |
| GSE53622 | IQSEC2 | 23096 | 51969 | -0.0050 | 0.9381 | |
| GSE53624 | IQSEC2 | 23096 | 51969 | -0.1235 | 0.0791 | |
| GSE63941 | IQSEC2 | 23096 | 229840_at | 0.0855 | 0.7835 | |
| GSE77861 | IQSEC2 | 23096 | 229840_at | -0.2930 | 0.0278 | |
| GSE97050 | IQSEC2 | 23096 | A_32_P159445 | -0.0169 | 0.9461 | |
| SRP007169 | IQSEC2 | 23096 | RNAseq | -0.3499 | 0.4516 | |
| SRP008496 | IQSEC2 | 23096 | RNAseq | 0.3855 | 0.3547 | |
| SRP064894 | IQSEC2 | 23096 | RNAseq | 0.1477 | 0.6327 | |
| SRP133303 | IQSEC2 | 23096 | RNAseq | -0.0471 | 0.8671 | |
| SRP159526 | IQSEC2 | 23096 | RNAseq | -0.0090 | 0.9700 | |
| SRP193095 | IQSEC2 | 23096 | RNAseq | -0.0315 | 0.7692 | |
| SRP219564 | IQSEC2 | 23096 | RNAseq | -0.2666 | 0.4062 | |
| TCGA | IQSEC2 | 23096 | RNAseq | -0.1124 | 0.0749 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IQSEC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IQSEC2:
No record found for this gene.
Somatic mutations of IQSEC2:
Generating mutation plots.
Highly correlated genes for IQSEC2:
Showing top 20/584 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IQSEC2 | TTC9B | 0.741544 | 3 | 0 | 3 |
| IQSEC2 | GLI1 | 0.731802 | 3 | 0 | 3 |
| IQSEC2 | LRP3 | 0.700102 | 3 | 0 | 3 |
| IQSEC2 | PRR7-AS1 | 0.699787 | 3 | 0 | 3 |
| IQSEC2 | NLGN4X | 0.698635 | 3 | 0 | 3 |
| IQSEC2 | C9orf131 | 0.69584 | 3 | 0 | 3 |
| IQSEC2 | ARHGAP33 | 0.693333 | 5 | 0 | 4 |
| IQSEC2 | MCEMP1 | 0.6857 | 3 | 0 | 3 |
| IQSEC2 | RCE1 | 0.685333 | 3 | 0 | 3 |
| IQSEC2 | KDM6B | 0.684959 | 3 | 0 | 3 |
| IQSEC2 | ARR3 | 0.684302 | 3 | 0 | 3 |
| IQSEC2 | PRKACG | 0.682782 | 5 | 0 | 5 |
| IQSEC2 | NOX5 | 0.68213 | 4 | 0 | 4 |
| IQSEC2 | HMCN2 | 0.679004 | 4 | 0 | 3 |
| IQSEC2 | ARX | 0.676587 | 3 | 0 | 3 |
| IQSEC2 | SSUH2 | 0.67602 | 4 | 0 | 3 |
| IQSEC2 | FGF21 | 0.670575 | 6 | 0 | 6 |
| IQSEC2 | PNPLA7 | 0.668178 | 4 | 0 | 3 |
| IQSEC2 | ETV2 | 0.666767 | 6 | 0 | 6 |
| IQSEC2 | DOC2B | 0.663776 | 7 | 0 | 6 |
For details and further investigation, click here
