| Full name: arrestin domain containing 2 | Alias Symbol: CLONE24945|PP2703 | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 27106 | HGNC ID: HGNC:25225 | Ensembl Gene: ENSG00000105643 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ARRDC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARRDC2 | 27106 | 226055_at | -0.0342 | 0.9651 | |
| GSE26886 | ARRDC2 | 27106 | 226055_at | 0.5759 | 0.0324 | |
| GSE45670 | ARRDC2 | 27106 | 226055_at | -0.0259 | 0.8872 | |
| GSE53622 | ARRDC2 | 27106 | 2985 | -0.2514 | 0.0002 | |
| GSE53624 | ARRDC2 | 27106 | 2985 | -0.4170 | 0.0000 | |
| GSE63941 | ARRDC2 | 27106 | 226055_at | 0.1887 | 0.4881 | |
| GSE77861 | ARRDC2 | 27106 | 226055_at | 0.2553 | 0.0221 | |
| GSE97050 | ARRDC2 | 27106 | A_24_P22976 | 0.0351 | 0.9385 | |
| SRP007169 | ARRDC2 | 27106 | RNAseq | -0.9514 | 0.0737 | |
| SRP008496 | ARRDC2 | 27106 | RNAseq | -0.7305 | 0.0337 | |
| SRP064894 | ARRDC2 | 27106 | RNAseq | -0.0235 | 0.9170 | |
| SRP133303 | ARRDC2 | 27106 | RNAseq | -0.4580 | 0.0439 | |
| SRP159526 | ARRDC2 | 27106 | RNAseq | -0.7470 | 0.0511 | |
| SRP193095 | ARRDC2 | 27106 | RNAseq | -0.1955 | 0.2689 | |
| SRP219564 | ARRDC2 | 27106 | RNAseq | 0.4690 | 0.3343 | |
| TCGA | ARRDC2 | 27106 | RNAseq | -0.2288 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ARRDC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARRDC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARRDC2 | 27106 | 4 | 4 | 22 | |
| GSE20123 | ARRDC2 | 27106 | 3 | 2 | 25 | |
| GSE43470 | ARRDC2 | 27106 | 2 | 6 | 35 | |
| GSE46452 | ARRDC2 | 27106 | 47 | 1 | 11 | |
| GSE47630 | ARRDC2 | 27106 | 4 | 8 | 28 | |
| GSE54993 | ARRDC2 | 27106 | 15 | 4 | 51 | |
| GSE54994 | ARRDC2 | 27106 | 6 | 14 | 33 | |
| GSE60625 | ARRDC2 | 27106 | 9 | 0 | 2 | |
| GSE74703 | ARRDC2 | 27106 | 2 | 4 | 30 | |
| GSE74704 | ARRDC2 | 27106 | 0 | 2 | 18 | |
| TCGA | ARRDC2 | 27106 | 17 | 9 | 70 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of ARRDC2:
Generating mutation plots.
Highly correlated genes for ARRDC2:
Showing top 20/37 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARRDC2 | LONP1 | 0.695151 | 3 | 0 | 3 |
| ARRDC2 | ATF7IP2 | 0.65716 | 3 | 0 | 3 |
| ARRDC2 | RPP25 | 0.649261 | 3 | 0 | 3 |
| ARRDC2 | ZRSR2 | 0.644371 | 3 | 0 | 3 |
| ARRDC2 | DHX9 | 0.624149 | 3 | 0 | 3 |
| ARRDC2 | ARL8A | 0.611274 | 3 | 0 | 3 |
| ARRDC2 | SLC12A7 | 0.609587 | 3 | 0 | 3 |
| ARRDC2 | ASMTL | 0.607508 | 4 | 0 | 3 |
| ARRDC2 | ENKD1 | 0.607396 | 3 | 0 | 3 |
| ARRDC2 | IRAK1 | 0.603818 | 3 | 0 | 3 |
| ARRDC2 | ASCL2 | 0.602397 | 4 | 0 | 3 |
| ARRDC2 | SLC2A11 | 0.598504 | 3 | 0 | 3 |
| ARRDC2 | KCNN4 | 0.5983 | 4 | 0 | 3 |
| ARRDC2 | TRIM11 | 0.591836 | 4 | 0 | 3 |
| ARRDC2 | WRNIP1 | 0.591381 | 3 | 0 | 3 |
| ARRDC2 | FAM210B | 0.586983 | 3 | 0 | 3 |
| ARRDC2 | CPAMD8 | 0.575731 | 4 | 0 | 3 |
| ARRDC2 | NTHL1 | 0.570654 | 3 | 0 | 3 |
| ARRDC2 | TIGD7 | 0.569405 | 4 | 0 | 4 |
| ARRDC2 | DNLZ | 0.56932 | 4 | 0 | 3 |
For details and further investigation, click here
