| Full name: ADP ribosylation factor like GTPase 8A | Alias Symbol: FLJ45195|Gie2 | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 127829 | HGNC ID: HGNC:25192 | Ensembl Gene: ENSG00000143862 | OMIM ID: 616597 |
| Drug and gene relationship at DGIdb | |||
Expression of ARL8A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARL8A | 127829 | 225347_at | 0.1418 | 0.6725 | |
| GSE26886 | ARL8A | 127829 | 225347_at | 0.0227 | 0.8872 | |
| GSE45670 | ARL8A | 127829 | 225347_at | 0.0201 | 0.8642 | |
| GSE53622 | ARL8A | 127829 | 107400 | 0.1032 | 0.0134 | |
| GSE53624 | ARL8A | 127829 | 107400 | 0.0720 | 0.1075 | |
| GSE63941 | ARL8A | 127829 | 225347_at | -0.0579 | 0.8800 | |
| GSE77861 | ARL8A | 127829 | 225347_at | 0.2231 | 0.2992 | |
| GSE97050 | ARL8A | 127829 | A_23_P138271 | -0.0552 | 0.8039 | |
| SRP007169 | ARL8A | 127829 | RNAseq | -0.8466 | 0.0252 | |
| SRP008496 | ARL8A | 127829 | RNAseq | -0.4735 | 0.0705 | |
| SRP064894 | ARL8A | 127829 | RNAseq | 0.2041 | 0.1983 | |
| SRP133303 | ARL8A | 127829 | RNAseq | 0.2627 | 0.0337 | |
| SRP159526 | ARL8A | 127829 | RNAseq | 0.2160 | 0.3720 | |
| SRP193095 | ARL8A | 127829 | RNAseq | 0.2656 | 0.0272 | |
| SRP219564 | ARL8A | 127829 | RNAseq | 0.0352 | 0.8883 | |
| TCGA | ARL8A | 127829 | RNAseq | 0.0422 | 0.3897 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ARL8A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARL8A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARL8A | 127829 | 11 | 0 | 19 | |
| GSE20123 | ARL8A | 127829 | 11 | 0 | 19 | |
| GSE43470 | ARL8A | 127829 | 6 | 0 | 37 | |
| GSE46452 | ARL8A | 127829 | 3 | 1 | 55 | |
| GSE47630 | ARL8A | 127829 | 14 | 0 | 26 | |
| GSE54993 | ARL8A | 127829 | 0 | 6 | 64 | |
| GSE54994 | ARL8A | 127829 | 15 | 0 | 38 | |
| GSE60625 | ARL8A | 127829 | 0 | 0 | 11 | |
| GSE74703 | ARL8A | 127829 | 6 | 0 | 30 | |
| GSE74704 | ARL8A | 127829 | 5 | 0 | 15 | |
| TCGA | ARL8A | 127829 | 43 | 4 | 49 |
Total number of gains: 114; Total number of losses: 11; Total Number of normals: 363.
Somatic mutations of ARL8A:
Generating mutation plots.
Highly correlated genes for ARL8A:
Showing top 20/77 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARL8A | SYCE1L | 0.809909 | 3 | 0 | 3 |
| ARL8A | HCN3 | 0.801726 | 3 | 0 | 3 |
| ARL8A | CUL9 | 0.780793 | 3 | 0 | 3 |
| ARL8A | FBRSL1 | 0.764058 | 3 | 0 | 3 |
| ARL8A | CADM4 | 0.763291 | 3 | 0 | 3 |
| ARL8A | PMPCA | 0.750083 | 3 | 0 | 3 |
| ARL8A | TIGD5 | 0.741719 | 3 | 0 | 3 |
| ARL8A | SOX30 | 0.739798 | 3 | 0 | 3 |
| ARL8A | ACVR2B | 0.739156 | 3 | 0 | 3 |
| ARL8A | GSDMD | 0.737778 | 3 | 0 | 3 |
| ARL8A | E2F1 | 0.729959 | 3 | 0 | 3 |
| ARL8A | PRPF3 | 0.726995 | 3 | 0 | 3 |
| ARL8A | ZBTB48 | 0.724671 | 4 | 0 | 4 |
| ARL8A | GTF2IRD2 | 0.72077 | 3 | 0 | 3 |
| ARL8A | CNOT3 | 0.715981 | 3 | 0 | 3 |
| ARL8A | SYPL2 | 0.714646 | 3 | 0 | 3 |
| ARL8A | BCAP31 | 0.711444 | 3 | 0 | 3 |
| ARL8A | CELSR3 | 0.708032 | 3 | 0 | 3 |
| ARL8A | BAZ2A | 0.699331 | 3 | 0 | 3 |
| ARL8A | PHF1 | 0.699327 | 4 | 0 | 3 |
For details and further investigation, click here
