IRAK1

 

Full name: interleukin 1 receptor associated kinase 1 Alias Symbol: IRAK|pelle
Type: protein-coding gene Cytoband: Xq28
Entrez ID: 3654 HGNC ID: HGNC:6112 Ensembl Gene: ENSG00000184216 OMIM ID: 300283
Related drugs: CHEMBL379787... [more]

 

IRAK1 involved pathways:

KEGG pathway Description View
hsa04064NF-kappa B signaling pathway
hsa04620Toll-like receptor signaling pathway
hsa04722Neurotrophin signaling pathway
hsa05133Pertussis
hsa05140Leishmaniasis
hsa05142Chagas disease (American trypanosomiasis)
hsa05145Toxoplasmosis
hsa05152Tuberculosis
hsa05162Measles
hsa05169Epstein-Barr virus infection

 

Expression of IRAK1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 IRAK1 3654 201587_s_at 0.4302 0.4335
GSE20347 IRAK1 3654 201587_s_at 0.5138 0.0119
GSE23400 IRAK1 3654 201587_s_at 0.6846 0.0000
GSE26886 IRAK1 3654 201587_s_at 1.0506 0.0000
GSE29001 IRAK1 3654 201587_s_at 0.5093 0.0797
GSE38129 IRAK1 3654 201587_s_at 0.8031 0.0000
GSE45670 IRAK1 3654 201587_s_at 0.5074 0.0020
GSE53622 IRAK1 3654 58226 0.6357 0.0000
GSE53624 IRAK1 3654 58226 0.6042 0.0000
GSE63941 IRAK1 3654 201587_s_at -0.3253 0.5287
GSE77861 IRAK1 3654 201587_s_at 0.6162 0.0018
GSE97050 IRAK1 3654 A_33_P3286616 0.3935 0.2283
SRP007169 IRAK1 3654 RNAseq 1.1742 0.0317
SRP008496 IRAK1 3654 RNAseq 1.6149 0.0000
SRP064894 IRAK1 3654 RNAseq 0.5470 0.0078
SRP133303 IRAK1 3654 RNAseq 1.0967 0.0001
SRP159526 IRAK1 3654 RNAseq 0.6030 0.0168
SRP193095 IRAK1 3654 RNAseq 0.6425 0.0000
SRP219564 IRAK1 3654 RNAseq 0.3903 0.1505
TCGA IRAK1 3654 RNAseq 0.2246 0.0000

Upregulated datasets: 4; Downregulated datasets: 0.  

 

Survival by IRAK1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of IRAK1:

 

No record found for this gene.

 

Somatic mutations of IRAK1:

 

Generating mutation plots.

 

Highly correlated genes for IRAK1:

 

Showing top 20/526 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
IRAK1C7orf260.758958303
IRAK1BEND30.739976606
IRAK1LIF0.734352303
IRAK1ZSWIM30.719622303
IRAK1NUBP10.715796303
IRAK1POC1A0.710698505
IRAK1PGP0.704156504
IRAK1KIF4A0.69970110010
IRAK1LRWD10.697267303
IRAK1PRR150.696322404
IRAK1BUB1B0.695555807
IRAK1TBC1D70.695112403
IRAK1LAMTOR20.687507403
IRAK1MIIP0.686397403
IRAK1PRPF190.68568807
IRAK1PUS70.683176909
IRAK1YDJC0.682955606
IRAK1LAMA50.682664403
IRAK1MRGBP0.682662807
IRAK1MPLKIP0.68197404

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