DNLZ

 

Full name: DNL-type zinc finger Alias Symbol: RP11-413M3.2|ZIM17|bA413M3.2|TIMM15|HEP
Type: protein-coding gene Cytoband: 9q34.3
Entrez ID: 728489 HGNC ID: HGNC:33879 Ensembl Gene: ENSG00000213221 OMIM ID: 
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of DNLZ:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DNLZ 728489 228272_at 0.6588 0.3019
GSE26886 DNLZ 728489 228272_at 1.6737 0.0000
GSE45670 DNLZ 728489 228272_at 0.6071 0.0698
GSE53622 DNLZ 728489 14277 -0.0113 0.8927
GSE53624 DNLZ 728489 14277 0.1648 0.0085
GSE63941 DNLZ 728489 228272_at -0.4015 0.6301
GSE77861 DNLZ 728489 228272_at 0.5478 0.1593
GSE97050 DNLZ 728489 A_33_P3358403 0.0751 0.7541
SRP007169 DNLZ 728489 RNAseq 0.4274 0.5129
SRP064894 DNLZ 728489 RNAseq 1.7083 0.0004
SRP133303 DNLZ 728489 RNAseq 0.5747 0.1108
SRP159526 DNLZ 728489 RNAseq 1.1889 0.0001
SRP193095 DNLZ 728489 RNAseq 0.7174 0.0004
SRP219564 DNLZ 728489 RNAseq 0.8775 0.0538
TCGA DNLZ 728489 RNAseq 0.3823 0.0004

Upregulated datasets: 3; Downregulated datasets: 0.  


 

Survival by DNLZ expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of DNLZ:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DNLZ 728489 4 7 19
GSE20123 DNLZ 728489 4 7 19
GSE43470 DNLZ 728489 3 7 33
GSE46452 DNLZ 728489 6 13 40
GSE47630 DNLZ 728489 6 15 19
GSE54993 DNLZ 728489 3 3 64
GSE54994 DNLZ 728489 13 7 33
GSE60625 DNLZ 728489 0 0 11
GSE74703 DNLZ 728489 3 5 28
GSE74704 DNLZ 728489 2 5 13
TCGA DNLZ 728489 29 24 43

Total number of gains: 73; Total number of losses: 93; Total Number of normals: 322.  


 

Somatic mutations of DNLZ:

 

Generating mutation plots.

 

Highly correlated genes for DNLZ:

 

Showing top 20/178 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DNLZSTK32C0.821025303
DNLZFBXO440.801046303
DNLZZMYND150.79403303
DNLZDOHH0.782083303
DNLZCPAMD80.748366404
DNLZIL15RA0.742524303
DNLZAMPD20.740392303
DNLZTIGD50.734404303
DNLZGNL10.721163303
DNLZHGD0.719107303
DNLZSIRT50.716856404
DNLZTNIP20.714865303
DNLZZNF2320.700909303
DNLZTRMT10C0.699738303
DNLZLINC010100.697711303
DNLZSCN9A0.693155303
DNLZSMC1B0.691719303
DNLZPHF10.689795303
DNLZEYS0.685616303
DNLZC11orf950.685398303

For details and further investigation, click here