| Full name: ribonuclease P and MRP subunit p25 | Alias Symbol: FLJ20374 | ||
| Type: protein-coding gene | Cytoband: 15q24.2 | ||
| Entrez ID: 54913 | HGNC ID: HGNC:30361 | Ensembl Gene: ENSG00000178718 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of RPP25:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPP25 | 54913 | 219143_s_at | 0.9544 | 0.0674 | |
| GSE20347 | RPP25 | 54913 | 219143_s_at | 0.9925 | 0.0000 | |
| GSE23400 | RPP25 | 54913 | 219143_s_at | 0.6578 | 0.0000 | |
| GSE26886 | RPP25 | 54913 | 223415_at | 0.9610 | 0.0000 | |
| GSE29001 | RPP25 | 54913 | 219143_s_at | 0.5832 | 0.0008 | |
| GSE38129 | RPP25 | 54913 | 219143_s_at | 1.2797 | 0.0000 | |
| GSE45670 | RPP25 | 54913 | 219143_s_at | 0.5628 | 0.0109 | |
| GSE53622 | RPP25 | 54913 | 75349 | 0.4997 | 0.0000 | |
| GSE53624 | RPP25 | 54913 | 75349 | 0.5606 | 0.0000 | |
| GSE63941 | RPP25 | 54913 | 219143_s_at | 1.8147 | 0.0983 | |
| GSE77861 | RPP25 | 54913 | 223415_at | 0.2177 | 0.3338 | |
| GSE97050 | RPP25 | 54913 | A_33_P3271316 | 0.1035 | 0.6130 | |
| SRP007169 | RPP25 | 54913 | RNAseq | 0.5257 | 0.3143 | |
| SRP064894 | RPP25 | 54913 | RNAseq | 1.4285 | 0.0000 | |
| SRP133303 | RPP25 | 54913 | RNAseq | 1.2744 | 0.0001 | |
| SRP159526 | RPP25 | 54913 | RNAseq | 1.4381 | 0.0000 | |
| SRP193095 | RPP25 | 54913 | RNAseq | 0.9221 | 0.0000 | |
| SRP219564 | RPP25 | 54913 | RNAseq | 0.5301 | 0.2794 | |
| TCGA | RPP25 | 54913 | RNAseq | 0.2891 | 0.0051 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by RPP25 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPP25:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPP25 | 54913 | 8 | 1 | 21 | |
| GSE20123 | RPP25 | 54913 | 8 | 1 | 21 | |
| GSE43470 | RPP25 | 54913 | 4 | 6 | 33 | |
| GSE46452 | RPP25 | 54913 | 3 | 7 | 49 | |
| GSE47630 | RPP25 | 54913 | 8 | 10 | 22 | |
| GSE54993 | RPP25 | 54913 | 5 | 6 | 59 | |
| GSE54994 | RPP25 | 54913 | 5 | 7 | 41 | |
| GSE60625 | RPP25 | 54913 | 4 | 0 | 7 | |
| GSE74703 | RPP25 | 54913 | 4 | 3 | 29 | |
| GSE74704 | RPP25 | 54913 | 4 | 1 | 15 | |
| TCGA | RPP25 | 54913 | 14 | 15 | 67 |
Total number of gains: 67; Total number of losses: 57; Total Number of normals: 364.
Somatic mutations of RPP25:
Generating mutation plots.
Highly correlated genes for RPP25:
Showing top 20/557 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPP25 | MGAT5B | 0.801911 | 3 | 0 | 3 |
| RPP25 | MIIP | 0.794226 | 5 | 0 | 5 |
| RPP25 | LRFN3 | 0.770184 | 3 | 0 | 3 |
| RPP25 | UMODL1 | 0.759696 | 3 | 0 | 3 |
| RPP25 | SCUBE1 | 0.756794 | 3 | 0 | 3 |
| RPP25 | ADRA2C | 0.746261 | 3 | 0 | 3 |
| RPP25 | CDH4 | 0.74544 | 3 | 0 | 3 |
| RPP25 | STK32C | 0.73301 | 4 | 0 | 4 |
| RPP25 | ABCC6 | 0.726322 | 3 | 0 | 3 |
| RPP25 | FXYD4 | 0.726097 | 3 | 0 | 3 |
| RPP25 | AGAP2 | 0.725913 | 3 | 0 | 3 |
| RPP25 | NKAIN4 | 0.721555 | 3 | 0 | 3 |
| RPP25 | SP8 | 0.720674 | 3 | 0 | 3 |
| RPP25 | C20orf141 | 0.719992 | 3 | 0 | 3 |
| RPP25 | ZNF48 | 0.714776 | 3 | 0 | 3 |
| RPP25 | POC1A | 0.713458 | 5 | 0 | 5 |
| RPP25 | DNAJB8 | 0.711445 | 3 | 0 | 3 |
| RPP25 | RASGEF1A | 0.71088 | 3 | 0 | 3 |
| RPP25 | PELI3 | 0.709936 | 3 | 0 | 3 |
| RPP25 | ARVCF | 0.704246 | 4 | 0 | 3 |
For details and further investigation, click here
