| Full name: nuclear factor I X | Alias Symbol: NF1A | ||
| Type: protein-coding gene | Cytoband: 19p13.13 | ||
| Entrez ID: 4784 | HGNC ID: HGNC:7788 | Ensembl Gene: ENSG00000008441 | OMIM ID: 164005 |
| Drug and gene relationship at DGIdb | |||
Expression of NFIX:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NFIX | 4784 | 227400_at | -0.9105 | 0.1775 | |
| GSE20347 | NFIX | 4784 | 209807_s_at | -0.0984 | 0.1906 | |
| GSE23400 | NFIX | 4784 | 209807_s_at | -0.1555 | 0.0000 | |
| GSE26886 | NFIX | 4784 | 227400_at | -0.1562 | 0.3720 | |
| GSE29001 | NFIX | 4784 | 209807_s_at | 0.0409 | 0.7703 | |
| GSE38129 | NFIX | 4784 | 209807_s_at | -0.2794 | 0.0791 | |
| GSE45670 | NFIX | 4784 | 227400_at | -1.1256 | 0.0000 | |
| GSE53622 | NFIX | 4784 | 56268 | -1.4267 | 0.0000 | |
| GSE53624 | NFIX | 4784 | 56268 | -1.3985 | 0.0000 | |
| GSE63941 | NFIX | 4784 | 228278_at | -1.4837 | 0.0003 | |
| GSE77861 | NFIX | 4784 | 227400_at | -0.8126 | 0.0047 | |
| GSE97050 | NFIX | 4784 | A_33_P3884230 | -0.6581 | 0.2198 | |
| SRP007169 | NFIX | 4784 | RNAseq | -1.6440 | 0.0002 | |
| SRP008496 | NFIX | 4784 | RNAseq | -1.5975 | 0.0000 | |
| SRP064894 | NFIX | 4784 | RNAseq | -0.9494 | 0.0003 | |
| SRP133303 | NFIX | 4784 | RNAseq | -1.7931 | 0.0000 | |
| SRP159526 | NFIX | 4784 | RNAseq | -0.6333 | 0.1946 | |
| SRP193095 | NFIX | 4784 | RNAseq | -0.9528 | 0.0000 | |
| SRP219564 | NFIX | 4784 | RNAseq | -0.6848 | 0.2097 | |
| TCGA | NFIX | 4784 | RNAseq | -0.2888 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by NFIX expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NFIX:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NFIX | 4784 | 4 | 2 | 24 | |
| GSE20123 | NFIX | 4784 | 3 | 1 | 26 | |
| GSE43470 | NFIX | 4784 | 2 | 6 | 35 | |
| GSE46452 | NFIX | 4784 | 47 | 1 | 11 | |
| GSE47630 | NFIX | 4784 | 4 | 7 | 29 | |
| GSE54993 | NFIX | 4784 | 16 | 3 | 51 | |
| GSE54994 | NFIX | 4784 | 6 | 13 | 34 | |
| GSE60625 | NFIX | 4784 | 9 | 0 | 2 | |
| GSE74703 | NFIX | 4784 | 2 | 4 | 30 | |
| GSE74704 | NFIX | 4784 | 0 | 1 | 19 | |
| TCGA | NFIX | 4784 | 18 | 13 | 65 |
Total number of gains: 111; Total number of losses: 51; Total Number of normals: 326.
Somatic mutations of NFIX:
Generating mutation plots.
Highly correlated genes for NFIX:
Showing top 20/1344 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NFIX | NFIA | 0.836908 | 6 | 0 | 6 |
| NFIX | CYP21A2 | 0.82733 | 3 | 0 | 3 |
| NFIX | BOC | 0.808247 | 7 | 0 | 7 |
| NFIX | CLEC3B | 0.799689 | 3 | 0 | 3 |
| NFIX | EIF4E3 | 0.778411 | 6 | 0 | 6 |
| NFIX | ANGPTL1 | 0.766683 | 6 | 0 | 6 |
| NFIX | METTL7A | 0.765431 | 7 | 0 | 7 |
| NFIX | GALNT12 | 0.764011 | 5 | 0 | 5 |
| NFIX | MRAS | 0.764006 | 3 | 0 | 3 |
| NFIX | RCAN2 | 0.760675 | 7 | 0 | 7 |
| NFIX | CXCL12 | 0.760113 | 7 | 0 | 7 |
| NFIX | RBFOX3 | 0.754997 | 3 | 0 | 3 |
| NFIX | GPRASP2 | 0.752728 | 3 | 0 | 3 |
| NFIX | CASQ2 | 0.751275 | 6 | 0 | 6 |
| NFIX | OXR1 | 0.750494 | 6 | 0 | 6 |
| NFIX | LINC01315 | 0.749339 | 5 | 0 | 5 |
| NFIX | TNS1 | 0.745368 | 8 | 0 | 8 |
| NFIX | ASPA | 0.744831 | 8 | 0 | 8 |
| NFIX | GFRA1 | 0.744455 | 6 | 0 | 6 |
| NFIX | SVIP | 0.744181 | 6 | 0 | 6 |
For details and further investigation, click here
